fat metabolism, unsaturated fatty acids Flashcards
hyperlipidaemia?
increased triglycerides in plasma
in which dog breed is hyperlipidaemia hereditary?
Minature schnauzers
consequence may be pancreatitis
how long does it normally take for clearance of triglycerides after a meal?
12-14 hrs
what can cats develop due to hypertryglyceraemia?
Xanthomas in the skin and other tissues
what ae the reasons for xanthomas?
hereditary
spontaneous
diabetes mellitus
high fat diet
Hypercholesterolaemia?
increased cholesterol in the plasma
features of atherosclerosis in dogs and cats?
dogs and cats are resistant to athersclerosis associated with hypercholesterolaemia
what is the reson behind the atherosclerosis resistance in dogs and cats?
because of the high circulating amount of HDL
pathogenesis of hyperlipaemia?
negative energy balance triggering excessive mobilisation of fatty acids from adipose tissue
this leads to increased hepatic triglyceride synthesis
eventually leading to fat infiltration in the liver
in which species is hyperlipaemia usually a primary disease process associated with obesity?
Horses
EMS - equine metabolic syndrome
in which species is fatty liver most commonly seen?
Dairy cattle
what are the benifits of L - carnitine in the diet believed to be?
- improving of cardiovascular health
- may help heart attack survivors
what are the disadvantages of L-carnithine in the diet?
in red meat
production of trimethylamine - N- oxide which stimulates antherosclerosis
list the features of trans fatty acids?
- Upto 15% of tissue FA
- decreased membrane fluidity
- Promotes cholesterol absorption
- may antagonise the metabolism of cis essential FAs
- Margarine
- milk (in small quantities)
- meat (in small quantities)
*
Milk and dairy products contain a considerable amount of?
Conjugated linolenic acid (CLA)
