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MISCELANEA > FARMA > Flashcards

FARMA Flashcards

1
Q

ENUMERA 7 PROFARMACOS

A
  • CODEINA
  • TRAMADOL
  • OXICODONA
  • VALACICLOVIR
  • CLOPIDOGREL
  • TAMOXIFENO
  • ISONIACIDA
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2
Q

CONCEPTO DE BIODISPONIBILIDAD

A

Fracción de dosis de un fármaco que llega inalterado a la circulacion sistémica

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3
Q

¿COMO SE AFECTA LA CONCENTRACION MAXIMA CON LA DOSIS Y CON EL VOLUMEN DE DISTRIBUCION?

A

AUMENTO DE DOSIS AUMENTA CMAX

AUMENTO DE VD DISMINUYE CMAX

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4
Q

COMO AFECTA LA LIPOSOLUBILIDAD AL VD?

A

FARMACO LIPOSOLUBLE PERMITE ALCANZAR MAYOR VOLUMEN DE DISTRIBUCION QUE UNO HIDROSOLUBLE

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5
Q

farmacos que es preciso monitorizar las concentraciones plasmaticas por tener indice terapeutico estrecho

A

litio
vanco
digoxina
aminoglucosido

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6
Q

inductores del CYP3A4

A

Fenitoina, quinidina, barbitúricos, alcohol, tabaco, rifampicina. carbamazepina. (FENix QUI va al BAR a por alcohol y tabaco se está RIFando un CARcinoma de hígado)

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7
Q

inhibidores del CYP3A4

A

Ketoconazol (Azoles), Anticoagulantes orales, Ritonavir, Cimetidina, Eritromicina (macrólidos), PomeLo (KARCEL)

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MISCELANEA (5 decks)

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