Family History and Genetics Flashcards
What is the importance of Family History
Indentify inheritance patterns
Tool to guide testing and medical diagnosis
Reproductive options
Prevention tool/change lifestyle
improve patient relationships and foster patient rapport
What can come from a family history
identify genetic risk to relatives
screening/lifestyle recommendations
educate patients
additional conditions identified
What are important components for taking family history
Be prepared
prepare the patient
control the process
open ended questions
How to do a family history
Start with proband (arrow) children and siblings one parent and their sibs and parents other parent Only do 3 generations
What ? to ask for family history
How related gender age (death) general health conditions medical documentation age of onset how diagnosed family myths background ethnicity consanguinity
What are red flags in the family history
cancer genetic syndrome multiple miscarriages common disorder with early onset early death in healthy individual genetic condition in relative
What are common conditions
cancer Heart disease DM astma mental illness HTN stroke kidney disease alcoholism learning disabilities hearing/vision loss
What is recessive
only appear in one generation
What is dominant
every generation
What is x-linked
skip every other generation
What is chromosomal
Down’s
What is Multifactoral
not every generation
