Family: Herpesviridae, Subfamily: Betaherpesvirinae

Question 1

Porcine Herpesvirus 2 common name and host

Answer 1

Inclusion body rhinitis
Porcine cytomegalovirus
In pigs 2-10 weeks old
Severe disease in piglets less than 3 weeks old

Question 2

Transmission of Inclusion Body Rhinitis

Answer 2

Primarily inhalation

Transplacental transmission

Question 3

Primary site of viral replication of Inclusion Body Rhinitis

Answer 3

Nasal mucous glands

Epithelial cells of upper respiratory tract

Question 4

Viremia pathogenesis of Inclusion Body Rhinitis

Answer 4

Neonates - bone marrow damage, anemia
Cross placenta - stillbirth, mummification, neonatal death
Localization - macrophages, endothelial and epithelial cells; endothelial cell damage and necrosis - petechial hemorrhages and edema

Question 5

Clinical signs of Inclusion Body Rhinitis in suckling pigs

Answer 5

In suckling pigs less than 3 weeks old - mucopurulent rhinitis accompanied by violent sneezing, respiratory distress, conjunctivitis, shivering, mouth breathing, death

Question 6

Clinical signs of Inclusion Body Rhinitis in neonatal piglets

Answer 6

Infected neonatal piglets appear weak, anemic or stunted, and edema around the throat and tarsal joints

Question 7

Clinical signs of Inclusion Body Rhinitis in naive, pregnant sows

Answer 7

Fetal mummification, stillbirths, neonatal deaths, and failure of piglets to thrive