Fall 2014: Week 8: Neuro: Papilledema Flashcards
1
Q
Signs to look for ONH Edema
- What are the 2 things to look for to tell if there is ONH Edema?
- Other signs?
A
- a. Is nerve elevated
b. Edema surrounding the RNFL - Indistinct borders; Hyperemia of ON; Vessel Obscuration; Dilated/Engorged Vessels; Flame HEMES; Lack of SVP; High Water Marks; Circumferential Retinal Folds around the Disc (PATON’s LINES)
2
Q
- Are Optic Disc Edema or Optic Atrophy a DIAGNOSIS?
A
- NO! They’re Findings!
3
Q
History
- Ophthalmic Symptoms?
- Neurologic
A
- Blurred vision; Transient Vision; Photopsia; Double Vision; Change in Color vision perception
- HAs; Pulsatile Tinnitus; Paresthesia or weakness; Personality Changes; Loss of Consciousness; Nausea; Nuchal Rigidity
4
Q
Papilledema
- Define
- Optic Nerve Sheaths are an Extension of what that surrounds the brain?
- CSF if found where?
- If CSF pressure increases in the brain, what does it do?
A
- Optic Nerve SWELLING due to PROVEN ELEVATED ICP!
- of the DURA
- in the Subarachnoid Spaces of the ON sheaths and of the brain
- Increases pressure in the nerve sheaths on the ONs.
5
Q
CSF
- Made in what?
- Path thru brain?
- Reabsorbed by what?
A
- Choroid Plexus
- Lateral Ventricles –> 3rd Ventricle –>(Sylvian aqueduct) 4th Ventricle –> Brain and Spinal Cord
- Cerebral Venous Drainage System
6
Q
Pressure Gradient
- Is pressure in the eye usually higher than pressure in the brain?
a. Purpose?
b. What happens when pressure in the brain goes up?
A
- YES
a. Keeps flow of Axoplasmic Material going towards the Brain (ORTHOGRADE)
b. Get a Reversal of the Pressure gradient and the AXOPLASMIC MATERIAL BACKS UP INTO THE EYE!
7
Q
Early Papilledema
- “Sick”
a. Optic Nerve Fibers?
b. ONH looks how?
c. VA?
d. VF?
e. Can it be reversed? - Chronic Papilledema (“Dead”)
a. Due to what?
b. Optic Nerve function?
c. Pallor?
d. VA?
e. VF?
f. Reversible?
A
- They still work ok.
b. Looks HYPEREMIC
c. NORMAL
d. Enlarged Blind Spots
e. Yes - a. Chronic or severely elevated ICP
b. Dead…
c. Increased
d. Reduced
e. RNFL Pattern Defects, Diffuse Constriction
f. NOPE
8
Q
Papilledema: SYMPTOMS
- HAs:
a. When are they worse?
b. They Intensify when? - Transient Visual Obscurations
a. How long do they last?
b. U/L or B/L?
c. How often do they occur? - What other two symptoms?
A
- a. Morning, and can wake Pt from thier sleep.
b. When bending over or w/Valsalva - a. a couple of seconds
b. Either
c. rarely or several times a day - Nausea and vomiting; Diplopia (Horizontal due to a CN6 palsy)
9
Q
Causes of Papilledema
- 7 of them
A
- Chiari Malformation
- Hydrocephalus
- Idiopathic Intracranial Hypertension
- Infection (Meningitis)
- Malignant Hypertension
- Space Occupying Lesion
- Venous Sinus Thrombosis
10
Q
Papilledema: Malignant Hypertension
- Systolic?
- Diastolic?
- Other signs?
A
- > 200 mmHg
- > 130 mmHg
- Hemes, CWS, Hard Exudates, Macular Edema
11
Q
Papilledema: Space Occupying Lesion
- Mass Lesions?
- Cerebral Hemorrhage
A
- ~1/4 of Pts w/Brian Tumors present w/Papilledema
2. Terson Syndrome
12
Q
Papilledema: Space Occupying Lesion: Terson Syndrome
- What is it?
- Mechanism?
A
- Subarachnoid Heme + Intraocular Heme
- Severe, Sudden rise in ICP causes an ACUTE DECREASE in Venous Drainage from the Retina, causing VENOUS STASIS and Intraocular Hemorrhaging
13
Q
Dural Venous Sinus Thrombosis
- Mechanism?
- causes (3)
- Diagnosis?
- Tx?
A
- Obstruction of 1 of the Major dural venous sinuses by a CLOT causes decreased drainage of CSF from the Subarachnoid Space
- Hypercoagulable Conditions, Infections, Neoplasm
- MRV
- Urgent Anticoagulation Therapy, Tx of the underlying Cause
14
Q
Papilledema: Meningitis
- Acute or Chronic?
- Causes? (5)
- Symptoms? (3)
- MRI?
- LP?
- Tx?
a. Infectious?
b. Carcinomatous?
A
- Either
- Bacterial, Carcinomatous, Fungal, Lyme, or Viral
- Fever, HA, Nuchal Rigidity
- Meningeal Enhancement
- CSF Analysis
- a. High-Dose IV Abs + Surgical procedures to decrease ICP
b. Radiotherapy or Chemotherapy
* Pt can present w/HA, Altered Mental Status, Phonophobia/Photophobia, Stiffness in the Neck, High Fever, Muscus membranes (Petechiae)
15
Q
Papilledema: Hydrocephalus
- What is it?
- Congenital or acquired?
A
- Obstruction to normal Flow of CSF w/in the Cranial Cavity
2. Either (Expansion of the skull occurs in infants)