Fall 2014: Lecture 8: Week 6: Disorders Of Higher Cortical Function Flashcards
- Primary Visual Cortex = ?
- Prestriate Cortex = ?
- Extrastriate Cortex = ?
- V5 is also called what?
- Striate Cortex = V1
- V2
- V3, V4, V5
- MT (Middle Temporal Area)
Aphasia
- What is it?
- Nonfluent Aphasia
a. AKA?
b. What is it? - Fluent Aphasia
a. AKA?
b. What is it?
- Hard to understand or make language
- a. BROCA’s APHASIA
b. Can’t Produce Language - a. WERNICKE’s APHASIA
b. Auditory Comprehension is bad. (Fluent, easily articulated, but PARAPHASIC SPEECH)
Alexia/Agraphia
- Alexia: Define
- Agraphia: Define
- What happens in ALEXIA without AGRAPHIA?
- Can’t Read
- Can’t Write
- Pt can still write, but CANNOT READ!
Visual Object Agnosia
- What is it?
- Involves what pathway?
- Can’t recognize previously familiar OBJECTS!
a. Can’t recognize them by sight, but might be able to describe them or recognize them via a different sense. - VENTRAL “What” Pathway
Prosopagnosia
- What is it?
a. They may have to rely on what kinds of cues?
b. Issues with it?
- Can’t recognize familiar faces or learn to recognize new faces
a. like glasses, hairstyle, gait, voice.
b. Can cause social embarrassment.
Akinetopsia
- What is it?
a. Affects what area?
- Messes with MOTION PERCEPTION (smooth moving objects look stationary or seem to “JUMP” from place to place.
a. MT/V5
Cerebral Color Vision Defects
- What is it?
- Dyschomatopsia: Define
- Achromatopsia: Define
- Hemiachromatopsia: Define
- What tests can be done?
- LOCATION?
- Don’t perceive colors properly. Damage to Visual Cortex
- Color looks dull, LESS BRIGHT
- Objects appear in shades of gray.
- Affects color discrimination in one hemifield.
- Ishihara and HRR
- Visual Cortex; U/L and C/L in Hemichromatopsia
Simultanagnosia
- Define
- Test?
- Location of injury?
- Can’t grasp the entire meaning of a picture, but can recognize individual components
- “Cookie Theft” Picture
- B/L Occipital/Parietal Lobes
Optic Ataxia
- Define
- Test?
- Location?
- Pt sees the object, but can’t reach for it accurately (Disconnect b/w Visual input and motor system)
- Ask Pt to touch various Objects
- B/L Occipital/Parietal Lobes
Ocular Motor Apraxia
- Define
- Test?
- Location?
- Can’t make voluntary saccades to look at an object of interest, despite full ocular motilities
(Use head movements to change fixation) - Ask Pt to look quickly at various objects
- B/L Occipital/Parietal Lobes
Balint Syndrome
- TRIAD (What is it?) (SOO)
- What pathway?
- Simultanagosia
Optic Ataxia
Ocular Motor Apraxia - DORSAL (“WHERE”) Pathway
Visual Neglect
- Define
- Test
- Location
- Pts WONT pay attention to STIMULI shown in the LEFT HEMIFIELD, despite full visual fields.
- Line Bisection; Clock Drawing
- Right Inferior Parietal Lobe
Blindsight
- Define
- Thought to be due to what?
- Pts w/Lesions to V1 can detect targets in the blind VF at a rate better than chance. (Spatial location, orientation, color, motion)
- Believed to be due to a RESIDUAL FUNCTION in a parallel visual processing pathway.
Anton Syndrome
- Define
- Location
- Pts that are cortically blind but are NOT AWARE of their vision loss and insist that they can see. (Pt confabulates Visual perceptions)
- B/L Occipital Lobe Lesions
- Illusion: Define
2. Hallucination: Define
- Pt has an ABNORMAL VISUAL PERCEPTION of a viewed object (Object looks WEIRD)
- Pt has a visual sensation that doesn’t correspond to a real object. (seeing something that isn’t really there)
Hallucinations
- 4 Simple (FSZC)
- Complex (4) (PACS)
- Flashes of Light
Simple Patterns/Shapes
Zig-Zag Lines
Colors - People
Animals
Complex Objects
Scenes
- Metamorphopsia
- Macropsia
- Micropsia
- Pelopsia
- Teleopsia
- Phosphenes
- Objects look Warped or distorted
- Objects are perceived as larger than reality
- Objects are perceived as smaller than reality
- Objects appear closer than reality
- Objects appear more distant than reality
- Flashes of light
Psychiatric Conditions
- Schizophrenia: What is it?
a. Visual Hallucinations in psychiatric conditions are usually associated with what?
- Most common psychiatric disorder associated w/Visual Hallucinations
a. with Auditory Hallucinations
Ophthalmic Disorders
- Metamorphopsia: Occurs when what happens?
a. Examples? - Micropsia: Occurs when what happens?
a. Example? - Macropsia: Occurs when what happens?
a. Example? - Phosphenes: Occurs when what happens?
a. Examples?
- when regular arrangement of photoreceptors is disrupted
a. ERM, Macular Edema, CNV, RPE detachment - Occurs when photoreceptors are pushed apart.
a. Macular Edema - Occurs when photoreceptors are pushed closer together
a. ERM - Vitreoretinal Traction
a. PVD, Retinal Tear
Pulfrich Phenomenon
- Define.
a. Cause?
- Altered perception of motion due to a disparity in neuronal transmission
a. Optic neuritis causing a conduction delay in one optic nerve compared to the other.
Charles Bonnet Syndrome (1)
- AKA?
- Characterized by what?
- Types of Hallucinations?
- Patients?
- Prevalence
- RELEASE HALLUCINATIONS
- by visual hallucinations associated w/Poor Vision
- Simple or Complex
Persistent or Recurrent
Usually a pleasant nature, but can be disturbing
*Static or moving
*They appear clear compared to normal blurred vision - Acquired Binocular Severe Vision Loss (AMD: MOST COMMON)…MORE COMMON in ELDERLY (Still have intellectual functions)
- Underreported due to Pts fear of being labeled as mentally ill. Misdiagnosed due to lack of familiarity of medical professionals w/the condition
Charles Bonnet Syndrome (2)
- Sensory Deprivation Theory?
a. Analogous to what Syndrome? - Prognosis?
- Tx?
- Reduced visual stimuli –> Spontaneous discharge in the Visual Cortex
a. to Phantom Limb Syndrome - Hallucinations usually disappear w/in a year to 18 months
- a. Education and reassurance
b. Interrupting vision for a short time by closing eyes or blinking can help
c. Meds: Antipsychotics, Antiepileptics, SSRIs
Dementia w/Lewy Bodies
- Visual Hallucinations are what?
- What other characteristics?
- Complex, Binocular, throughout the entire VF
2. Cognitive Impairment and Parkinsonism
Seizures
- Hallucinations are typically what?
a. They may also have what? - Mono or Bino?
- What HA type is COMMON?
- Episodes tend to occur more frequently than what?
- Simple, Brief, Flashes of colored spots or shapes
a. Motion - ALWAYS BINOCULAR
- Postictal HA is commone
- than Migraine
Peduncular Hallucinosis
- Visual Hallucinations due to what in the MIDBRAIN?
- Hallucinations are typically what?
- Damage to what?
- What is typically intact?
- INFARCT
- Complex and Mild
- to the Ascending RAS!
- Insight
Narcolepsy
- Sleep Attacks
- Cataplexy
- Sleep Paralysis
- When do they get HALLUCINATIONS?
- Episodes of unwanted sleep
- Transient Loss of Muscle tone
- Can’t move when the patient first wakes up
- When entering sleep or awakening
a. Visual, auditory, or tactile
b. Can be unpleasant and disturbing
c. Usually have the sensation of another person in the room.
Drugs: Hallucinogens
- What are the 3 main ones?
- Cocaine, LSD, PCP
* Produce a functional dissociation b/w Primary sensory cortex and Cortical Association Areas
* HPPD (Hallucinogen persisting perception disorder)
“Cocaine Bugs”
*Pulsating Geometric Shapes
Alcohol Withdrawal
- Delirium Tremens
a. Hallucinations are what 2 things?
b. What drug can help suppress the hallucinations?
c. Other symptoms?
- a. Visual and Auditory
b. Benzodiazepines
c. HAs and Seizures
Abnormal Color Perception
- Digoxin
- Sildenafil
- Yellowing of Vision (Xanthopsia) w/Toxic Levels
2. Transient Bluish Tinge (Cyanopsia) to vision