Factors Impacting Human Toxicology Flashcards

1
Q

Metabolic differences – Animal vs human

A

Benzidine acetylated in human, hydroxylated in rats

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2
Q

Factors that influence metabolism?

A
  • Sex
  • Ethnicity
  • Age
  • Body fat
  • Ethanol
  • Diet
  • Smoking
  • Co-exposures
  • Genetics
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