Biomonitoring and Human Health

Question 1

Means of evaluating exposure?

Answer 1

1. Air sampling
2. Skin sampling
3. Surface sampling
4. Biologic monitoring - measures inside body

Question 2

What is biological monitoring and what does it measure?

Answer 2

The measurement of a chemical or its metabolite in a body fluid; is a measure of absorbed dose or dose that permiated the body

Question 3

Role of biological monitoring?

Answer 3

Bridge the gap between IH measurements and a medical surveillance program

Question 4

Lauwerys’ Triangle?

Answer 4

• External exposure
• Internal Dose
• Adverse Effect

Question 5

Types of biological monitoring?

Answer 5

1. Biomarkers of Susceptibility
2. Biomarkers of Exposure
3. Biomarkers of Effect

Question 6

Biomarkers of Exposure?

Answer 6

This measurement of a substance in a body fluid is a measure of exposure and NOT a health effect (e.g. lead in blood)

Question 7

Biomarkers of Susceptibility?

Answer 7

Genetic or acquired differences in our ability to respond to exposures.

Question 8

Biomarkers of Effect?

Answer 8

Something that is measured in a body fluid that is associated with a known health impairment (e.g. protect against NOT measure)

Question 9

Where can I get specific information on what biomarkers will be useful and how to interpret the results?

Answer 9

National Center for Environmental Health (NCEH)

Question 10

Guidelines for biological monitoring?

Answer 10

BEIs (Biological Exposure Indices)

- practical guidance on sample collection, methods of analysis, and interpretation