Face Development Flashcards
What do the 5 primordia form:
- Frontonasal prominence
- 2 maxillary processes
- 2 mandibular processes
- Forehead and nose
- Upper jaw
- Lower jaw
How does the chin form
From the 2 mandibular processes coming together
Nasal pit is formed by?
Invagination of nasal placode
Maxillary processes and medial nasal swellings grow in what direction
Anteriorly
Medial nasal swellings fuse with each other and with?
Maxillary processes
What fuses to form the cheek
If they fuse too much or too little, it will affect the size of?
Maxillary and mandibular processes
The mouth
The fusion of the medial nasal processes form what 4 things?
If these fusions don’t happen properly, what will it cause
Bridge of nose, philtrum, nasal septum and primary palate
Cleft lip
Separation to nasal and oral cavities occurs with the fusion of
Primary palate (medial nasal swellings)
Primary palate and secondary palate meet up to form
Defective fusing will cause?
The incisive foramen
Cleft palate
Pierre Robin syndrome:
- __ hypoplasia
- Causing failure of ?
- How does it present
- Treatment?
- Mandibular
- Failure of tongue to descend (tongue can’t get out of the way of the developing palate)
- U shaped palate
- Tack the tongue down to the bottom of the mouth
Mandibulofacial dysostosis
- Caused by
- Other names
- Failure of neural crest cells to migrate properly
2. First arch syndrome; treacher-collins syndrome
DiGeorge syndrome:
- Deficit in neural crest supplying what 3 things?
- Causes what? (CATCH-22)
- 3rd/4th arches, pouches, and cardiac outflow tract
- Cardiac defects (tetraology), atypical facial appearance (facies), thymic hypoplasia (3rd pouch), cleft palate, hypocalcemia (3rd and 4 pouches), 22q11 deletions (chromosomal deletion on chromosome 22)
Hypocalcemia in DiGeorges syndrome is due to?
Hypoparathyroidism
