EZ 3 Flashcards
1
Q
The k1 for an enzyme inhibitor is equivalent to?
A
the Kd of the inhibitor-enzyme binding equilibrium
2
Q
When an enzyme in inhibited by a non-competitive inhibitor Kmax____ ____ and Km___
A
Vmax = decreased
Km for substrate is unchanged
3
Q
in order to be a good drug the enzyme inhibitor should ideally have____
A
a small ka value
4
Q
small ka value =
A
tight binding compound
binding as tightly as possible
tight binding - small ki = small kd
