Eyes: Visual Field Defects Flashcards

1
Q

What makes up the photoreceptors in the retina? (2)

A

Rods & cones

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2
Q

Overview of visual pathway (to the optic chiasm)

A

1) Photoreceptors (rods & cones) in the retina are stimulated by photons of light entering the eye.

2) Light-sensitive surface membrane proteins (e.g. rhodopsin) of these cells are stimulated to propagate 2nd messenger responses which convert light energy into electrical signals.

3) The photoreceptors synapse with retinal bipolar cells, which in turn transmit these signals to retinal ganglion cells.

4) The retinal ganglion cells converge at the optic disc, forming the optic nerve.

5) The optic nerve exits the eye, travelling through a defect in the lamina cribrosa of the sclera.

6) The optic nerve travels through the bony orbit and enters the middle cranial fossa through the optic canal.

7) Once inside the skull, the optic nerve travels along the floor of the middle cranial fossa, through the medial aspect of the cavernous sinus.

8) Left and right optic nerves then converge at the optic chiasm.

9) At the chiasm, fibres from the nasal aspect of each retina cross over (decussate) to the contralateral optic tract, while fibres from the temporal retina remain on their respective sides (look up image).

10) In this way, left-sided post-chiasmal fibres pertain to the right side of the visual field, and vice versa.

11) Optic tracts (L and R) then extend from chiasm to thalamus.

12) At thalamus, afferent sensory fibres from the eye synapse with 2nd order sensory neurones at the L and R lateral geniculate nucleus.

13) From here, the sensory nerves radiate dorsally to the calcarine sulcus of the occipital lobe (these are the optic radiations).

14) Optic radiations loop either through the parietal lobe or through the temporal lobe (Meyer’s loop).

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3
Q

What forms the optic nerve?

A

The retinal ganglion cells converge at the optic disc, forming the optic nerve.

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4
Q

How does the optic nerve exit the eye?

A

The optic nerve exits the eye, travelling through a defect in the lamina cribrosa of the sclera.

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5
Q

Why may the optic nerve be considered an extension of the forebrain?

A

As it is covered by the meninges of the CNS (rather than by epi/peri/endoneurium like other peripheral nerves).

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6
Q

How does the optic nerve enter the skull?

A

Enters the middle cranial fossa through the optic canal (a defect in the lesser wing of the sphenoid).

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7
Q

What bone is the optic canal in?

A

Sphenoid bone

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8
Q

Where do the L and R optic nerves converge?

A

At the optic chasm

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9
Q

Where is the optic chasm located?

A

Directly above the sella turcica of the sphenoid bone.

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10
Q

What is located immediately behind the optic chiasm?

A

The pituitary gland

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11
Q

Where does the optic tract extend from?

A

From the chiasm to the thalamus

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12
Q

What happens at the thalamus?

A

Sensory afferent nerves from the eye synapse with the 2nd order sensory neurones at the L or R lateral geniculate nucleus in the thalamus.

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13
Q

What happens in the visual pathway from the LGN?

A

L and R optic radiations.

From the thalamus, the sensory nerves radiate dorsally to the calcarine sulcus of the occipital lobe.

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14
Q

Optic radiations can reach the visual cortex in the occipital lobe by looping through one of which 2 lobes?

A

1) Parietal lobe –> upper optic radiation

2) Temporal lobe (Meyer’s loop) –> lower optic radiation

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15
Q

Optic radiations travelling through the parietal lobe correspond to which part of the visual field?

A

Upper half of the retina / lower visual field.

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16
Q

Optic radiations travelling through Meyer’s loop (in the temporal lobe) correspond to which part of the visual field?

A

Bottom half of retina / upper visual field

17
Q

Where do the optic radiations terminate?

A

In the calcarine sulcus of the occipital lobe

18
Q

Where is the cortical visual centre located?

A

In the calcarine sulcus of the occipital lobe

19
Q

What is the calcarine sulcus responsible for?

A

Retinal image processing.

Here, images from both eyes are finally collated and a final image is formed.

This image is inverted –> the brain has to re-invert the image so that information is correctly oriented in space.

From the occipital visual centre, signals are sent to the frontal, parietal and temporal lobes to further make sense of the input information (e.g. reading/facial recognition).

20
Q

What is the blood supply of the optic nerve?

A

Ophthalmic artery

21
Q

What is the blood supply of the optic chiasm?

A

Branches from the:

1) Internal carotid
2) Posterior communicating artery
3) Anterior cerebral artery
4) Anterior communicating artery

22
Q

What is the blood supply of the optic tract?

A

Middle cerebral artery

23
Q

What is the blood supply of the LGN?

A

1) Anterior choroidal branches of the MCA

2) Thalamogeniculate branches of the posterior cerebral artery (PCA)

24
Q

What is the blood supply of the optic radiations?

A

MCA

25
Q

What is the blood supply of the calcarine sulcus?

A

Mostly by the PCA. The MCA also helps supply the anterior portion, which corresponds to the macula.

26
Q

As a rule, what type of visual field defect will pre-chiasmal lesions result in?

A

Ipsilateral monocular visual field defects (i.e. one eye affected).

27
Q

As a rule, what type of visual field defect will post-chiasmal lesions result in?

A

Homonymous visual field defects of the contralateral side.

28
Q

What visual field defect will lesions of the optic chiasm most commonly result in?

A

Bitemporal hemianopia

29
Q

What visual field defect do lesions to the optic tract result in?

A

Homonymous contralateral hemianopia

30
Q

What visual field defect do lesions to the optic radiations result in?

A

Homonymous contralateral quadrantanopia.

Those affecting Meyer’s loop –> homonymous upper quadrantanopia (“pie in the sky”).

Those affecting parietal lobe –> homonymous a lower quadrantanopia (“pie on the floor”).

Mnemonic = PITS (Parietal-Inferior, Temporal-Superior)

31
Q

What visual field defect do lesions affecting the calcarine sulcus of the occipital lobe tend to cause?

A

Homonymous hemianopia with sparing of the macula.

32
Q

Why is there macular sparing in lesions affecting the calcarine sulcus of the occipital lobe tend?

A

Given the dual blood supply to the anterior portion of the visual centre (PCA and MCA).

33
Q

For a lesion located at the optic nerve, give the:

a) field defect

b) typical lesions

A

a) ipsilateral monocular blindness

b)
- optic neuritis
- amaurosis fugax
- optic atrophy
- retrobulbar optic neuropathy
- trauma

34
Q

For a lesion located at the optic chiasm (central), give the:

a) field defect

b) typical lesions

A

a) bitemporal hemianopia

b)
- pituitary adenoma e.g. prolactinoma
- suprasellar aneurysm

35
Q

For a lesion located at the optic chiasm (lateral), give the:

a) field defect

b) typical lesions

A

a) ipsilateral monocular nasal hemianopia

b)
- distension of the 3rd ventricle
- internal carotid/posterior communicating artery atheroma

36
Q

For a lesion located at the optic tract, give the:

a) field defect

b) typical lesions

A

a) contralateral homonymous hemianopia

b)
- MCA stroke
- tumours

37
Q

For a lesion located at the optic radiation, give the:

a) field defect

b) typical lesions

A

a) contralateral homonymous quadrantanopia

b)
- MCA stroke
- tumour
- trauma

38
Q

For a lesion located at the occipital cortex, give the:

a) field defect

b) typical lesions

A

a) Contralateral homonymous hemianopia with macular sparing

b)
- PCA stroke
- trauma

39
Q
A