Eyelids/Orbit/Optic Nerve

Question 1

An incision through the gray line of the eyelid margin between what and what?

Answer 1

Orbicularis and the tarsus

Question 2

What is acanthosis?

Answer 2

Increased thickness of stratum malpighii of the epidermis

Question 3

What is hyperkeratosis?

Answer 3

Increased thickness of the stratum corneum of the epidermis

Question 4

What is parakeratosis?

Answer 4

Retention of nuclei within the stratum corneum

Question 5

What is dyskeratosis?

Answer 5

Premature individual cell keratinization

Question 6

What is acantholysis?

Answer 6

Loss of cohesion between adjacent epithelial cells.

Question 7

What is the inheritance and sssociations of distichiasis?

Answer 7

AD

1. Mandibulofacial dystosis
2. Tisomy 18

Question 8

What is a Zimmerman tumor?

Answer 8

Aberrant location of lens epithelium within the inferonasal porition of the lower eyelid

Question 9

Muir-Torre syndrome is s/w what on the eyelid?

Answer 9

Its a visceral carcinoma - usually of the colon; Keratoacanthoma, sebaceous neoplasm;

Question 10

What is the cutaneous horn form of seborahhic keratosis?

Answer 10

Inverted follicular keratosis

Question 11

What is a Spitz nevus?

Answer 11

Develop late in childhood and are uncommon after the second decade. They are larger - up to 1.0 cm - and have a pink-red color.

Question 12

What are the 2 primary neoplasms of the orbit?

Answer 12

1. Hemangioma

2. Lymphoma

Question 13

How does a pleomorphic adenoma look histologically?

Answer 13

A mixture of epithelial and stromal elements and may contain heterologous elements such as cartilage and bone

Question 14

Lymphangiomas are encapsulated?

Answer 14

FALSE

Question 15

Hemangiopericytoma histologically looks?

Answer 15

Staghorn vascular pattern;

reticulin stain - useful in demonstrating tumor cells that are individually wrapped in a network of collagenous material

Question 16

In rhabdomyosacroma embroynal type what do you see histololgically?

Answer 16

Cross striations

Question 17

What are the two types of cells seen in a schwannoma?

Answer 17

1. Antoni A - spindle cells arranged in interlacing cords that may form Verocay bodies
2. Antoni B - made up of stellate cells with mucoid stroma

Question 18

Rosenthal fibers are found in what?

Answer 18

ON gliomas - deeply eosinophilic filaments

Question 19

Where do Optic nerve menigomas arise?

Answer 19

Arachnoid. They may invade the nerve and extend through the dura mater to invade muscle.

Question 20

Psammoma bodies are found in what?

Answer 20

Optic nerve menigiomas with WHORLS.

Question 21

Parakeratosis is characteristic of what lesion and define it?

Answer 21

Actinic keratosis; retention of nuclei in the keratin layer and epidermis lacks the granular layer

Question 22

What has a fibrovascular core with chronic inflm with epidermal frond and hyperkeratosis?

Answer 22

Squamous papilloma

Question 23

What does a seborrehic keratosis look like?

Answer 23

hyperkeratosis with pseudo-horn cyst

Question 24

What does syringoma look like?

Answer 24

Tad pole ductles

Question 25

Which dz is granulomatous PAN or Wegener’s?

Answer 25

Wegener’s ; PAN is nongranulomatous

Question 26

Most orbital lymphomas are what?

Answer 26

Monoclonal B cell tumors

Question 27

What does a MALToma look like?

Answer 27

Well differentiated lymphocytes with diffuse monomorphous sheet of cells with NO GERMINAL CENTERS
(a/w H pylori infection)

Question 28

What do you see in optic atrophy?

Answer 28

Redundant dura, widening of the pia and pial septa

Question 29

Fibrous ingrowth is essentially what?

Answer 29

Stromal overgrowth

Question 30

Bowen’s dz is a/w what?

Answer 30

SqCC

Question 31

Small blue cell tumor with cross striations, strap cells and loose myxomatous matrix is?

Answer 31

Rhabdomyosarcoma

Question 32

Which d/o has INDIVIDUAL cells surrounded by reticulin?

Answer 32

Hemangiopericytoma

Question 33

What is unique about sarcoid of the optic nerve vs the eye itself?

Answer 33

The nerve can have GRANULOMATOUS and nongranulomatous infm