Eyelids/Orbit/Optic Nerve Flashcards

1
Q

An incision through the gray line of the eyelid margin between what and what?

A

Orbicularis and the tarsus

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2
Q

What is acanthosis?

A

Increased thickness of stratum malpighii of the epidermis

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3
Q

What is hyperkeratosis?

A

Increased thickness of the stratum corneum of the epidermis

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4
Q

What is parakeratosis?

A

Retention of nuclei within the stratum corneum

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5
Q

What is dyskeratosis?

A

Premature individual cell keratinization

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6
Q

What is acantholysis?

A

Loss of cohesion between adjacent epithelial cells.

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7
Q

What is the inheritance and sssociations of distichiasis?

A

AD

  1. Mandibulofacial dystosis
  2. Tisomy 18
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8
Q

What is a Zimmerman tumor?

A

Aberrant location of lens epithelium within the inferonasal porition of the lower eyelid

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9
Q

Muir-Torre syndrome is s/w what on the eyelid?

A

Its a visceral carcinoma - usually of the colon; Keratoacanthoma, sebaceous neoplasm;

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10
Q

What is the cutaneous horn form of seborahhic keratosis?

A

Inverted follicular keratosis

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11
Q

What is a Spitz nevus?

A

Develop late in childhood and are uncommon after the second decade. They are larger - up to 1.0 cm - and have a pink-red color.

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12
Q

What are the 2 primary neoplasms of the orbit?

A
  1. Hemangioma

2. Lymphoma

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13
Q

How does a pleomorphic adenoma look histologically?

A

A mixture of epithelial and stromal elements and may contain heterologous elements such as cartilage and bone

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14
Q

Lymphangiomas are encapsulated?

A

FALSE

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15
Q

Hemangiopericytoma histologically looks?

A

Staghorn vascular pattern;

reticulin stain - useful in demonstrating tumor cells that are individually wrapped in a network of collagenous material

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16
Q

In rhabdomyosacroma embroynal type what do you see histololgically?

A

Cross striations

17
Q

What are the two types of cells seen in a schwannoma?

A
  1. Antoni A - spindle cells arranged in interlacing cords that may form Verocay bodies
  2. Antoni B - made up of stellate cells with mucoid stroma
18
Q

Rosenthal fibers are found in what?

A

ON gliomas - deeply eosinophilic filaments

19
Q

Where do Optic nerve menigomas arise?

A

Arachnoid. They may invade the nerve and extend through the dura mater to invade muscle.

20
Q

Psammoma bodies are found in what?

A

Optic nerve menigiomas with WHORLS.

21
Q

Parakeratosis is characteristic of what lesion and define it?

A

Actinic keratosis; retention of nuclei in the keratin layer and epidermis lacks the granular layer

22
Q

What has a fibrovascular core with chronic inflm with epidermal frond and hyperkeratosis?

A

Squamous papilloma

23
Q

What does a seborrehic keratosis look like?

A

hyperkeratosis with pseudo-horn cyst

24
Q

What does syringoma look like?

A

Tad pole ductles

25
Which dz is granulomatous PAN or Wegener's?
Wegener's ; PAN is nongranulomatous
26
Most orbital lymphomas are what?
Monoclonal B cell tumors
27
What does a MALToma look like?
Well differentiated lymphocytes with diffuse monomorphous sheet of cells with NO GERMINAL CENTERS (a/w H pylori infection)
28
What do you see in optic atrophy?
Redundant dura, widening of the pia and pial septa
29
Fibrous ingrowth is essentially what?
Stromal overgrowth
30
Bowen's dz is a/w what?
SqCC
31
Small blue cell tumor with cross striations, strap cells and loose myxomatous matrix is?
Rhabdomyosarcoma
32
Which d/o has INDIVIDUAL cells surrounded by reticulin?
Hemangiopericytoma
33
What is unique about sarcoid of the optic nerve vs the eye itself?
The nerve can have GRANULOMATOUS and nongranulomatous infm