Eye and Ear therapeudics Flashcards

1
Q

IOP

A

~15mm Hg is normal

above 21 at increased risk of glaucoma

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2
Q

Open angle glaucoma

A

most common form
slow clogging of drainage canals
wide open angle between iris and cornea
symptoms go unnoticed

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3
Q

Angle closure glaucoma

A

sudden rise in IOP

Closed or narrow angle between iris and cornea DEVELOPS VERY QUICKLY

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4
Q

Irido-corneal angle

A

usually 45 degrees

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5
Q

Timolol

A

beta blocker- decreases aqueous humor secretion (open angle)

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6
Q

Lantaoprost

A

prostaglandin
increases outflow of aqueous humor
(open angle)

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7
Q

Gonioscopy

A

examination quantifies the anterior chamber angle using a goniolens

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8
Q

Tonometry

A

measures IOP

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9
Q

Opthalmoscopy

A

examination of optic nerve shape and color to detect glaucoma damage

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10
Q

T/F high IOP usually indicates galucoma

A

F, ocular hypertension.its only a risk factor

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11
Q

Pilocarpine

A

Choliomimetic
Contracts ciliary muscle and increases outflow of humor.
Used for OAG

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12
Q

ACG treatments

A

PRESURGICAL

Pilocarpine, phygostigmine, acetazolamide, glycerol, mannitol

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13
Q

AMD

A

age related macular degenerationsmoking is risk factor

not painful

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14
Q

Wet AMD

A

neovascular. proliferation of vessels in subretinal space.

Progress to disease faster than dry

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15
Q

Dry AMD

A

build up of cellular debris between retina and choroid

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16
Q

Antioxidants

A

believed to help, but not proven.

17
Q

Verteporfin

A

injected intravenously in eye then its light activated to destroy new vessel.

18
Q

Pegaptanib

A

oligopeptide injected into vitreous humor. works as antagonist to VEGF, which reduces growth of vessels

19
Q

Bevacizumab

A

Monoconal AB for AMD cheaper

20
Q

Ranibizumab

A

Monoclonal AB for AMD VERY EXPENSIVE

21
Q

Meniere’s Disease

A
endolymphatic hydrops
Several factors may contribute to changes in this fluid level and trigger Meniere’s Disease:
•  Improper fluid drainage
•  Abnormal immune response
•  Allergies
•  Viral infection
•  Genetic predisposition
•  Head trauma
•  Migraines
22
Q

Meclizine

A

antivert antagonist at H1, antihistamine, anticholinergic, CNS depressant

23
Q

Diazepam

A

used because of sedative and anxiolytic effects. reduces motion sickness

24
Q

Promethazine

A

H1 blocker, anticholinergic, antinausea and motion sickness, XEROSTOMIA.

25
Q

triampterene + hydrochlorothiazide

A

diuretic- to help regulate fluid volume and pressure in inner ear

26
Q

dexamethazone

A

Long acting steroid
inject into ear.
helps control vertigo attacks.

27
Q

Amoxi + clavulanic acid

A

2nd line for recurrent OM azithromycin or clinda if allergic

28
Q

Retinoblastoma

A

Most common tumor in children