Exxcellence pearls: risks of hormone therapy

Question 1

What are the increased risks of combined hormone therapy?

Answer 1

Increased risk of thromboembolism, gallbladder disease, breast cancer heart disease and stroke, Alzheimer’s disease and dementia. Estrogen therapy alone is associated with a small increased risk of ovarian cancer and unopposed estrogen in women with intact uteri are associated with increased risk of endometrial hyperplasia and cancer