Extracranial Cerebrovascular Flashcards
What does spectrum analysis sort out?
the doppler frequencies FFT - giving us a velocity
What is extracranial?
outside the brain
carotid studies
What are we evaluating in spectrum analysis blood flow?
pulsatile
flow is slower at the periphery
vessels are not straight
vessels are not uniform
distorted by pathology
What is the proper doppler angle?
60 degrees or less to acquire accurate frequency and velocity information
What is a doppler spectrum
graph of doppler frequencies generated by moving blood
When do you have broad systolic peak and forward flow throughout diastole?
CCA, ICA, vertebral, renal and celiac
low peripheral resistance
entire waveform above or below baseline
When do you get tall, narrow sharp systolic peaks reversed or absent flow through diastole?
extremity artieries, ECA, SMA (fasting)
high peripheral resistance
Arterial flow
What varies depending on location, physiology and pathology alteration, status of cardiac function?
Pulsatility
When does flow velocity accelerate rapidly?
in systole
What might cause acceleration to be slowed?
severe arterial obstruction flow
What causes disturbed flow?
widening of the wave form
vascular disease
normal tortuous vessels
prominent area -bulb
What happens with arterial obstruction?
increase velocity
disturbed flow post stenotic
proximal pulsatility changes
distal pulsatility changes
indirect effects - collateralization
What is Poiseuille’s Law?
a statement of physics
the VELOCITY of the steady flow of a fluid through a narrow TUBE varies DIRECTLY as the PRESSURE and the 4th power of the RADIUS of the tube and INVERSELY as the LENGTH of the tube and the coefficient of VISCOSITY.
what law states: because volume flow is porportional to the 4th power of the radius, even small changes in radius can result in large changes in flow?
Poiseuille’s Law
calculates VOLUME FLOW
Radius is most important because its to the 4th power
According to Poiseuille’s Law what happens to flow rate when pressure, diameter, length and viscoisty is INCREASED?
increase pressure, increase flow rate
increase diameter, increase flow rate
increase length, decrease flow rate
increase viscosity, decrease flow rate
How does Bernoulli’s principle relate velocity and pressure?
they are inversely related
high velocity, low pressure
low velocity, high pressure
With Bernoulli’s principle if you have a stenosis, what happens to the pressure and velocity AT the stenotic segment, prox to stenosis and distal to stenosis?
Stenotic segment - pressure decreases, velocity increases
prox - pressure increase
distal - pressure increase
Flow moves along the path of _________resistance
least
What is a hallmark of high resistance vascular beds?
diastolic flow reversal
it doesn’t need a constant flow, it can hesitate….flow reversal
What is an ischemic stroke?
interruptions of blood flow to the brain
80% - ruptured intracraninal blood vessel
20% intracranial hemorrhage
What are two ways the blood flow gets interrupted to the brain causing a stroke?
Thrombus lodges in a cerebral artery
thrombus in the carotid artery breaks off and travels to a cerebral artery in the brain
What is responsible for more than 50% of all strokes?
extracranial carotid artery disease
What is the third leading cause of death in the USA?
Stroke (cerebrovascular diseases) 137,119
What can detect potential causes of stroke?
carotid imaging
What is the definition of stroke or CVA?
permanent ischemic deficit (permanent damage)
What is the definition of TIA (transient ischemic accident)
temporary - reversible ischemic neurologic deficit
resolves in <24 hr (usually less than one hour)(lasts 1-30 min until full recovery)
What is the definition of RIND?
reversible ischemic neurologic deficit
resolves in >24 hrs (up to three weeks for complete restoration of function)
What is the leading cause of permanent disability?
strokes
What is the best treatment for stroke?
prevention
What is a thrombotic stroke?
clot in the artery in the brain
what is an embolic stroke?
piece of a clot is carried to the brain ( or anywhere)
What is a hemorrhagic stroke?
blood vessel in the brain breaks
What are the non-modifiable risk factors for stroke?
age - risk increases with age
sex - males
race - higher in african american
previous stroke
What are the modifiable or controllable risk factors for stroke?
hypertension
atrial fibrillation
cardiac disease
diabetes mellitus
elevated cholestrol
smoking
sedentary lifestyle
obesity