Extracellular Matrix Flashcards

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1
Q

ECM

A

Extracellular Matrix

Forms connective tissues, tendons, ligaments

Important roles in cell migration, division and differentiation

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2
Q

Three components of ECM

A

Structural (collagen and elastin)

Filler (proteoglycans)

Adhesive glycoproteins (fibronectin, laminins)

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3
Q

Collagen

A

Self assemble into trimers

Can form homo or hetereo trimers

Polypeptide chain > trimeric protein > collagen fibril > collagen fiber

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4
Q

Elastin

A

Hydrophobic protein

Mostly glycine, alanine, valine, proline

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