Extracellular Matrix Flashcards
1
Q
ECM
A
Extracellular Matrix
Forms connective tissues, tendons, ligaments
Important roles in cell migration, division and differentiation
2
Q
Three components of ECM
A
Structural (collagen and elastin)
Filler (proteoglycans)
Adhesive glycoproteins (fibronectin, laminins)
3
Q
Collagen
A
Self assemble into trimers
Can form homo or hetereo trimers
Polypeptide chain > trimeric protein > collagen fibril > collagen fiber
4
Q
Elastin
A
Hydrophobic protein
Mostly glycine, alanine, valine, proline