extra stuff Flashcards

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1
Q

which specific hallucinations suggest a diagnosis of schizofrenia?

A
  • 3rd party auditory schizofrenia

- Voices echoing patients thought

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2
Q

positive symptoms?

A

delusions

hallucinations

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3
Q

Schneiderโ€™s first rank symptoms include?

ABCD

A

A - Auditory Hallucinations.
B - Broadcasting of Thought.
C - Controlled Thought (delusions of control).
D - Delusional Perception.

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4
Q

other symptoms in schizophrenic psychosis?

A

Perplexity
thought insertion
Incongruous affect

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5
Q

clinical features of schizofrenia?

A

Psychosis:
halluciantaion
dellusions
thought disorder

cognitive symptoms:
Impaired attention, memory and executive functions

Negative Symptoms:
Asociality
Alogia-poverty of speech
Anhedonia

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6
Q

brain changes in schizofrenia?

A

Enlarged ventricles

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7
Q

what Ido people think the cause of schizofrenia is?

A

Hyperdopminergic Theory
NMDA receptor hypofunction
Impairment of GABA signaling
Serotonin Theory

dopinergic pathway

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8
Q

what pathway is responsible for DA overactivity associated with positive symptoms.

A

Meso-limbic Dopamine Pathway

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9
Q

DA underactivity associated with negative symptoms

A

Meso-cortical Dopamine Pathwa

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10
Q

D2 blockade by antipsychotic Px associated with Parkinsonian side-effects.

A

Nigrostriatal Dopamine Pathway

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11
Q

D2 blockade by antipsychotic Px leads to increased Prolactin levels and Hyperprolactinaemia.
Which pathway is responsible for this?

A

Tuberoinfundibular Dopamine Pathway

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12
Q

only one drug has been shown to cause no Tardive Dyskinesia.

What is it?

A

Clozapine

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13
Q

atypical antipsychotics?

A

Olanzapine
Risperidone
Clozapine

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14
Q

typical antipsychotics?

A

Chloropromazine

Haloperidol

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15
Q

Given his past psychiatry history his parents can sign him into a psychiatric hospital against his will.
T/F

A

F

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16
Q

how long can an emergency detention run?

A

72hours

17
Q

who can undertake A Short Term (28 day) Detention

A

Approved Medical Practitioner (AMP) only

18
Q

what can increase the rate of relapse in schizophrenia?

A

Non compliance to treatment
Misuse of illicit substances
C. High Expressed Emotion at home
Major Life Events

19
Q

Side affects of Clozapine

A
Neutropenia	   	   	
Seizures	   	   
Idiopathic hyperthermia	   	   	
Weight gain	   	   	
Hypersalivation
20
Q

Psychiatric drugs can directly cause physical disease.

3 main conditions to be aware of

A

Weight Gain and Obesity.
Diabetes.
Metabolic Syndrome: Obesity, Hypertension, Dyslipidaemia and Abnormal Glucose Metabolism

21
Q

what drugs can cause hyperprolactinaemia?

A

Amisulpride,
Risperidone,
Typical Antipsychotics.

22
Q

hyperprolactinaemia causesโ€ฆ

A
Galactorrhea.
Menstrual irregularities.
Sexual dysfunction.
Osteoporosis.
Increased risk breast cancer.
Serum Prolactin levels should be checked if any pt reports such symptoms.
23
Q

All patients should have โ€ฆ prior to starting antipsychotics.

A

ECG

and record BMI

24
Q

proven to be effective psycho-social interventions in the management of schizophrenia?

A
Family Therapy	   	   	
B. CBT	   	   	
C. Social Skills Training	   	   	
D. Compliance Therapy	   	   	
E. Supported Employment

NOT Individual Psychodynamic Psychotherapy- DOESNT HELP

25
Q

Factors associated with a good outcome in Schizophrenia include

A

Being married

Prominent affective symptoms