extra stuff Flashcards
which specific hallucinations suggest a diagnosis of schizofrenia?
- 3rd party auditory schizofrenia
- Voices echoing patients thought
positive symptoms?
delusions
hallucinations
Schneider’s first rank symptoms include?
ABCD
A - Auditory Hallucinations.
B - Broadcasting of Thought.
C - Controlled Thought (delusions of control).
D - Delusional Perception.
other symptoms in schizophrenic psychosis?
Perplexity
thought insertion
Incongruous affect
clinical features of schizofrenia?
Psychosis:
halluciantaion
dellusions
thought disorder
cognitive symptoms:
Impaired attention, memory and executive functions
Negative Symptoms:
Asociality
Alogia-poverty of speech
Anhedonia
brain changes in schizofrenia?
Enlarged ventricles
what Ido people think the cause of schizofrenia is?
Hyperdopminergic Theory
NMDA receptor hypofunction
Impairment of GABA signaling
Serotonin Theory
dopinergic pathway
what pathway is responsible for DA overactivity associated with positive symptoms.
Meso-limbic Dopamine Pathway
DA underactivity associated with negative symptoms
Meso-cortical Dopamine Pathwa
D2 blockade by antipsychotic Px associated with Parkinsonian side-effects.
Nigrostriatal Dopamine Pathway
D2 blockade by antipsychotic Px leads to increased Prolactin levels and Hyperprolactinaemia.
Which pathway is responsible for this?
Tuberoinfundibular Dopamine Pathway
only one drug has been shown to cause no Tardive Dyskinesia.
What is it?
Clozapine
atypical antipsychotics?
Olanzapine
Risperidone
Clozapine
typical antipsychotics?
Chloropromazine
Haloperidol
Given his past psychiatry history his parents can sign him into a psychiatric hospital against his will.
T/F
F
how long can an emergency detention run?
72hours
who can undertake A Short Term (28 day) Detention
Approved Medical Practitioner (AMP) only
what can increase the rate of relapse in schizophrenia?
Non compliance to treatment
Misuse of illicit substances
C. High Expressed Emotion at home
Major Life Events
Side affects of Clozapine
Neutropenia Seizures Idiopathic hyperthermia Weight gain Hypersalivation
Psychiatric drugs can directly cause physical disease.
3 main conditions to be aware of
Weight Gain and Obesity.
Diabetes.
Metabolic Syndrome: Obesity, Hypertension, Dyslipidaemia and Abnormal Glucose Metabolism
what drugs can cause hyperprolactinaemia?
Amisulpride,
Risperidone,
Typical Antipsychotics.
hyperprolactinaemia causes…
Galactorrhea. Menstrual irregularities. Sexual dysfunction. Osteoporosis. Increased risk breast cancer. Serum Prolactin levels should be checked if any pt reports such symptoms.
All patients should have … prior to starting antipsychotics.
ECG
and record BMI
proven to be effective psycho-social interventions in the management of schizophrenia?
Family Therapy B. CBT C. Social Skills Training D. Compliance Therapy E. Supported Employment
NOT Individual Psychodynamic Psychotherapy- DOESNT HELP
Factors associated with a good outcome in Schizophrenia include
Being married
Prominent affective symptoms
