alcohol-liver

Question 1

safe limit of alcohol?

Answer 1

ZERO!

no safe amount of alcohol

Question 2

what happens to liver with alcohol abuse?

Answer 2

fatty liver

then

cirrhosis of liver

Question 3

acute alcohol hepatitis diagnosis?

Answer 3

Alcohol intake > 6u / day

Jaundice with Bilirubin > 80mg/dl

No other aetiology for Liver inflammation

Very high Mortality / No specific treatment yet

Question 4

what score is given to alcohol hepatitis patients?

Answer 4

GAHS

Question 5

if GAHS ≥ 9?

Answer 5

30 day mortality
Without steroids 48%
With steroids 22%

84 day mortality
Without steroids 62%
With steroids 41%

Question 6

how does alcohol affect nutrition?

Answer 6

60 % of chronic abusers have malnutrition

Most of the calories is from Alcohol

Total energy intake is reduced
Nausea & Vomiting
Abdo pain
Diarrhoea

Question 7

Mortality in Alcoholic Cirrhosis

Answer 7

75% die of Liver decompensation

20-25% Hepatocellular cancer sequelae

Question 8

what is the most common indication of liver transplant?

Answer 8

ARLD is the most common indication
Resistant complications of Cirrhosis
Jaundice
Ascites
Encephalopathy
Coagulopathy

Hepatocellular Cancer

Question 9

what LFT do you see in teenagers?

Answer 9

Deranged LFTs are common especially in Obese teenagers

Exposure to Alcohol <14 yrs
Strongly associated with later alcohol abuse & dependence
RR 2.3-4.0