Extra Information for Unit 3 Exam Flashcards
Cells in Gastric Gland
- Mucous neck cells
- Parietal cells
- Chief cells
- Enteroendocrine cells
Mucous neck cells-secret mucus
Parietal cells-secrete hydrochloric acid and intrinsic factor. Instrinsic factor captures vitamin B12 that allows RBC production.
Chief cells-secrete pepsinogen
Enteroendocrine cells-secrete gastrin
Goblet cells
secrete mucus
Paneth cells
inhibit microbial invasion
Stem cells
dividing to create new population of simple columnar epithelium.
How is the small intestine specialized for absorption?
It contains microvilli that increase surface area. It also contains alots of blood capillaries for transportation of food molecules all over the body.
Mucosal Barrier (protection of stomach against low pH)
- layer of bicarbonate rich mucus produced by mucus cap cells to neutralize acid in stomach.
- tight junctions between epithelial cells
- damaged epithelial cells are quickly replaced by stem cells
Duodenum protections from acidic chyme
-duodenal glands secreting alkaline mucus neutralize acidic chyme
How T3 and T4 are made?
Follicular cells secrete thyroglobulin into the lumen. Iodide from the capillary goes through the follicular cells and become iodine when it reaches lumen. Thyroglobulin and iodine combines and becomes the colloid. Colloid is endocytosed into follicular cell and combine with a lysosome. Lysosome enzyme cleave colloid which become T3 and T4. T3 is ten time more active than T4.