Ext. Mendelian Inheritance Lecture 15 Flashcards
a phenotype intermediate between the homozygous dominant and homozygous recessive phenotypes
incomplete dominance
in human blood groups the fact that an individual can have an AB blood type is an example pf
codominance
An individual with type a blood and an individual with type B blood mate and have an offspring. What is the only blood type can you be CERTAIN is possible in their offspring?
type AB blood
Epistasis is
when one gene can mask the expression of a second gene
sickle-cell anemia in humans is an example of
overdominance/heterozygote advantage
term that refers to the situation where the effects of one gene mask the phenotype effects of another gene
epistasis
the multiple effects of a single gene on the phenotype of an organism is called
pleiotropy
one with potential to cause death inherited in recessive manner and usually resulted from mutations
lethal allele
allele dominant in one sex nd recessive in another
sex-influenced inheritance
an allele doesn’t always “penetrate” into the phenotype of the individual
incomplete penetrance
heterozygote is more vigorous than two homozygous
overdominance / heterozygote advantage
three or more alleles eg ABO blood type
multiple allele system
each recessive allele is complemented by wild type allele - indicates recessive alleles are in different genes
complementation
overdominance reasons
- disease resistance
- homodiner formation
3, variation in functional activity
multiple effects of a single gene on the phenotype
pleiotropy