Exp 6.2: Lipids (Classifications) Flashcards
Type of Lipid:
Group of signal lipids
Eicosanoids
Type of Lipid:
Derived from metabolism of arachidonic acid by enzyme cyclooxygenase (COX)
Eicosanoids
3 subtypes of eicosanoids
Prostaglandins
Thromboxanes
Leukotrienes
Type of Lipid:
Derived mainly from arachidonic acid
Eicosanoids
Subtype of Eicosanoids:
Have a variety of potent biological activities of hormonal or regulatory nature
Prostaglandins
Subtype of Eicosanoids:
parent compound of prostaglandins
Prostanoic acid
Subtype of Eicosanoids:
Control blood pressure
Prostaglandins
Subtype of Eicosanoids:
Stimulate muscle contraction
Prostaglandins
Subtype of Eicosanoids:
Inhibit platelet aggregation
Prostaglandins
Subtype of Eicosanoids:
Induce inflammation
Prostaglandins
Subtype of Eicosanoids:
Platelet aggregation and vasoconstriction
Thromboxane A2
Subtype of Eicosanoids:
Inhibit the synthesis of thromboxane by inhibiting the COX enzyme
Aspirin and other NSAIDs (Thromboxanes)
Subtype of Eicosanoids:
Synthesized from arachidonic acid
Leukotrienes
Subtype of Eicosanoids:
Occur mainly in leukocytes
Leukotrienes
Subtype of Eicosanoids:
Produce muscle contractions
o Lungs
o Cause asthma-like attacks
Leukotrienes
Subtype of Eicosanoids:
Recently developed anti-asthma drugs
o Inhibit the synthesis of ____________
Leukotrienes
Type of Lipid:
Comprise the bulk of storage fat
glycerolipids
Type of Lipid:
Mono-, di- and tri- substituted glycerols
glycerolipids
1 Subtype of glycerolipids
Triacylglycerols
Subtype of Glycerolipids:
Lipids formed by esterification of three fatty acids to glycerol
Triacylglycerols
Subtype of Glycerolipids:
Neutral lipid
Triacylglycerols
2 subtypes of glycerophospholipids
Phosphoacylglycerol
Phosphatidylcholine (lecithin)