Exocrine Pancreas Flashcards
How can the pancreas obstruct the duodenum?
annular ring
embryological malformation
causes duodenal obstruction
Acute pancreatitis from activation of
trypsin first
Most common causes of acute pancreatitis
gallstones
alcohol
Serum markers for acute pancreatitis
lipase and amylase
lipase more specific for pancreatitis
Hypocalcemia in acute pancreatitis
Ca2+ bound up in soaponification of fat in fat necrosis of peripancreatic fat
Acute pancreatitis in children
MVA trauma (seatbelt over abdomen) *CF causes chronic pancreatitis
Chronic pancreatitis etiologies
CF in children
EtOH in adults
*both are chronic conditions
Complications of chronic pancreatitis
malabsorption (steatorrhea, KADE deficiency)
dystrophic calcifications
risk of adenocarcinoma of pancreas
2˚ DM
Migratory thrombophlebitis
swelling, erythema, and extremities tenderness
in pancreatic adenocarcinoma
Sx of pancreatic adenocarcinoma
@ head: obstructive jaundice w/ pale stools and palpable gallbladder