Exercise and CVS Flashcards
Benefits of exercise
CNS - Reduces risk of stroke, dementia, depression
CVS - Reduces risk of CAD, obesity, BP, DM, LDL; 13% decrease in cardiac mortality per MET
Onco - Reduces risk of breast, prostate and bowel CA
MSK - Reduces risk of falls, osteoporosis, disability
MET definition
Metabolic unit used to quantify PA intensity; ratio of metabolic rate during exercises to metabolic rate at rest
0 MET = No regular exercise
4 MET = Walking 4mph
10 MET = Brisk jogging
Risks of exercises
Increased risk of sudden cardiac death
Triggers of SCD in athletes
Acid base and electrolyte imbalance
dehydration
adrenergic surges
Aetiology of SCD
- Channelopathies
Long QT syndrome
Brugada syndrome
Cathecholaminergic polymorphic VT - Cardiomyopathies
HOCM
Arrhythmogenic RV Cardiomyopathy
Dilated cardiomyopathy - Coronary Artery disease
Atherosclerosis
Anomalous coronary ostia
Causes for those with normal heart
- channelopathies
- WPW syndrome
- comotio cordis
- drugs
- electrolyte disturbances
What is the peak age (per 100,000)
Around 40-50
Mean age
23yo (40% of deaths at <18yo)
Epidemiology of SCD
1/ 4,000 to 1/50,000 per year M>F (9:1) black > white football and basketball 90% during or immediately after exertion 80% asymptomatic prior
Clinical Presentation
FHx
- known heritable disorder
- premature death (<50)
- SCD
- epilepsy
- unexplained drowning
- road traffic accident
Sx
- EXERTIONAL = chest pain, dyspnoea, dizziness, excessive breathlessness, palpitation, epilepsy, prior cardiac disease
O/E
Check weight, peripheral signs around eyes and roof of mouth, pulse and BP, CVS examination
Ix
- ECG diagnostic in accessory pathways, channelopathies, conduction tissue disorders; 95% HCM abnormal and 80% ARVC
- ECHO
- Stress ECG
- MRI
Hypertrophic Cardiomyopathy
Commonest cause of SCD in young athletes
LV outflow tract obstruction from asymmetric septal hypertrophy
Sx
- Chest pain, dyspnoea, palpitations, presyncope, syncope
- Aborted SCD
- Asymptomatic
FHx of HCM or SCD in 1st degree relative
Ix ECG positive in 95% - LVH voltage criteria - T wave inversion inferior lateral - ST depression - Q waves - LBBB ECHO
Individualised therapy
- lifestyle modifications
- medical therapy
- surgical therapy
- family screening
High risk pt –> ICD
Arrhythmogenic RV Cardiomyopathy
RV myocardium replaced by fibro-fatty tissue
Progression
1. Myocardial stretch => Asymptomatic
2. Myocyte detachment and myocarditis => VT/ Sudden death, electric storm
3. Fibro-fatty replacement of cardiomyocytes => HF, sudden cardiac death
Sx - palpitation, syncope during exercise
ECG
- Epsilon waves (positive deflection buried in QRS)
- T wave inversion
- Broad QRS in V1-V3
CVD Management of Athletes
General: exercise prescription
Specific WPW => ablation Marfan => surgery Anomalous coronary artery => surgery Comotio cordis => protective clothes/ softballs Myocarditis => no sports for 3-6months
Cardiovascular adaptations to exercise
Electrical
- sinus bradycardia
- voltage criteria for LVH
- repolarisation anomalies
Structural
- incr LVWT 10-20%
- incr LV mass 40-65%
- incr LVED/ RVED 15%
- incr LA size 20%
Functional
- incr diastolic filling
- incr SV
Collectively cause 5x increase in CO
Adaptation - Adult, male, large BSA, endurance, black
Black Athlete’s heart
Typically asymptomatic
No FHx
ECG
- voltage criteria for LVH
- T wave inversion in V1-4
- ST segment elevation
TTE
- Maximal LVWT <=16mm in M and <=13mm in F
- concentric hypertrophy
- enlarged LVEDD
- normal diastolic function
Common combination for false positive diagnosis
Mild HCM + Athlete’s heart