example Q Flashcards
Which penicillin is considered a potential drug of choice for infections due to MSSA?
A. Penicillin G
B. Ticarcillin
C. Ampicillin
D. Nafcillin
E. Piperacillin
D
Which penicillin is considered a potential drug of choice for infections due to Pseudomonas aeruginosa?
A. Penicillin G
B. Ampicillin/sulbactam
C. Amoxicillin
D. Nafcillin
E. Piperacillin
E
Which of the following is NOT a general characteristic of β-lactam antibiotics?
A. Inhibition of cell wall synthesis
B. Long elimination half-lives
C. Primarily eliminated by the kidney
D. Bactericidal
E. Degradation by β-lactamase enzymes
B
True/False: A patient who developed a rash to penicillin can safely receive amoxicillin/clavulanate.
FALSE
Which cephalosporin is considered a potential drug of choice for infections due to MSSA?
A. Ceftazidime
B. Cefotetan
C. Cefazolin
D. Ceftolozane-Tazobactam
E. Cefonicid
c
Which cephalosporin does NOT have activity against Pseudomonas aeruginosa?
A. Ceftriaxone
B. Ceftazidime
C. Cefepime
D. Ceftolozane-Tazobactam
E. Ceftazidime-Avibactam
A
True/False: A patient who developed anaphylaxis to penicillin requiring ICU admission can safely receive any cephalosporin.
FALSE
True/False: Carbapenems are highly stable against many β-lactamase enzymes and are considered the drugs of choice for serious infections due to ESBL- and AmpC-producing bacteria.
TRUE
True/False: Meropenem-vaborbactam and imipenem-relebactam were developed to provide activity against KPC-producing Enterobacterales.
TRUE
Which carbapenem is co-formulated with cilastatin to prevent DHP degradation in the renal brush border and subsequent nephrotoxicity?
A.Doripenem
B. Meropenem
C. Ertapenem
D. Imipenem
E. All carbapenems are co-formulated with cilastatin
D
Which of the following antibiotics can be used in a patient who developed angioedema, hives and hypotension requiring ICU admission after an IM injection of penicillin?
A. Ampicillin
B. Meropenem
C. Ceftaroline
D. Aztreonam
E. None of the above
D
Which of the following antibiotics does NOT have activity against atypical bacteria (e.g., Legionella pneumophila)?
A. Azithromycin
B. Levofloxacin
C. Amoxicillin-clavulanate
D. Clarithromycin
E. Moxifloxacin
C
Which of the following antibiotics is least likely to interact with warfarin?
A. Azithromycin
B. Levofloxacin
C. Ciprofloxacin
D. Clarithromycin
E. Moxifloxacin
A
True/False:Vancomycin is the drug of choice for infections due to MRSA.
TRUE
Which antibiotic does NOT have activity against vancomycin-resistant Enterococcus faecalis (VRE)?
A. Quinupristin-dalfopristin
B. Linezolid
C. Daptomycin
D. Tedizolid
E. Oritavancin
A
Which of the following antibiotic-adverse effect combinations is INCORRECT?
Daptomycin – myopathy
Synercid – nephrotoxicity
Linezolid – thrombocytopenia
Vancomycin – Red man syndrome
Telavancin – QTc prolongation
Synercid – nephrotoxicity
True/False:All patients can receive the same aminoglycoside dose since there is little interpatient variability in Vd and Cl.
FALSE
Which of the following antibiotics does NOT have activity against Pseudomonas aeruginosa?
A. Cefepime
B. Ciprofloxacin
C. Tobramycin
D. Piperacillin
E. Ceftriaxone
E
Which of the following antibiotics does NOT cause nephrotoxicity?
A. Gentamicin
B. Telavancin
C. Vancomycin
D. Azithromycin
E. Nafcillin
D
Which antibiotic will interact with divalent/trivalent cations so that oral absorption is impaired potentially leading to clinical failure?
A. Oral levofloxacin
B. Oral doxycycline
C. Oral ciprofloxacin
D. Oral minocycline
E. All of the above
E
Which of the following antibiotics does NOT have activity against atypical bacteria (e.g., Legionella pneumophila)?
A. Azithromycin
B. Levofloxacin
C. Amoxicillin-clavulanate
D. Doxycycline
E. Moxifloxacin
C
True/False:Colistin is often used for the treatment of infections due to Gram-negative aerobes because it is not associated with serious adverse effects.
FALSE
Which of the following antibiotics will NOT interact with warfarin?
A. Trimethoprim-sulfamethoxazole
B. Metronidazole
C. Ciprofloxacin
D. Clindamycin
E. Clarithromycin
D
Which of the following antibiotics can be safely used during pregnancy?
A. Ampicillin
B. Levofloxacin
C. Doxycyclline
D. Metronidazole
E. Telavancin
A
Which of the following antibiotics does NOT require dosage adjustment in renal insufficiency?
A. Trimethoprim-sulfamethoxazole
B. Vancomycin
C. Gentamicin
D. Cefazolin
E. Nafcillin
E
Which of the following antibiotics is NOT associated with the development of nephrotoxicity?
A.Metronidazole
B.Vancomycin
C.Tobramycin
D.Colistin
E.Nafcillin
A
