Exam3 review

Question 1

Name Two properties of cells undergoing apoptosis

Question 2

What is the difference between executioner and initiator caspases

Question 3

Difference beteen malignant and benign tumors

Question 4

2 routes of oncogene activation

Answer 4

• Deletion/point mutation
  
  • hyperactive proteins made
  • ex. RAS 12 mutated from G–> V
• Regulatory mutation
  
  • Produce more normal proteins (promoter mutaiton)
• Gene amplification
  
  • several compies instead of 1 copy
• Chromosome rearrangement
  
  • New regulatory sequence added