Exam Two

Question 1

Views of Viral Pathogenesis

Answer 1

1. Predictable Outcome
2. Stochastic Events
3. Distinct Outcomes

Question 2

explain the “predictable outcome” view of viral pathogenesis + give example

Answer 2

infection can be viewed as a series of steps with a predictable outcome

example: mousepox has a predictable entry, path into the blood stream, and rash

Question 3

explain the “stochastic events” view of pathogenesis

Answer 3

infection can be viewed as a series of stochastic (random) events in which distribution of pathogen properties (genetic or expression differences) are selected for fitness by passing through bottlenecks in a tissue, cell, organ, host, or population