Exam Qs Flashcards

1
Q

What antisecretory and mucosa protectant can inhibit the metabolism of warfarin?

A

Cimetidine (enzyme inhibitor)

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2
Q

What is myositis?

A

Inflammation jn muscles

Weakness, swelling and pain are the most common myositis symptoms

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3
Q

What to do if a pt on methadone claims they have broken their methadone?

A

Advise them to obtain another prescription from their prescriber

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4
Q

Penicillin and breast feeding?

A

Considered compatible for BF but the infant should be monitored

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5
Q

What’s monitored under the clozapine pt monitoring service?

A

Leucocyte and neutrophil counts

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6
Q

Suitable pain killers for BF mothers?

A

Paracetamol (panadol)

Aspirin not suitable because of reyes syndrome (anadin)
Codeine no
Ibuprofen with caution

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7
Q

How long does it take for DMARD to show an effect?

A

2-3months

DMARDs have a slow onset of action

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8
Q

What laboratory tests are used to identify infectious disease?

A

C reactive protein e
Erythrocyte sedimentation ratr
Serum complement
White blood cell count

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9
Q

The legal requirements for a CD requisition are?

A
Signature of the receipient
Name of the recipient
Address of the recipient
Profession or occupation
Total quantity of drug
Purpose of requisition
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10
Q

What CD can a midwife obtain through supply orders?

A

Diamorphine
Morphine
Pethidine

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11
Q

The midwife requisition form must contain what info?

A
Name of the midwife
Occupation of the midwife
Name of the pt
Purpose of request
Total quantity
Signature of appropriate doctor
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12
Q

What is piroxicam?

A

NSAIDS

Piroxicam is particularly gastro toxic

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13
Q

What drugs interact with grapefruit juice?

A

Budesonide
Lercanidipine
Simvastatin
Tacrolimus

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14
Q

Zolendronic acid and pregnancy?

A

Not suitable in women of child bearing age

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15
Q

What is Promazine and pt advise on it?

A

An Antipsychotics

Protect skin form sunlight as susceptibile to burning

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16
Q

Treatment of severe CAP?

A
Co-amoxiclav 625mg TDS for 5 days.
Or IV 1.2g
With
Clarithromycin 500mg BD for 5 days
Or erythromycin in preg 500ng QDS for 5 days
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17
Q

How to measure pneumonia severity?

A
CRB65 score
C=confusion
R=Respiratory rate
B=BP below 90/60
65=age
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18
Q

Rare but what pain killer can cause nightmares? (Psychiatric side effects)

A

Tramadol

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19
Q

Sudafed decongestant tabs include?

A

Pseudoephedrine

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20
Q

Pseudoephedrine side effect on blood?

A

Increase blood glucose levels

So cautioned when selling to diabetics

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21
Q

Which vitamin deficiency may cause scurvy?

A

Vit C

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22
Q

Which vitamin when excessively ingested may cause overdosage symptoms such as rough skin, enlarged liver and increased serum alkaline phosphatase conc?

A

Vit A

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23
Q

Which vit needs to be avoided jn pregnancy?

A

Vit A

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24
Q

What act must you take in account when dealing with acetone?

A

Poisons Act 1972

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25
Q

Lithium and surgery?

A

Stop 24hrs before surgery

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26
Q

Which antiepileptc cause an increased risk of cleft palate if taken in the first trimester of preg?

A

Topiramate

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27
Q

After what time interval of drug administration would it be appropriate to assume that a rash is not due to the drug?

A

72hrs

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28
Q

Cough and cold preparations include antitussives, expectorant, decongestants and antihistamines. How long can they be used for childnre 6-12? And in adults?

A

5 days

5 to 7 days

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29
Q

What is UKDILAS?

A

UK drugs in lactation advisory service

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30
Q

What’s UKNPIS

A

National poisons information service

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31
Q

WHAT’S UKTIS?

A

teratology information service

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32
Q

Activated charcoal can be used to treat what drug overdose?

A
Carbamazepine
Dapsone
Phenobarbital
Quinine
Theophylline
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33
Q

Haemodialysis is used to treat what drugs poisoning?

A
Sodium valproate
Lithium
Salicylate
Phenobarbital
Methanol
Ethylene glycol
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34
Q

What antibiotic used for fistula ting CD cannot be used for more than 3 months? And its reason?

A

Metronidazole

Peripheral neuropathy

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35
Q

Norfloxacin’s cautionary and advisory labels?

A

Do not take milk, indigestion remedies or meds containing zinc or Iron 2hrs before or after taking this med
Should be taken on an empty stomacg
Keep taking this med until the course is finished unless told to stop

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36
Q

If a pt is taking linezolid, tedizolid and is vomiting, will you refer?

A

No, a common side effect. Treat OTC

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37
Q

MHRA warning on Febuxostat?

A

Serious hypersensitivity reactions Inc. Stevens johnsons

Increased risk of cardiovascular death in pts with a hisotyr of major CV disease

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38
Q

Which NSAID has intermediate risk of GI events?

A

Indomethacin

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39
Q

How to reduce ICS?

A

Every 3 months, decreasing the dose by 30-50% each time

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40
Q

When do you offer the first dose of Boostrix-IPV (for diphtheria) to a preg lady?

A

From the 16th week of preg

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41
Q

Side effect of trastuzumab?

A

Peripheral neuropathy

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42
Q

Who is exempt from paying NHS flu vaccine?

A

Third trimester of preg

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43
Q

Interaction between naproxen and prednisolone?

A

Increased bleeding risk

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44
Q

Symptoms of benign prostatic hyperplasia?

A
Frequent or urgent need to urinate
Nocturia
Difficulty starting urination
Weak urine stream
Dribble at the end of piss
Inability to complete
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45
Q

Which statin interacts with amiodarone?

A

Fluvastatin
Atorvastatin
Simvastatin

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46
Q

When to take rosuvastatin?

A

Any time of the day as it has long duration of action

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47
Q

Which Antipsychotics are least likely to cause weight gai?

A
Aripiprazole
Amisulpride
Haloperidol
Sulpiride
Trifluoperazine
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48
Q

Common side effect of donepezil?

A

Aggression; agitation; appetite decreased; common cold; diarrhoea; dizziness; fatigue; gastrointestinal disorders; hallucination; headache; injury; muscle cramps; nausea; pain; skin reactions; sleep disorders; syncope; urinary incontinence; vomiting

49
Q

From what age does risk of thrombosis increase?

A

Above 35

50
Q

How to take methotrexate tabs?

A

To maximise the absorption, methotrexate should be taken on an empty stomach (an hour or 2hrs after food)
However, if experiencing GI discomfort, can be taken with or after food

51
Q

What is vit b6?

A

Pyridoxine

52
Q

What is Terbinafine and its most important side effects?

A

Antifungal like amorolfine, flucytosine, Griseofulvin

Liver toxicity
Serious skin reaction

53
Q

How to store insulin cartilage?

A

Stored in fridge until opened

Cartilage in use or spare carried around should be stored below 30 and protected from sun

54
Q

Methyldopa’s cautionary advice and label?

A

This med may make you sleepy. If this happens, do not drive ur use tools or machines

Do not stop taking this med unless the Dr tells you to stop

55
Q

What is raynaud’s disease?

A

Causes some of the areas of the body esp fingers and toes to feel numb and cold in response to cold temperature and stress
Small arteries that supply blood to the skin narrows and limit blood circulation

56
Q

How to manage raynaud’s disease?

A

Nifedipine 5mg TDS increase up to 20mg TDS

57
Q

What kind of muscle complaints does montelukast have?

A

Hyperkinesia (muscle spasm)

58
Q

What is manual therapy and when is it used?

A

A physical therapy used to treat musculoskeletal Pain and disability
Kneading and manipulation of muscles and joint

59
Q

What’s a potent dopamine receptor used under specialist for PD?

A

Apomorohine

60
Q

What drugs cause grey baby syndrome?

A

Chloramphenicol

61
Q

What antibiotic can cause eye dristurbance?

A

Ethambutol

62
Q

Which one is mote sedating? Methadone or Buprenorphine?

A

Methadone

63
Q

Lithium and headache?

A

Stop treatment as might be intracranial Hypertension

64
Q

What size does Lidocaine come in?

A

10g

65
Q

What’s chloroform used as when added to products?

A

Preservative agent

66
Q

What meds need a designated special container?

A

Reagents containing an integral means of application
Meds containing coal tar
Meds that are hygroscopic
Meds that are sterile

67
Q

Which antibiotic has a severe reaction with ciclosporin?

A

Clari and erithro

NOT
Metronidazole
So in H. Pylori use metronidazole

68
Q

Which antibiotic has a severe reaction with ciclosporin?

A

Clari and erithro

NOT
Metronidazole
So in H. Pylori use metronidazole

69
Q

What drug will need dose adjustment when used with orlistat?

A
Antidiabetic
Antihyoertensives
Anticholestoraemia
Amiodaribe
Levithyroxine
Antiepileptcs = increased risk of convulsion
70
Q

Pt advice on orlistat?

A

Take multivitamin at bedtime

71
Q

What information source can be used to look up different countries drug names?

A

Martindale: the complete drug reference

72
Q

How to apply panciclovir cream for cold sore?

A

Every 2hrs during waking hours

73
Q

What is eumovate cream?

A

0.05% clobetasone

74
Q

What is eumovate cream?

A

0.05% clobetasone

75
Q

What is Trazodone?

A

Serotonin receptor antagonists and reuptake inhibitors SARI

76
Q

Pts who have severe eriphrral vascular disease should avoid what drug?

A

Atenolol

77
Q

Maximus CD treatment duration? Recommended?

A

30 days

78
Q

What must pts do to request access to data about themselves gotm the PMR?

A

Might have to pay a fee

79
Q

Empty stomach means when?

A

1hr before and 2hrs after food

80
Q

Which one is bettwen jn children, live attenuated intranasal vaccine or inactivated IM vaccine?

A

Live attenuated intranasal vaccine has shown more protection

81
Q

What does NICE guidelines do?

A

Develop recommendations about the appropriate treatment and care of people with specific diseases and conditions within the NHS

82
Q

Where to report large spillage of cytotoxic drugs where staff are exposed to the drug?

A

Report under the reporting of injuries, disease and dangerous occurrence regulations (RIDDOR)

83
Q

What is the Cochrane library?

A

A collection to database containing systemic reviews

84
Q

What best described clinical audit?

A

Checking practice against known standards

85
Q

What p value indicates that the findings are statistically significant?

A

0.02

86
Q

What disease would it be if greyish white spots in the mouth?

A

Measles

87
Q

What drugs increases the risk of UTI?

A

Canagliflozin

88
Q

What’s Boostrix IPV injection for?

A

Wooping cough

89
Q

What needs to be in the vet prescription? Under the cascade

A

The words keep out of reach of children
Address of owner
Address of pharmacy
Identification of species

90
Q

What antibiotics are associated with C difficile resistance?

A

Cefaclor
Ciprofloxacin
Clindamycin
Co amoxiclav

91
Q

What antibiotics are not associated with C diff resistance?

A

Macrolides

92
Q

When to give folic acid for preg?

A

Pre conception and until week 12 of Preganancy

93
Q

Hydroxychloroquine side effect?

A

Visual disturbances

94
Q

How many tea spoons of sugar do you have to give for Hypoglycaemia?

A

3-4

95
Q

Which containers used in preparing products should have air added to it to allow easy removal of the liquid inside?

A

Sealed vial

96
Q

Max daily dose of omeprazole?

A

OD

97
Q

Max day application frequency of aciclovir?

A

Five times a day at 4hrs interval

98
Q

Max application frequency of hydrocortisone cream?

A

BD

99
Q

Max daily dose of pantoprazole?

A

OD 20mg

100
Q

Electrolyte disturbances that trimethoprim can cause?

A

Hyperkalaemia

101
Q

How long after taking ulpristal should a women wait before BF again?

A

One week

102
Q

Which js not a legal requirement in NHS prescription?
Dose
Formuaktiin
Strength of meds

A

Dose

103
Q

Lidocaine oral gel for teething should not be used more than?

A

6 times a day

104
Q

Nicotinell patch should be removed prior to what test?

A

MRI

105
Q

Which two antiepileptcs are the safest jn preg?

A

Lamotrigine and levetiracetam

106
Q

Capecitabine, what is it?

A

Antimetabolites

107
Q

What best described meds rec?

A

The process of creating an accurate list of pts current meds and comparing this to those in the pts meds record with the goal of providing the pt with the correct meds

108
Q

Insulin can cause lipodystrophy as well as?

A

Cutaneous amyloudosis

109
Q

What antiemetic have a small increased risk of oral clefts?

A

Ondansetron

110
Q

What drug used in asthma can lead to development of a stutter?

A

Montelukast

111
Q

What drug should defo be avoidded in antibiotic associated colitis?

A

Loperamide

112
Q

How often should an audit be undertaken for POMV and POMVPS supplies?

A

1yr

113
Q

What does change in voices indicate?

A

Severe allergic reaction

114
Q

When to use aspirin in preg?

A

For prophylaxis of eclampsia

Between 12wjs to 28

115
Q

Are Buprenorphine patches licensed for treatment of opioid dependence?

A

No

116
Q

Within how many hours does MHRA class 2 drug alert need to be sorted?

A

Within 48hrs

117
Q

Which insulin needs to be prescribed by brand?

A

Lispro

118
Q

What vaccine would a 12 Yr child have which also has a follow up booster dose?

A

Human papilloma virus

119
Q

Amphetamine and Methylphenidate interaction?

A

Cardiac arrhythmia