Exam Qs Flashcards
1
Q
What antisecretory and mucosa protectant can inhibit the metabolism of warfarin?
A
Cimetidine (enzyme inhibitor)
2
Q
What is myositis?
A
Inflammation jn muscles
Weakness, swelling and pain are the most common myositis symptoms
3
Q
What to do if a pt on methadone claims they have broken their methadone?
A
Advise them to obtain another prescription from their prescriber
4
Q
Penicillin and breast feeding?
A
Considered compatible for BF but the infant should be monitored
5
Q
What’s monitored under the clozapine pt monitoring service?
A
Leucocyte and neutrophil counts
6
Q
Suitable pain killers for BF mothers?
A
Paracetamol (panadol)
Aspirin not suitable because of reyes syndrome (anadin)
Codeine no
Ibuprofen with caution
7
Q
How long does it take for DMARD to show an effect?
A
2-3months
DMARDs have a slow onset of action
8
Q
What laboratory tests are used to identify infectious disease?
A
C reactive protein e
Erythrocyte sedimentation ratr
Serum complement
White blood cell count
9
Q
The legal requirements for a CD requisition are?
A
Signature of the receipient Name of the recipient Address of the recipient Profession or occupation Total quantity of drug Purpose of requisition
10
Q
What CD can a midwife obtain through supply orders?
A
Diamorphine
Morphine
Pethidine
11
Q
The midwife requisition form must contain what info?
A
Name of the midwife Occupation of the midwife Name of the pt Purpose of request Total quantity Signature of appropriate doctor
12
Q
What is piroxicam?
A
NSAIDS
Piroxicam is particularly gastro toxic
13
Q
What drugs interact with grapefruit juice?
A
Budesonide
Lercanidipine
Simvastatin
Tacrolimus
14
Q
Zolendronic acid and pregnancy?
A
Not suitable in women of child bearing age
15
Q
What is Promazine and pt advise on it?
A
An Antipsychotics
Protect skin form sunlight as susceptibile to burning
16
Q
Treatment of severe CAP?
A
Co-amoxiclav 625mg TDS for 5 days. Or IV 1.2g With Clarithromycin 500mg BD for 5 days Or erythromycin in preg 500ng QDS for 5 days
17
Q
How to measure pneumonia severity?
A
CRB65 score C=confusion R=Respiratory rate B=BP below 90/60 65=age
18
Q
Rare but what pain killer can cause nightmares? (Psychiatric side effects)
A
Tramadol
19
Q
Sudafed decongestant tabs include?
A
Pseudoephedrine
20
Q
Pseudoephedrine side effect on blood?
A
Increase blood glucose levels
So cautioned when selling to diabetics
21
Q
Which vitamin deficiency may cause scurvy?
A
Vit C
22
Q
Which vitamin when excessively ingested may cause overdosage symptoms such as rough skin, enlarged liver and increased serum alkaline phosphatase conc?
A
Vit A
23
Q
Which vit needs to be avoided jn pregnancy?
A
Vit A
24
Q
What act must you take in account when dealing with acetone?
A
Poisons Act 1972
25
Lithium and surgery?
Stop 24hrs before surgery
26
Which antiepileptc cause an increased risk of cleft palate if taken in the first trimester of preg?
Topiramate
27
After what time interval of drug administration would it be appropriate to assume that a rash is not due to the drug?
72hrs
28
Cough and cold preparations include antitussives, expectorant, decongestants and antihistamines. How long can they be used for childnre 6-12? And in adults?
5 days
5 to 7 days
29
What is UKDILAS?
UK drugs in lactation advisory service
30
What's UKNPIS
National poisons information service
31
WHAT'S UKTIS?
teratology information service
32
Activated charcoal can be used to treat what drug overdose?
```
Carbamazepine
Dapsone
Phenobarbital
Quinine
Theophylline
```
33
Haemodialysis is used to treat what drugs poisoning?
```
Sodium valproate
Lithium
Salicylate
Phenobarbital
Methanol
Ethylene glycol
```
34
What antibiotic used for fistula ting CD cannot be used for more than 3 months? And its reason?
Metronidazole
| Peripheral neuropathy
35
Norfloxacin's cautionary and advisory labels?
Do not take milk, indigestion remedies or meds containing zinc or Iron 2hrs before or after taking this med
Should be taken on an empty stomacg
Keep taking this med until the course is finished unless told to stop
36
If a pt is taking linezolid, tedizolid and is vomiting, will you refer?
No, a common side effect. Treat OTC
37
MHRA warning on Febuxostat?
Serious hypersensitivity reactions Inc. Stevens johnsons
Increased risk of cardiovascular death in pts with a hisotyr of major CV disease
38
Which NSAID has intermediate risk of GI events?
Indomethacin
39
How to reduce ICS?
Every 3 months, decreasing the dose by 30-50% each time
40
When do you offer the first dose of Boostrix-IPV (for diphtheria) to a preg lady?
From the 16th week of preg
41
Side effect of trastuzumab?
Peripheral neuropathy
42
Who is exempt from paying NHS flu vaccine?
Third trimester of preg
43
Interaction between naproxen and prednisolone?
Increased bleeding risk
44
Symptoms of benign prostatic hyperplasia?
```
Frequent or urgent need to urinate
Nocturia
Difficulty starting urination
Weak urine stream
Dribble at the end of piss
Inability to complete
```
45
Which statin interacts with amiodarone?
Fluvastatin
Atorvastatin
Simvastatin
46
When to take rosuvastatin?
Any time of the day as it has long duration of action
47
Which Antipsychotics are least likely to cause weight gai?
```
Aripiprazole
Amisulpride
Haloperidol
Sulpiride
Trifluoperazine
```
48
Common side effect of donepezil?
Aggression; agitation; appetite decreased; common cold; diarrhoea; dizziness; fatigue; gastrointestinal disorders; hallucination; headache; injury; muscle cramps; nausea; pain; skin reactions; sleep disorders; syncope; urinary incontinence; vomiting
49
From what age does risk of thrombosis increase?
Above 35
50
How to take methotrexate tabs?
To maximise the absorption, methotrexate should be taken on an empty stomach (an hour or 2hrs after food)
However, if experiencing GI discomfort, can be taken with or after food
51
What is vit b6?
Pyridoxine
52
What is Terbinafine and its most important side effects?
Antifungal like amorolfine, flucytosine, Griseofulvin
Liver toxicity
Serious skin reaction
53
How to store insulin cartilage?
Stored in fridge until opened
| Cartilage in use or spare carried around should be stored below 30 and protected from sun
54
Methyldopa's cautionary advice and label?
This med may make you sleepy. If this happens, do not drive ur use tools or machines
Do not stop taking this med unless the Dr tells you to stop
55
What is raynaud's disease?
Causes some of the areas of the body esp fingers and toes to feel numb and cold in response to cold temperature and stress
Small arteries that supply blood to the skin narrows and limit blood circulation
56
How to manage raynaud's disease?
Nifedipine 5mg TDS increase up to 20mg TDS
57
What kind of muscle complaints does montelukast have?
Hyperkinesia (muscle spasm)
58
What is manual therapy and when is it used?
A physical therapy used to treat musculoskeletal Pain and disability
Kneading and manipulation of muscles and joint
59
What's a potent dopamine receptor used under specialist for PD?
Apomorohine
60
What drugs cause grey baby syndrome?
Chloramphenicol
61
What antibiotic can cause eye dristurbance?
Ethambutol
62
Which one is mote sedating? Methadone or Buprenorphine?
Methadone
63
Lithium and headache?
Stop treatment as might be intracranial Hypertension
64
What size does Lidocaine come in?
10g
65
What's chloroform used as when added to products?
Preservative agent
66
What meds need a designated special container?
Reagents containing an integral means of application
Meds containing coal tar
Meds that are hygroscopic
Meds that are sterile
67
Which antibiotic has a severe reaction with ciclosporin?
Clari and erithro
NOT
Metronidazole
So in H. Pylori use metronidazole
68
Which antibiotic has a severe reaction with ciclosporin?
Clari and erithro
NOT
Metronidazole
So in H. Pylori use metronidazole
69
What drug will need dose adjustment when used with orlistat?
```
Antidiabetic
Antihyoertensives
Anticholestoraemia
Amiodaribe
Levithyroxine
Antiepileptcs = increased risk of convulsion
```
70
Pt advice on orlistat?
Take multivitamin at bedtime
71
What information source can be used to look up different countries drug names?
Martindale: the complete drug reference
72
How to apply panciclovir cream for cold sore?
Every 2hrs during waking hours
73
What is eumovate cream?
0.05% clobetasone
74
What is eumovate cream?
0.05% clobetasone
75
What is Trazodone?
Serotonin receptor antagonists and reuptake inhibitors SARI
76
Pts who have severe eriphrral vascular disease should avoid what drug?
Atenolol
77
Maximus CD treatment duration? Recommended?
30 days
78
What must pts do to request access to data about themselves gotm the PMR?
Might have to pay a fee
79
Empty stomach means when?
1hr before and 2hrs after food
80
Which one is bettwen jn children, live attenuated intranasal vaccine or inactivated IM vaccine?
Live attenuated intranasal vaccine has shown more protection
81
What does NICE guidelines do?
Develop recommendations about the appropriate treatment and care of people with specific diseases and conditions within the NHS
82
Where to report large spillage of cytotoxic drugs where staff are exposed to the drug?
Report under the reporting of injuries, disease and dangerous occurrence regulations (RIDDOR)
83
What is the Cochrane library?
A collection to database containing systemic reviews
84
What best described clinical audit?
Checking practice against known standards
85
What p value indicates that the findings are statistically significant?
0.02
86
What disease would it be if greyish white spots in the mouth?
Measles
87
What drugs increases the risk of UTI?
Canagliflozin
88
What's Boostrix IPV injection for?
Wooping cough
89
What needs to be in the vet prescription? Under the cascade
The words keep out of reach of children
Address of owner
Address of pharmacy
Identification of species
90
What antibiotics are associated with C difficile resistance?
Cefaclor
Ciprofloxacin
Clindamycin
Co amoxiclav
91
What antibiotics are not associated with C diff resistance?
Macrolides
92
When to give folic acid for preg?
Pre conception and until week 12 of Preganancy
93
Hydroxychloroquine side effect?
Visual disturbances
94
How many tea spoons of sugar do you have to give for Hypoglycaemia?
3-4
95
Which containers used in preparing products should have air added to it to allow easy removal of the liquid inside?
Sealed vial
96
Max daily dose of omeprazole?
OD
97
Max day application frequency of aciclovir?
Five times a day at 4hrs interval
98
Max application frequency of hydrocortisone cream?
BD
99
Max daily dose of pantoprazole?
OD 20mg
100
Electrolyte disturbances that trimethoprim can cause?
Hyperkalaemia
101
How long after taking ulpristal should a women wait before BF again?
One week
102
Which js not a legal requirement in NHS prescription?
Dose
Formuaktiin
Strength of meds
Dose
103
Lidocaine oral gel for teething should not be used more than?
6 times a day
104
Nicotinell patch should be removed prior to what test?
MRI
105
Which two antiepileptcs are the safest jn preg?
Lamotrigine and levetiracetam
106
Capecitabine, what is it?
Antimetabolites
107
What best described meds rec?
The process of creating an accurate list of pts current meds and comparing this to those in the pts meds record with the goal of providing the pt with the correct meds
108
Insulin can cause lipodystrophy as well as?
Cutaneous amyloudosis
109
What antiemetic have a small increased risk of oral clefts?
Ondansetron
110
What drug used in asthma can lead to development of a stutter?
Montelukast
111
What drug should defo be avoidded in antibiotic associated colitis?
Loperamide
112
How often should an audit be undertaken for POMV and POMVPS supplies?
1yr
113
What does change in voices indicate?
Severe allergic reaction
114
When to use aspirin in preg?
For prophylaxis of eclampsia
| Between 12wjs to 28
115
Are Buprenorphine patches licensed for treatment of opioid dependence?
No
116
Within how many hours does MHRA class 2 drug alert need to be sorted?
Within 48hrs
117
Which insulin needs to be prescribed by brand?
Lispro
118
What vaccine would a 12 Yr child have which also has a follow up booster dose?
Human papilloma virus
119
Amphetamine and Methylphenidate interaction?
Cardiac arrhythmia
