Exam II: Neurosurgical Anesthesia Flashcards
Space-occupying ____ and ↑’d ____ volume
[Challenges of a Craniotomy]
lesions, intracranial
Closed non-expandable___ ___“closed box”
-Brain tissue (___), blood (___) and CSF (___)
[Challenges of a Craniotomy]
cranial vault
80%, 12%, 8%
Altered vasoreactivity and ____
[Challenges of a Craniotomy]
autoregulation
Control of___, ___, CPP, ICP and brain swelling
[Challenges of a Craniotomy]
CBF, CBV
Varying levels of ___stimulation occur
-Scalp, skull, dura elicit ___ noxious stimuli
-___tissue almost free from nocioceptive nerve tissue.
[Challenges of a Craniotomy]
noxious
increased
Brain
Unfamiliar monitoring , HOB away from ___
[Challenges of a Craniotomy]
anesthetist
Access to ___is not readily available
[Challenges of a Craniotomy]
airway
Cushing’s reflex: ___=___=___
*Respect ↑’d ICP ability to damage___
[Challenges of a Craniotomy]
↑ICP =↑ HTN = ↓ HR
brain
Flow & ___ are coupled:
___ also ___ & ___
___can alter this coupling
[Challenges of a Craniotomy]
metabolism
↓CMRO2 also ↓CBF & ICP
Drugs
Blood loss & ___can change rapidly
[Challenges of a Craniotomy]
hemodynamics
___ and vasodilators are usually inline and ready for immediate titration.
[Challenges of a Craniotomy]
Vasoconstrictors
Goal is “___” brain not a “___” brain
[Challenges of a Craniotomy]
relaxed, tight
___soaked gauze utilized
[Challenges of a Craniotomy]
Epinephrine
___ surgery
[Challenges of a Craniotomy]
Tedious
Intense noxious stimulation at___ and ___ with little in the ___
[Challenges of a Craniotomy]
beginning, end, middle
Head ROM is fixed due to ___ ___.
[Challenges of a Craniotomy]
cranial pinning
Glucose is the ___ substrate of metabolism
[Metabolism of the Brain]
primary
____worsens hypoxic injury
[Metabolism of the Brain]
Hypoglycemia
The metabolic rate of the brain is measured in ___ ___
[Metabolism of the Brain]
oxygen consumption
Cerebral metabolic rate of oxygen consumption-___
[Metabolism of the Brain]
CMRO2
Adult human brain = ___-___ gms
[Cerebral Blood Flow]
1300-1400
___-___ ml of blood per minute (___/___)
Around ___of total cardiac output
[Cerebral Blood Flow]
650-700, 700/5000
14%
CNS has a ___-___coupling ensuring a supply and demand match:
Increased brain metabolic activity increases ___&___
[Cerebral Blood Flow]
flow-metabolism
CBF & ICP
The brain can increase flow as much as ___-___% of cardiac output
[Cerebral Blood Flow]
15-20