Exam II Anesthesia for Laparoscopic Endoscopic Procedures Flashcards

1
Q

Advantages of laparoscopic procedures (7)

A
  • less tissue trauma
  • reduced postop pain
  • shorter hospital stays
  • more rapid return to normal activities
  • significant cost savings
  • less potential for postoperative complications such as development of an ileus
  • improved cosmetic results
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2
Q

Indications for laparoscopic procedures are an ever-growing list of procedures including:

A
  • cholecystectomy
  • appendectomy
  • Fundoplication
  • inguinal hernia repair
  • GYN: tubal ligation, myomectomy, assisted hysterectomy, oophorectomy, lysis of adhesions, fulgartion of endometriosis, removal of ectopic pregnancies/tubal repair, diagnostic procedures, ovarian cystectomy
  • colon resection
  • splenectomy
  • nephrectomy
  • liver biopsy
  • diastasis repair
  • bariatric surgeries
  • undescended testicles
  • prostatectomy
  • cystectomy
  • robotic procedures
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3
Q

Lap absolute contraindications (6)

A
  • bowel obstruction
  • ileus
  • peritonitis
  • intraperitoneal hemorrhage
  • diaphragmatic hernia
  • severe cardiopulmonary disease (CHF)
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4
Q

Lap relative CIs: (8)

A
  • extremes of weight
  • inflammatory bowel disease
  • presence of large abdominal masses
  • advanced Intra-uterine pregnancy
  • increased ICPs
  • VP shunts
  • coagulopathy
  • previous abdominal surgeries with adhesions
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5
Q

Uterus remains in the _____ during the _____ _____ to allow safe insertion of the Veress needle through the _____

A

Pelvis
First trimester
Umbilicus

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6
Q

The enlarged uterus after the ____ week interferes with _____

A

23rd
Visualization

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7
Q

Closely monitor _____ in pregnant patients to maintain slightly _____ state in mother

A

PaCO2
Alkalotic

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8
Q

Place pregnant patient in ____-_____ _____-______ displacement

A

30-degree
Left-uterine

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9
Q

Limit intraperitoneal pressures in pregnant women to ____ ____

A

12 mmHg

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10
Q

Monitor fetal ____ ____ throughout with ______ ultrasound

A

Heart rate
Transvaginal

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11
Q

FOUR potential causes of major physiologic changes during laparoscopy we need to know:

A
  1. Creation of the pneumoperitoneum
  2. Potential for systemic absorption of CO2
  3. Initial trendelenburg position
  4. Reverse trendelenburg position
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12
Q

What is a pneumoperitoneum?

A

Insufflation of the peritoneal cavity with CO2 (air, N2O, helium, and O2)

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13
Q

_____ and _____ caused greater hemodynamic depression with pneumoperitoneum if embolized into venous vasculature and caused death at much smaller volumes

A

Helium and argon

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14
Q

____ is the safest gas to use with pneumoperitoneum

A

CO2

Be sure the tank is truly only CO2 bc it can be combined with O2 and still have the same PIN index. If the tank has greater than 7% CO2 it has the same PIN index. Potential for combustion

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15
Q

Characteristics of pneumoperitoneum: doesn’t support ______

A

Combustion

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16
Q

Characteristics of pneumoperitoneum: Blood solubility enhances ____ _____, decreasing risk of ____ _____

A

Tissue diffusion
Gas emboli

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17
Q

Characteristics of pneumoperitoneum: More pain due to _______ irritation

A

Diaphragmatic

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18
Q

Characteristics of pneumoperitoneum: Hyper_____, _____ acidosis, cardiac ______

A

Hypercarbia
Respiratory acidosis
Cardiac dysrhythmias

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19
Q

Advantage of pneumoperitoneum: separates the ______ _____ from the _____ of the peritoneal cavity to optimize ______ and access

A

Abdominal wall
Contents
Visualization

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20
Q

Disadvantage of pneumoperitoneum: limits surgeon’s freedom of ______, choice of _____, involves risk of significant complications r/t use of _____

A

Movement
Instruments
CO2

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21
Q

Procedure for creating a pneumoperitoneum: inject LA into the _____ area

A

Umbilical

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22
Q

Procedure for creating a pneumoperitoneum: Insert _____ _____ via anesthetized area into peritoneal cavity

A

Veress needle

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23
Q

Procedure for creating a pneumoperitoneum: Insufflate the cavity with CO2 at a pressure less than ___ ____ (___)

A

19 mmHg (3L)

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24
Q

Procedure for creating a pneumoperitoneum: Once distended, insufflator placed in _____ mode to maintain pneumoperitoneum at ____ ____

A

Automatic mode
12 mmHg

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25
Procedure for creating a pneumoperitoneum: Intraabdominal pressure is maintained between __-__ mmHg
12-15 mmHg This is an important time in the procedure as it is during this time that the patient is at highest risk for serious complications
26
Retroperitoneoscopic adrenalectomy - small cavity created in the _____ _____ and CO2 insufflation pressure to __-__ mmHg
Lumbodorsay lascia 15-20 mmHg
27
Traumatic injuries: unintentional injuries to abdominal organs, insertion of ____ ____, and ____.
Veress needle and trocars (Aorta/vascular, intestinal walls, urinary tract)
28
Traumatic injuries: unintentional injuries to abdominal organs, insertion of ____ ____, and ____.
Veress needle and trocars (Aorta/vascular, intestinal walls, urinary tract)
29
Traumatic injuries: More than ___ of complications occur during entry and insertion of trocars
50%
30
30-50% of injuries ____ diagnosed intraoperatively resulting in mortality of __-___
Aren’t 3.5-5%
31
Traumatic injuries: Massive hemorrhage due to _____ of _____ or _____ of _____ with stretching of pre-existing splenic adhesions
Penetration of vessels Rupture of spleen
32
Traumatic injuries: Intestinal injuries __-__% of surgeries with less than __% of injuries recognized at the time of surgery including (4)
0.3-0.5% 50% Including: peritonitis, sepsis, resp failure, multi-organ failure
33
Traumatic injuries: _____ _____ injury occurs in 0.5-8.3% of cases
Urinary tract
34
Traumatic injuries: _____ ____ to check for urinary structure damage or looking for ____ in catheter
Methylene blue Blood
35
Risk factors for injuries during pneumoperitoneum: (7)
- body Habitus - anatomic anomalies - prior surgeries - surgical skill - degree of abdominal elevation during trocar placement - patient position - volume of gas insufflation
36
_____ _____ due to improper placement of the needle between facial planes in the muscle
Subcutaneous emphysema
37
Subcutaneous emphysema can cause ____ issues
Airway
38
With SC emphysema, consider leaving patient ____ until _____
Intubated Reabsorbed
39
Physiologic changes associated with pneumoperitoneum depend on: (8)
- intraabdominal pressure attained - volume of CO2 absorbed - patient position - patient age, comorbidities - patient’s intravascular volume - ventilators technique - surgical conditions/time - anesthetic agents used
40
Physiologic changes associated with pneumoperitoneum: increased ____, ____, ____ and initial increase in _____, and initial decrease in _____
Increased SVR, MAP, HR, initial increase in CVP, and initial decrease in cardiac index
41
Physiologic changes associated with pneumoperitoneum: initial increase of CVP may have decrease due to ____ ____, _____ will have greater effect than pneumo
Other factors Position
42
Physiologic changes associated with pneumoperitoneum: initial decrease in cardiac index (50% baseline - proportional to the ____ ____ achieved)
IA pressure
43
Initially CVP increases due to to _____ of abdominal _____ _____
Redistribution Blood volume
44
Ultimately, ____ ____ decreases, but filling pressures increase. This is related to the transmitted pressure into the ____ _____. Don’t trust filling pressures to correlate to _____.
Venous return Thorax cavity Volume
45
Elevated levels of _____ (___) early and increased _____ later cause increased SVR
Vasopressin (ADH) Catecholamines
46
Elevated Vasopressin: Higher catecholamines r/t pressure of __ ____ v. __ ____ [Physiologic changes associated with pneumoperitoneum]
20 torr v. 10 torr
47
Decreased CO is r/t decreased ____ ____, r/t _____ and ____ ______ causing reduced stroke volume [Physiologic changes associated with pneumoperitoneum]
Venous return Pneumo Reverse trendelenburg
48
It is not unusual for CO to attempt to maintain r/t increase in ____ [Physiologic changes associated with pneumoperitoneum]
HR
49
It is reported that decreases in CO is only r/t intraabdominal pressures that exceed ___ torr or __ torr if GYN procedures [Physiologic changes associated with pneumoperitoneum]
16 20
50
The decrease in CO can be minimized to a 20% drop if ____ are _____ and the patient is ______ versus a 50% drop in control patients [Physiologic changes associated with pneumoperitoneum]
Legs are wrapped Normovolemic
51
Decreased stroke volume is r/t decreased ____ ____ [Physiologic changes associated with pneumoperitoneum]
Venous return
52
Decreased stroke volume can be offset by: (3) [Physiologic changes associated with pneumoperitoneum]
- perioperative hydration - changes in pt position - compression stockings
53
______ with initial insufflation [Physiologic changes associated with pneumoperitoneum]
Bradycardia
54
_____ ____ with high pressure insufflation [Physiologic changes associated with pneumoperitoneum]
Prolonged QT
55
Physiologic changes associated with pneumoperitoneum: increased myocardial _____ _____ initially followed by sustained decrease in _____
Filling pressures Preload (decreased venous return)
56
Physiologic changes associated with pneumoperitoneum: increased _____ blood flow and _____ pressure - hyperventilation does not effect however hypo ventilation makes it worse
Cerebral Intracranial
57
Physiologic changes associated with pneumoperitoneum: decreased ____, _____, and _____ blood flow
Renal, portal, and splanchnic (decreased GFR, UOP, and creatinine clearance)
58
Increased filling pressures lead to compression of abd ____ ____ which pushes blood back into ____ circulation, as well as increased “_____” without increased ______
Venous beds Central Numbers Volume
59
The combo of _____ of ___ mmHg and ____ position increases ICP 150%
IAP of 16 mmHg Trendelenburg
60
Increased ____ pressure and impaired venous drainage of the lumbar venous plexus were causative in the reduction in the absorption of ____ during insufflation
IVC CSF [The combination of an IAP of 16 mm Hg and Tburg position increased ICP 150%.]
61
Renal vein flow, UOP, and creatinine clearance decreased more than when the IAP was greater than ____ _____
15 mmHg
62
Portal blood flow decreases by ____ with an IAP of 14 mmHg
53%
63
___ ____ also reduced total hepatic, hepatic arterial, and portal venous blood flow
Reverse trendelenburg
64
Splanchnic circulation decreases dependent on ____. ___ mmHg only has minimal effects, ___ mmHg mechanically compresses the mesenteric vasculature and decreases intestinal ____. _____ release causes mesenteric artery constriction.
IAP 7 mmHg 14 mmHg pH ADH
65
Physiologic changes associated with pneumoperitoneum: decreased pulm _____ - increase in peak airway pressure due to ______ shifting upward
Compliance Diaphragm
66
Physiologic changes associated with pneumoperitoneum: reduced lung volumes: (4)
- decreased vital capacity - decreased FRC - atelectasis - hypoxemia d/t vent/perf mismatching in obese/pulm disease patients (not healthy pts)
67
Physiologic changes associated with pneumoperitoneum: ______ - ____ increased 0-30% from absorption
Hypercarbia CO2
68
Lap chole postop: sustained decreases in (3) for 24 hours postop
- forced vital capacity - peak expiratory flow - force expiratory volume in 1 second (FEV1) However these changes are only 50% of the changes that occur with open chole
69
Physiologic changes associated with pneumoperitoneum: CO2 Absorption - may result in ______
Acidosis
70
Respiratory acidosis - can increase ______ to offset
MV
71
Maximum absorption of CO2 at ____ ____ pressure
10 mmHg
72
PaCO2 reaches plateau approx. ____ ____ after start of insufflation
40 mins
73
Physiologic changes associated with pneumoperitoneum trendelenburg: ___-____ _____ allows small bowel and colon to move out of the pelvis and minimize needle or trocar perforation
10-20 degrees
74
Physiologic changes associated with pneumoperitoneum Trendelenburg: increases ____ ____ and increases ____
Venous return and CO
75
Physiologic changes associated with pneumoperitoneum Trendelenburg: reduces lung capacity due to weight of _____ ____ on _____ (decreased ___)
Abdominal contents on diaphragm (decreased FRC)
76
Physiologic changes associated with pneumoperitoneum Trendelenburg: inadvertent ____ _____ _____ intubation when the lung and carina is displaced _____
Right Mainstem bronchial intubation Cephalad
77
Increased ____ _____, increased ____ _____ volume, Increased _____ increased ____ _____ work: the combo of these may lead to MI if pt is at risk
Venous return Systolic heart volume SVR Ventricular systolic work
78
Physiologic changes associated with pneumoperitoneum Trendelenburg: increase in intraabdominal pressure and gravity increase risk of ____ of ____ contents. Pts needs ____ ____.
Aspiration Gastric contents Secure airway
79
Physiologic changes associated with pneumoperitoneum Trendelenburg: combined with pneumoperitoneal pressure, the t-burg position increased ____ 150% over baseline
ICP
80
Increased ICP may potentially lead to ____ ____
Brain injury
81
Physiologic changes associated with pneumoperitoneum Trendelenburg: however, if ____ ____ is suspected, the position of choice is t-burg with leaf lateral tilt ( ______ position) to prevent the bubble from traveling to the right ventricular outflow tract and causing an ______
Gas embolism Durant position Airlock
82
Position of choice
Durant position
83
Physiologic changes associated with reverse trendelenburg: (5)
- allows optimum exposure and minimizes the possibility of bowel injury for some procedures - decreased venous return - decreased LVEDV - maintained EF in healthy pts, decreased in others - decreases negative pulm effects of peritoneal insufflation
84
Rate of CO2 absorption is determined by: ____ _____ of the gas, the _____ ______ gradient across the membrane, and ____ ____ across the cavity
Tissue solubility Diffusion pressure gradient Blood flow
85
PaCO2 will rise due to ____ ____ of _____
Significant amounts of absorption
86
Increased absorption with extraperitoneal versus intraperitoneal due to lack of containment of ____ allowing an increased area for ____ ____
CO2 Gas exchange
87
______ can easily occur resulting in increased catecholamines
Hypercarbia
88
Max absorption of ____ occurs at intraabdominal pressure of ____ torr
CO2 10 torr
89
PaCO2 levels level off ___ ____ after insufflation occurs
40 mins
90
Extraperitoneal can occur _____ as with lap inguinal hernia repair or _____ due to misplaced trocar
Purposefully Accidentally
91
EtCO2 accurately predicts changes in PaCO2 in _____, _____ _____ patients
Healthy, mechanically ventilated
92
EtCO2 _____ increase comparably with increase in PaCO2 in patients with _____ disease
DOES NOT Cardiopulmonary
93
Prevent effects of Hypercarbia by controlled ____ _____ ventilation with increased _____ to decrease PaCO2 to normocarbia (target Vt __-__ ml/kg - increase ___ to maintain 35-45 mmHg PaCO2)
Positive pressure MV 5-8 ml/kg RR
94
Prevent effects of Hypercarbia by minimizing SNS stimulation and ____ which would add to the increased risk of ____ ____ (premedicate with anxiolytic and use 100% O2)
Hypoxia Cardiac arrhythmias
95
_____ is the most widely accepted technique to lap procedures
GA
96
GA requires controlled ______, ___ ____ to minimize pulm compromise, and it alters ____ response thus spontaneous ventilation under GA results in _____
Ventilation Muscle relaxant Ventilatory Hypercarbia
97
____ NMB during lap surgeries improves the surgical space conditions when compared with _____ NMB, furthermore it also reduces postop pain scores
Deep Moderate
98
With regional anesthesia, studies showed no _____ due to adequate alveolar ventilation under _____ anesthesia
Hypercarbia Epidural
99
When regional was combined with general, there was better ___ ____ but not better ____ function
Pain relief Pulm function
100
LA can be performed but is ____ ____
Not optimal
101
With the use of LA, there may be inability to ____ ____ if Hypercarbia develops, delay in treating complications, risk of injury if patient moves unexpectedly, need to ____, ____, __/___.
Control respiration Explain Anxiety N/V
102
N2O is ____
Controversial
103
N2O is more soluble than _____ and can move into __-____ spaces faster than _____ can move out causing distention
Nitrogen Air-filled Nitrogen
104
Increase of ____ ____ size after 4 hours of breathing N2O
Intestinal lumen However, surgeons were unable to say if the patient was receiving N2O after 70-80 mins of a lap chole procedure
105
N2O causes _____ of air embolism
Expansion
106
N2O causes increased ____ but no difference in ____
Vomiting Nausea
107
We must provide adequate ____ ____ to avoid risks of injury to organs or vessels or umbilical hernia
Muscle relaxation
108
Evacuate any air from _____ to minimize ____ _____ and avoid risk of injury during Veress needle insertion
Stomach Gastric distention
109
Stop _____ during insertion of Veress needle to avoid pushing abdominal contents up toward the needle
Ventilation
110
Explain increased risk of postop ____ and ____ with laparoscopy (48%) and use ____ _____ measures
Nausea and vomiting Multimodal prophylactic measures
111
Laparoscopy is less painful than ____ ____ (___ ___) but still painful
Open procedure (lap chole)
112
Analgesia options: (5)
- pre-incisional infiltration - intraperitoneal instillation of local (?) - TAP block - NSAIDs (talk to surgeon) - opioids
113
Opioids induce ____ of the ____ of _____ (lap chole) and can be antagonized with ____, ____, or _____. Also causes increased __/__
Spasm of the sphincter of Oddi Glucagon (1st choice), NTG, or narcan N/V
114
Deferred pain to shoulders r/t _____ of the _____, and occurrence is likely on ___ ___ post op
Irritation of the diaphragm First day
115
Assist the surgeon to expel as much CO2 as possible by giving ____ ____ to the patient as trocar is open at the ____ of the case
Deep breaths End
116
_____ and _____ can occur during the creation of the pneumoperitoneum secondary to reflex _____ stimulation from stretching and distention of peritoneum.
Bradycardia and asystole Vagal
117
______ arrhythmias can occur due to hypercarbia
Ventricular
118
____ can occur due to compression of the IVC, hemorrhage, and gas embolism
PEA
119
CO2 enters the circulation via ____ ____ ___
Open venous access (needle in a vessel, portal circulation)
120
Because of solubility of ____, small amounts may be _____ without _______ (___% TEE)
CO2 Reabsorbed Consequence 69% TEE
121
With large amounts of CO2, embolus may form ___ ____ in the ____ atrium or ventricle to impair venous return and ____ ventricular outflow
Gas lock Right Right
122
It may reach the pulm circ, cause _____ and ____ failure
PHTN RH
123
In lap chole patients, (ASA I-III) had relatively small ____ ____ detected with _____
CO2 emboli TEE
124
Presenting signs of CO2 embolus: (7)
- hypotension - jugular venous distention - tachycardia - mill wheel murmur - rapid, but short-lived increase in EtCO2 followed by a decrease - hypoxemia - cyanosis
125
For CO2 embolism, ____ insufflation and ____ peritoneum
Stop Release
126
Place pt in _____ position with ____ side down to prevent bubble from entering right ventricular outflow tract (____)
T-burg Left Durant
127
_____ to reduce CO2 levels
Hyperventilate
128
Insert ____ to aspirate bubble from right atrium
CVL
129
Raise ____ by giving ___ volume
CVP IV
130
Complications of laparoscopic surgery: tracking of insufflation CO2 around the ____ and ______ hiatuses of the diaphragm into the ______ and rupture of the ____ ____
Aortic and esophageal hiatuses Mediastinum Pleural space more likely during lengthy procedures and during procedures on the lower esophagus
131
Complications of laparoscopic surgery: Rupture of ____ ____ or ____
Lung bulla or bleb
132
Complications of laparoscopic surgery: Unexplained increased airway ____, _____, severe CV compromise with _____, SC _____
Pressure Hypoxemia Hypotension Emphysema
133
Complications of laparoscopic surgery: Treatment - deflation of the ____ and ___ ___ decompression if hemodynamically unstable. Small pneumothoraces may be treated conservatively and allowed to _____
Abdomen and chest tube decompression Reabsorb
134
Complications of laparoscopic surgery: Pulmonary dysfunction - less than ____ ____ but still compromised. ______ dysfunction may last up to 24 hours
Open procedure Diaphragmatic Alveoli recruitment maneuver important
135
Complications of laparoscopic surgery: ___ ___ ____ - compression stockings and early ambulation
Deep vein thrombosis
136
Complications of laparoscopic surgery: ___ ___ ____ - compression stockings and early ambulation
Deep vein thrombosis
137
Patient positioning with: - prostatectomy: _____ ____ - pelvis: _____ with ____ ____ - hold patient’s positioning
Steep trendelenburg Lithotomy with steep trendelenburg
138
____ of procedure is important and so are pressure points. Caution to avoid ____ ____, _____ neuropathy, and lat fem cutaneous nerve injury
Length Brachial plexus Ulnar
139
____ abrasions v. Ischemic ____ _____
Corneal Optic neuropathy
140
Fluid limit - __-__ ____ of crystalloid, consider colloid use
1-2 Liters
141
Fluid restrictions to minimize ____, UOP to interfere with reanastomosis must be balanced with too ____ to cause oliguria, one suggestion is ____ ml until vesicourethral reanastomosis, then infuse ____-____ ml by end of surgery
Edema Dry 800 700-1200
142
Robotic assisted laparoscopic radical prostatectomy patients have mean age of ____ years old
60
143
Robotic prostatectomy pts have increased incidence of ____ and ____ abnormalities r/t prostatic hypertrophy
CAD Renal
144
Robotic prostatectomy pts need _____ assessment and assessed for _____ ____
Airway Peripheral neuropathies
145
COPD pts may be difficult to _____. _____ control is better than ____ control BUT PIPs greater than __-__ cm H2O can result in barotrauma
Ventilate Pressure Volume 50-60 cm H2O
146
Thoracoscopy - indicated for _____ procedures as well as operative lung ____
Diagnostic Biopsies
147
Thoracoscopy - patient positioned in the ____ ____ position
Lateral decubitis
148
Thoracoscopy- ____, _____, or ____ anesthesia
Local, general, or regional (Intercostal nerve block alone or with spinal or epidural block)
149
Thoracoscopy - ___-___ ventilation using a ___-____ ETT placed in ____ mainstem
One-lung Double-lumen Left
150
Thoracoscopy - video assisted thoracic surgery (VATS) indicated for ___ ____ and ____ ___
Lung nodules and pleural effusion
151
Thoracoscopy - ____ resection
Wedge
152
Thoracoscopy - lung resections formally requiring ____ ____ ____
Open thoracotomy incision
153
Thoracoscopy - ___ small incisions
3
154
Thoracoscopy - ____-____ ventilation is required
One-lung
155
Gasless Lap - uses no ______
Pneumoperitoneum
156
Gasless Lap - technique using _____ ____ using a _____ retractor - lifts abdominal wall __-___ cm with on lay __-__ mmHg IAP
Abdominal lift Mechanical retractor 10-15 cm 1-4 mmHg
157
Gasless Lap - avoid effects of CO2 insufflation and ____ ______ pressures
High intraabdominal
158
Gasless Lap - minimal changes in ______, ____ functions, and ______ responses
Cardiopulmonary Renal Neuroendocrine
159
Gasless Lap - may benefit ___ ____ and ____ patients
ASA III-IV
160
Hysteroscopy - endoscopic exam of the _____ and _____ _____
Endocervix and endometrial cavity
161
Hysteroscopy - cavity of uterus must be ____ with either ___ or ____ distending media
Distended CO2 Liquid
162
Hysteroscopy - indications (5)
- diagnostics for infertility - abnormal uterine bleeding - localization of IUD - resection of the septae - adhesions or lesions
163
Hysteroscopy - anesthesia - ______ block, ____, or _____ (not preferred). Limit ____ _____ intake
Paracervical block Regional general (not preferred) IV fluid
164
Resectoscope (TURP syndrome) distending media (3)
- CO2 - Hyskon (32% dextran) - Glycine 1.5%
165
CO2 - diagnostic only due to ____ _____ with ____ causing embolism [Resectoscope (TURP Syndrome)]
Open vessels with resection
166
Hyskon (32% dextran) - anaphylaxis, ____ overload, pulm _____, _____ failure [Resectoscope (TURP Syndrome)]
Fluid Edema Renal
167
Glycine 1.5% - ____ overload, hypo____, hypo_____, hyper_____, hyper____ [Resectoscope (TURP Syndrome)]
Fluid overload Hyponatremia Hypoosmolality Hyperammonaemia Hyperglycinaemia
168
Resectoscope (TURP syndrome) - close attention must be paid to ____ ____ versus ____ _____; ____ level prep and intraperitoneal if increased _____ _____ and post op
Volume in Volume out Na Volume intake
169
Resectoscope (TURP Syndrome) - ____ is metabolized into ammonia but the liver resulting in ammonia toxicity - _____, _____ changes, _____.
Glycine Seizures Mental Lethargy
170
Resectoscope (TURP syndrome) - if large volumes are absorbed, ______ ______ can occur with hypervolemia, hyponatremia, and decreased osmolarity causing _____ _____ aka TURP syndrome.
Osmolar hyponatremia Cerebral edema
171
Resectoscope (TURP syndrome) - can result in ____ (sys and dias), ______, CNS changes, __/__, HA, _____ and _____ - may lead to cardiac arrest
HTN Bradycardia N/V Agitation Lethargy
172
TURP syndrome early signs and symptoms: (4)
- restlessness leading to confusion - blurring of vision - HA - N/V
173
TURP syndrome CV signs: unexplainable ____ followed by decreased _____, refractory ______, nodal/junctional rhythm, ____ changes, ____ waves, widening of _____.
HTN BP Bradycardia ST changes U waves Widening of the QRS
174
TURP syndrome fluid absorption: average rate of absorption is ____ml/min (>___L/hr)
20 ml/min > 1 L/hr
175
TURP syndrome circ overload: absorption, ___ ___ increases, ____ and ____ pressure increases, affects contractility and potentiates ______, dilutes ____ and decreases _____ pressure, fluid moves into _____ - (pulm and cerebral edema)
Blood volume increases Sys/dias pressure increases Failure Proteins Oncotic Interstitial
176
Prevention of TURP - use _____ anesthesia
Regional
177
Prevention of TURP - Use ____ v. _____
Saline v. Glycine
178
Prevention of TURP - minimize _____ ______ time
Surgical resection
179
Prevention of TURP - >1 hr of surgical resection time is associated with _____ _____
Increased risk
180
Prevention of TURP - TURP has occurred within ___ ____ of surgery time
15 mins
181
Prevention of TURP - Different surgical techniques such as ____ _____
Laser vaporization
182
Prevention of TURP - ______!!!!! Increased risk with _____ ______
COMMUNICATION Capsular perforation
183
Prevention of TURP - If suspected, complete procedure ____, draw labs such as (4)
Quickly CBC, lytes, Na, and osmolality
184
Prevention of TURP - Administer ___ ____ and _____
Normal saline and furosemide
185
Prevention of TURP - Glycine deficits of ___ mL lead to decreases in ____ of ____ mEq/L
500 mL Na of 2.5 mEq/L
186
Prevention of TURP - If under GA, mental status changes are ______
Not assessable
187
Prevention of TURP - _____ anesthesia is recommended
Regional
188
Prevention of TURP - Correction of Na is important as Na < ____ has increased risk of mortality. However, hypertonic saline should be given only to correct at __-___ ____. Correcting too rapidly can lead to ____ ____ ______ with paresis, mutism, pseudobulbar palsy and other neurological disorders
120 mEq/L 1-2 mEq/L/hr Central pontine myelinolysis
189
Endoscopy factors: (7)
- NPO - bowel prep - sedation “analgesia adequate in the absence of substantial pain or grimacing” - airway management and patient safety - patient satisfaction - positioning - PONV and recovery
190
Endoscopy - _____ compared with ____/____ in a community setting
Propofol Midazolam/fentanyl