Exam II Anesthesia For Thoracic Surgery Flashcards
Leading cause of cancer deaths in the US
Bronchogenic cancer
Better prognosis with _____ than with ____ or _____
Resection
Chemo
Radiation
COPD patients ___ ____ ____ to get lung cancer
4x more likely
Bronchogenic cancer has ____ ____ d/t aging population and co-morbidities
Increasing morbidity
___ needing resections are disqualified d/t ____ ____ ____
40%
Poor pulmonary function
____-_____ ____ ____ has led to a decrease in postop complications such as dysrhythmias, MI, PE, PNA, and emphysema
Video-assisted thoracic surgery (VATS)
Bronchogenic cancer risk factors: (3)
- smoking
- air pollution
- industrial chemicals
Smokers need evaluation for ____ or ___ ___ ___
HTN
Ischemic heart disease
____ history needs stress testing
COPD
Continue ____ ____ throughout perioperative course
Beta blockers
Consider ___ ___ ____ if coronary bypass needed
6-week delay
Radiographic airway evaluation for ______ _____
Mediastinal masses
Endocrine evaluation - rule out _____ _____ caused by some lung tumors
Paraneoplastic syndromes
Neuroendocrine tumors can cause ____ _____
Carcinoid syndrome
_____ occurs in up to 25% of lung cancer pts
Hypercalcemia
Hypercalcemia symptoms: (6)
- polyuria
- polydipsia
- confusion
- vomiting
- abdominal cramping
- bradycardia
COPD symptoms: (4)
- paradoxical breathing
- tympanic chest percussion
- rhonchi
- wheezing
cor pulmonale symptoms: (4)
- jugular vein distention
- peripheral edema
- split S2
- rales
Need a CXR in pre-op to test for:
[Pre-op Testing]
- airway eval
- CHF
- PTX
- tracheal shift
- PA enlargement (sign of increased PVR)
-Eval for airway infringement
EKG: tall R in V1 =
RVH
EKG: biphasic P in V1 =
R atrial hypertrophy
EKG: look for (3)
- ST depression
- BBBs
- T inversion
EKG: Pathologie Q waves + LVH =
Increased risk of ischemia/infarction
Best initial tool for pulmonary HTN but higher level studies may need to follow
Echo
Labs to check for COPD patients: (5)
- room air ABG to check for CO2 retention (>45 = poor function)
- SpO2 < 90% = increased risk of complications
- albumin < 3.6 g/dL (common) = 2.5x higher risk
- BUN > 22 mg/dL = increased risk
- renal fxn labs (esp with chemo)
- lytes (esp Na, K, Ca)
PFTs: significant improvement = ____ increase in ____ after bronchodilators
12% increase in FEV1
PFTs: ___ ____ test is a good predictor. ___-____ testing is best
No single
Multi-modal
PFTs: general cutoffs for increased risk: ____, _____, and _____ < 40%
PPO (predicted post op)
FEV1 (forced expiratory volume/1 second)
DLCO (diffusion in the lung of carbon monoxide)
PFTs: general cutoffs for increased risk: ____ ____ < 15(10) mL/kg/min
VO2 max (ability to climb 5 flights of stairs = > 20, inability to climb 1 flight = < 10)
Non CV surgeries:
____ of smokers have complications
____ of past smokers have complications
____ non-smokers have complications
22%
13%
5%
Lung cancer patients: ___ are smokers
87%
With lung cancer, smokers have a ____ ____
1.5% mortality
With lung cancer, non-smokers have ____ ____
0.4% mortality
Pack-year index = ____/____x____
Packs / day x years
____ = increased complications over moderate smokers
> 20
Smoking cessation ____ ____ ____ = NO difference in outcomes or possibly worse d/t increased _____ _____
< 4 weeks
Mucus production
_____ drops and _____ _____ improves in 1-2 weeks but NO difference in outcomes
Carboxyhemoglobin
Mucociliary clearance
Some improvement in ___ ____ but more at ___ ____
4 weeks
8 weeks
Smoking is difficult to successfully intervene d/t ___ ____ of treating ____ ____
Urgent nature
Lung cancer
_____ monitoring
Standard
___ ___ best for dysrhythmias
Lead II
____ is best for ischemia
V5
Consistent findings: ____ ____ significantly most effective
Lead combo (lead II and V5)
Arterial line should be placed in the _____ arm
Dependent
____ optional
Foley
PAC evidence: (3)
- NO improvement in outcomes
- frequent inaccurate measurements
- caution in vessels that could be clamped or ligated
____ for complex cases with large fluid shifts. Caution with ____. Insert _____ on _____ side
CVP
EJs (easily kinked in lateral position)
Subclavian
Operative
Insert subclavian CVP on operative side why?
Don’t want a double pneumo
Trachea:
__-__ cm long
Begins at ____
Bifurcates at ____
11-12 cm long
C6 (cricoid cartilage)
T5 (sternomanubrial joint)
R mainstem bronchus:
Wider
Angles ____ from trachea at ____
Divides into ____ lobar branches
Orifice of right upper lobe __ to ___ cm from carina
Away from trachea at 20 degrees
3 (upper, middle, lower)
1-2 cm from carina
L mainstem bronchus:
Narrower
Angles ____ from trachea at ____
Divides into ___ lobar branches
Orifice of left upper lobe ___ cm from carina
Away from trachea at 45 degrees
2 (upper, lower)
5 cm from carina
Perfusion (Q): increases from ___ to ____ with awake, spontaneous ventilation
Apex to base
Ventilation (V): increases from ____ to ____. More ____ pressure in the apices keeps alveoli _____.
Apex to base
Negative
Distended
Alveoli in bases less _____, more _____, so most tidal breathing (air movement) distributed to the _____.
Distended
Compliant
Bases
V/Q not being perfectly correlated net result is…
V/Q matching well enough for efficient gas exchange
More _____ pressure in the apices keeps alveoli _____
Negative
Distended
Alveoli in bases less _____, more _____, so most tidal breathing is distributed to ____
Less distended
More compliant
Distributed to bases
Lateral Awake: _____ displacement of diaphragm on DEPENDENT side
Cephalad
Lateral Awake: So, during inspiration, diaphragm can contract further leading to better ventilation of _____ lung
Dependent
Lateral Awake: Perfusion _____ in _____ lung (gravity)
Higher
Dependent
Lateral Awake: Net result of V/Q and gas exchange
Net result of V/Q - no significant change
Gas exchange is efficient
Lateral, anesthetized, spont vent, chest closed: induction leads to decreased ____ ____ ____
Functional residual capacity (FRC)
Lateral, anesthetized, spont vent, chest closed: Cephalad diaphragm displacement leads to ____ _____
Decreased FRC
Lateral, anesthetized, spont vent, chest closed: ______ lung is more compliant leading to _____ ventilation
NonDependent
Increased
Lateral, anesthetized, spont vent, chest closed: _____ lung is more _____ (gravity)
Dependent
Perfused
Lateral, anesthetized, spont vent, chest closed: V/Q net result
Mismatched
Lateral, paralyzed, mech vent, chest closed: with mech vent, diaphragm no longer helps maintain ____ leading to further decrease in ventilation in _____ lung and increased vent in ______ lung and ____ V/Q mismatch
FRC
Dependent
NonDependent
More
Lateral, paralyzed, mech vent, chest closed: PEEP ____ ____ leading to ____ V/Q mismatch
Improves FRC
Less
Lateral, anesthetized, chest open: huge reduction in resistance in ______ lung leading to increased ventilation in _____ lung and further decreased vent in ______ lung
NonDependent
NonDependent
Dependent
Lateral, anesthetized, chest open: Mediastinum shifts _____ d/t loss of _____ _____ pressure
Downward
Negative intrathoracic pressure
Lateral, anesthetized, chest open: Vessels can be _____ leading to decreased ____ ____
Compressed
Cardiac output
Lateral, anesthetized, chest open: With spontaneous vent (theoretically) leads to _____, _____ exchange. Air from the open-chest _____ lung moves into the ______ lung
Paradoxical, inefficient
NonDependent
Dependent
Paradoxical Respiration: during inspiration, air from the open-chest ______ lung moves into the ______ lung
NonDependent
Dependent
Paradoxical Respiration: During expiration, air moves from ____ lung to the open-chest _____ lung
Dependent
NonDependent
Paradoxical Respiration: _____ ventilation helps, but ______ lung is much better ventilated. ______ lung is much better perfused. (Gravity)
Mechanical
NonDependent
Dependent
Paradoxical Respiration: Net result - major ____ _____ in dependent lung
Physiologic shunt
reminder that this is theoretical and should NOT occur
With mechanical (positive pressure) ventilation, Paradoxical Respiration and Mediastinal shift are _____. But _____ compliance of the NonDependent lung in open chest leads to ____ _____ _____
Reduced
High
HUGE V/Q mismatch
What situation has the worst V/Q mismatch? And why do you care?
Lateral, anesthetized, paralyzed, open-chest patient
We care bc we have to deal with this exact situation for the duration of the surgery
Lateral, open-chest, one-lung ventilation (OLV): ____ resistance, _____ compliance of NonDependent lung which leads to ____ ventilation
Low
High
High
Lateral, open-chest, one-lung ventilation (OLV): _____ in dependent lung leads to ____ perfusion
Gravity
High
Lateral, open-chest, one-lung ventilation (OLV): When vent stops in NonDependent lung, all _____ is diverted to _____ lung
Ventilation
Dependent
Lateral, open-chest, one-lung ventilation (OLV): Perfusion to ______ lung now creates a ______
NonDependent
Shunt
Lateral, open-chest, one-lung ventilation (OLV): BUT HPV in ______ lung diverts perfusion to ______ lung and decreases the ______ effect
NonDependent
Dependent
Shunt
Lateral, open-chest, one-lung ventilation (OLV): Net result - ____ V/Q mismatch (clinical picture ____ when _____ lung is clamped)
Less
Improves
NonDependent