Exam II Flashcards
GnRH OT
Peptides <20AA
Gonadal ridge➡️
Pronephros: ⛔️fn
Mesonephros: male wolffian
Paramesonephros: female mullerian
Metanephros: kidneys
PRL
Placental lactogen
Protein: mem-bound R
FSH LH
eCG
Inhibin
Glycoproteins
T
E2
P4
Cortisol
Steroids: nuc-R➡️❇️RNA syn
PG
Fatty Acids: mem-bound R
Ideal R
High aff & spec
Low capacity
GnRH
Decapeptide
HT➡️❇️pitu (gonadotroph cells): FSH+LH rel
LH surge➡️✳️OV
FSH
Glycoprotein
a + ß subunits
A.pitu➡️❇️spermatogen/folliculogen
LH
Glycoprotein
a + ß subunits
A.pitu➡️❇️Leydig cells: T syn/✳️OV & maintain CL
hCG ~LH act
Steroidgenesis
27C(chol)
➡️21C(P4)➡️19C(T)➡️18C(E2)
P4
21C
Prod: CL + placenta + adr gl ➡️
⛔️GnRH secr
Fn: preps uterus-⬆️gl & histotroph
⬇️smM contractions
Rx: regumate, CIDR
T
19C
Leydig cell:❇️ 2nd sex ch & behavior
E2
1-3 [OH] groups
Ov Follicles + placenta + adr gl➡️
❇️FB Loop
❇️endometrium, smM contract,
mam gl dev, 2nd sex ch & behavior
PG
ARA
Endometrium(PGF2a)➡️✳️leutolysis
❇️smM contract & OV & birthing
PGE2➡️✳️ovary/ut/embyo➡️OV + CL
Rx: colic side effects