Exam 6 - Diabetes Flashcards

1
Q

What is the most reliable measure for assessing diabetes control over the preceding 3-month period? What should it be?

A

Hemoglobin A1C lab test
should be under 7 (6.5)

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2
Q

What are short term complications of diabetes?

A

hypoglycemia, hyperglycemia, ketoacidosis

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3
Q

What are long term complications of diabetes?

A

Macro:
cardiovascular disease (and ATHEROSCLEROSIS)
hypertension
stroke

Micro: damage to small vessels and capillaries
nephropathy, retinopathy, neuropathy - sensory/motor, gastroparesis (stomach doesn’t empty so the gastric cells continue to secrete enzymes and you throw up bile), amputations, erectile dysfunction

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4
Q

What are the three signs of hyperglycemia?

A

polyuria, polyphagia, polydipsea

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5
Q

Which of all the insulins is NOT clear? What will the nurse do to prepare the med prior to drawing the med into the syringe?

A

NPH – it is cloudy
roll it, don’t need to shake it

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6
Q

What is tight glycemic control? What is the benefit? What are some considerations?

A

trying to avoid the fluctuations
they might have a glucose monitor and insulin pump on them
-if they do a good job there is decreased risk of cardiovascular disease and renal complications
considerations:

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7
Q

Which of the following medications has the most rapid onset? which can you use in an IV as an infusion?
A) Humulin
B) Novolin
C) Lispro

A

Lispro is the most rapid
Regular insulin is the only one you can use in an IV as an infusion

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8
Q

Lispro (Humalog) info.

A

short acting, short duration
SUbQ administration
may be mixed in the same syringe with NPH
may be used in combination with intermediate and long-acting insulins
Onset: 10-30min // Peak: 30-2.5 hrs // Duration: 3-6hrs

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9
Q

What teaching will the nurse provide to the patient who will begin self administration of Lispro? How long once

A

-rotate the site
-keep the sites clean (wash your hands)
-store in the fridge to last longer (once opened, can store 3 months in the fridge, and 1 month outside of the fridge)
-avoid direct sunlight and high temperature areas
-prefilled syringes should be kept in the fridge and used within 1-2 weeks

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10
Q

what is the right order of NPH and regular insulin when administering together?

A

clear before cloudy

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11
Q

what are the signs of hypoglycemi?

A

shaking, decreased LOC, confusion, diaphoretic, tachycardi

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12
Q

glargine
- what is the best time for the patient to take this?

A

make sure to administer the same time everyday (b/c it is 24hr acting)

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13
Q

which antibiotic works by decreasing glucose production by the liver and decreases glucose uptake by muscle and adipose tissue?

A

Biguanide (metformin)
-does not promote insulin release
**fill out this slide more

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14
Q

Which medication will stimulate the release of insulin?

A

Sulfonylureas (glyburide)
-watch out for hypoglycemia

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15
Q

How can the nurse remember the drugs are sulfonylureas?

A

Glipizide, Glypburide
Glimepiride

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16
Q

Metformin (Biguanide) ADRS – What is the admin route?

A

-decreases appetite
-nausea and diarrhea
-Lactic Acidosis (rare but serious), esp in pts with renal insufficiency
– will be adminstered PO

17
Q

Glipizide Sulfonylurea ADRs

A

Hypoglycemia, mostly with kidney and liver dysfunction
and weight gain

18
Q

What medication might mask the signs of hypoglycemia? what are signs of hypoglycemia

A

beta blockers, signs are “Weak, shaky, hangry”

19
Q

What are the drugs that might cause hypoglycemia?
Biguanides
Sulfonylureas
Meglitinides
Thiazolinediones
Alpha-glucosidase
DPP4 Inhibitors
Sodium-Glucose Co-Transporter 2 Inhibitors
Glucagon-like Peptide-1 Receptor Agonist
Incretin Mimetic
Amylin Mimetic

A

Sulfonylureas, Meglitinides, DPP4 Inhibitors, Incretin Mimetic, Amylin Mimetic

20
Q

What are other medications that are used in patient with Diabetes ?

A

ACE inhibitors and ARB
Statins