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Pharmacology > Drugs For exam 4 > Flashcards

Drugs For exam 4 Flashcards

1
Q

Furosemide

A

Loop diuretic
Watch out for hypokalemia

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2
Q

Spironalactone

A

Diuretic
Aldosterone Antagonist
Reduces Na and water retention

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3
Q

Sacubritil/valsartan

A

ARNI
-increases Natriuretic peptides
-blocks angiotensin 2 receptors
ADRS: hyperkalemia, hypotension, decreased GFR

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4
Q

Lisinopril

A

ACE Inhibitor

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5
Q

Losartan

A

ARB
-no cough side effect

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6
Q

Dapagliflozin

A

Type 2 diabetes drug now used in Hf
Induces weight loss thru glucose secretion in urine
side effects:
More GU infections
Increased UOP

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7
Q

Dobutamine

A

Activates beta 1 receptors
Increases contractility
Catecholamine
Short term rescue of severe HF
Adverse effects: hypertension, tachycardia

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8
Q

Carvedilol, Bisoprolol, Sustained release Metoprolol

A

Only 3 beta blockers effective for HF

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9
Q

Digoxin

A

Toxicity more likely to occur with hypokalemia

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10
Q

Milrinone

A

Increases contractility and leads to vasodilation
Inhibits PDE3
Positive inotrope

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11
Q

Nifedipine and Amoldipine

A

Calcium channel blockers Does not affect the heart
Promotes arterial dilation and reduced afterload

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12
Q

Diltiazam and Verapamil

A

Calcium channel blockers that also block channels in the heart
And relaxes vasospasm
Used for variant anginA

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13
Q

Adenosine

A

Drug of choice for Paroxysmal Supraventricular Tachycardia
Immediate onset
Very short half life

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14
Q

Amiodarone

A

-Potassium channel blocker
-approved for life threatening VENTRICULAR DYSRHYTHMIA
- used for both atrial and
Ventricular dysrythmias
-lots of organ toxicitie
T-thyroid
2-P peripheral and photosensitivity
2L -Lung and Liver
2C- cardia and cornwa

NO GRAPEFRUIT JUICE

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15
Q

Lidocane

A

Sodium channel blocker
-short term therapy of ventricular dysrhythmias
ADRS: CNS drowsiness & cardiac dysrythmias

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16
Q

Procainamide

A

Sodium channel blocker
Supraventricular and ventricular dysrythmias
Lots of ADRs: CNS, lupus-like syndrome, blood dycrasias

17
Q

Epinephrine

A

Alpha 1 , beta 1 & beta 2

Adverse effects are hypertensive crisis
Dysrythmias
Hyperglycemia

18
Q

Norepineohrine

A

Alpha 1, alpha 2, beta 1
Does not promote hyperglycemia

19
Q

Dopamine

A

Dopamine and beta 1
And alpha 1 at high doses
Increases cardiac output
Increases perfusion
Dilate renal vessels

20
Q

-statin

A

Inhibit cholesterol production
Lower LDL, raise HDL, reduce triglycerides
** take in the evening
** need to take for the rest of their lives

21
Q

Atropine

A

Anticholinergic
Increases cardiac output, increases heart rate
Use for brady cardia

22
Q

Tadalafil

A

/ erectile dysfunction agent
Vasodilator
PDE-5 inhibitor

23
Q

Renalisine

A

Angina

24
Q

Ivabradine

A

Lowers heart rate
By blocking channels responsible for SA node

Pharmacology (18 decks)

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