Drugs For exam 4 Flashcards
Furosemide
Loop diuretic
Watch out for hypokalemia
Spironalactone
Diuretic
Aldosterone Antagonist
Reduces Na and water retention
Sacubritil/valsartan
ARNI
-increases Natriuretic peptides
-blocks angiotensin 2 receptors
ADRS: hyperkalemia, hypotension, decreased GFR
Lisinopril
ACE Inhibitor
Losartan
ARB
-no cough side effect
Dapagliflozin
Type 2 diabetes drug now used in Hf
Induces weight loss thru glucose secretion in urine
side effects:
More GU infections
Increased UOP
Dobutamine
Activates beta 1 receptors
Increases contractility
Catecholamine
Short term rescue of severe HF
Adverse effects: hypertension, tachycardia
Carvedilol, Bisoprolol, Sustained release Metoprolol
Only 3 beta blockers effective for HF
Digoxin
Toxicity more likely to occur with hypokalemia
Milrinone
Increases contractility and leads to vasodilation
Inhibits PDE3
Positive inotrope
Nifedipine and Amoldipine
Calcium channel blockers Does not affect the heart
Promotes arterial dilation and reduced afterload
Diltiazam and Verapamil
Calcium channel blockers that also block channels in the heart
And relaxes vasospasm
Used for variant anginA
Adenosine
Drug of choice for Paroxysmal Supraventricular Tachycardia
Immediate onset
Very short half life
Amiodarone
-Potassium channel blocker
-approved for life threatening VENTRICULAR DYSRHYTHMIA
- used for both atrial and
Ventricular dysrythmias
-lots of organ toxicitie
T-thyroid
2-P peripheral and photosensitivity
2L -Lung and Liver
2C- cardia and cornwa
NO GRAPEFRUIT JUICE
Lidocane
Sodium channel blocker
-short term therapy of ventricular dysrhythmias
ADRS: CNS drowsiness & cardiac dysrythmias
Procainamide
Sodium channel blocker
Supraventricular and ventricular dysrythmias
Lots of ADRs: CNS, lupus-like syndrome, blood dycrasias
Epinephrine
Alpha 1 , beta 1 & beta 2
Adverse effects are hypertensive crisis
Dysrythmias
Hyperglycemia
Norepineohrine
Alpha 1, alpha 2, beta 1
Does not promote hyperglycemia
Dopamine
Dopamine and beta 1
And alpha 1 at high doses
Increases cardiac output
Increases perfusion
Dilate renal vessels
-statin
Inhibit cholesterol production
Lower LDL, raise HDL, reduce triglycerides
** take in the evening
** need to take for the rest of their lives
Atropine
Anticholinergic
Increases cardiac output, increases heart rate
Use for brady cardia
Tadalafil
/ erectile dysfunction agent
Vasodilator
PDE-5 inhibitor
Renalisine
Angina
Ivabradine
Lowers heart rate
By blocking channels responsible for SA node
