Exam 5: Renal Function and ABG Flashcards

1
Q

What is the average glomerular filtration rate in a healthy adult?

A

120 mL/min when surface area = 1.73

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2
Q

What does the term “glomerular filtration rate” mean?

A

The volume of plasma that is completely cleared of a solute in a unit of time, expressed in mL/min.

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3
Q

What is the cause of pre-renal failure?

A

Decreased renal blood flow

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4
Q

What is the cause renal failure?

A

Direct renal tissue damage

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5
Q

What is the cause of post-renal failure?

A

Obstruction of urine flow

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6
Q

What hormones are the kidneys responsible for producing?

A

Renin, prostaglandins, and erythropoeitin.

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7
Q

What does renin do?

A

produced by kidney and maintains sodium and potassium levels to help control blood pressure

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8
Q

What does erythropoeitin do?

A

increases rate of RBC production

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9
Q

What do prostaglandins do?

A

a group of lipids that control processes involving inflammation, blood flow and the formation of blood clots

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10
Q

What are the four blood buffer systems?

A

Phosphate, protein, hemoglobin, and bicarbonate

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11
Q

What are some causes to perform blood gas testing?

A

Lung and breathing disorders
Acid-base imbalances
Kidney problems
To monitor/evaluate patient conditions

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12
Q

Which response to changes in the body’s acid/base status is faster- lungs or kidneys? Which one is more potent?

A

The lung’s response to acid-base changes is much faster, but the kidney is more potent although it is slower response.

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13
Q

What are the four categories of acid-base imbalance that can occur in the body?

A

Metabolic alkalosis
Metabolic acidosis
Respiratory acidosis
Respiratory alkalosis

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14
Q

What are some causes of metabolic alkalosis?

A

Excess administration of sodium bicarb (exogenous increase of alkali)

Diuretic therapy (endogenous increase in alkali)

Increased loss of hydrogen ions through vomiting

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15
Q

What are some causes of metabolic acidosis?

A

Accumulation of fixed acid or loss of extracellular buffers (increase in hydrogen ions or decrease in bicarb)

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16
Q

What are some causes of respiratory acidosis?

A

Lung disease (accumulation of CO2)
Airway obstruction
Certain drugs that slow respiratory rate
Decreased cardiac output (CHF)

17
Q

What are some causes of respiratory alkalosis?

A

Excessive elimination of CO2 by the lungs caused by hyperventilation (hypoxemia)

18
Q

What is the normal ratio of bicarbonate to carbonic acid in the body? What happens if this ratio changes?

A

The normal ratio is 20 bicarb for every 1 carbonic acid molecule. If this ratio is off, the pH of the blood will increase/decrease.

19
Q

How is oxygen delivered to the body’s tissues?

A

Through hemoglobin with the help of 2,3 diphosphoglycerate to regulate oxygen affinity of hemoglobin

20
Q

What factors affect the hemoglobin-oxygen dissociation curve?

A

pH, temperature, pCO2, and 2,3-DPG.

Decreased affinity = increased temp, increased 2,3-DPG, decreased pH, and increased pCO2.

Increased affinity = increased pH, decreased temp, decreased 2,3-DPG, and decreased pCO2.