Exam 4 Green Packet Flashcards
What are the contraindications for anticoagulants, antiplatelets and thrombolytics? (6)
Excessive blood loss
Hemorrhage
Closed head injury
Hemorrhagic stroke
Prior to surgery
Pregnancy/lactation*
*Genetic conditions only
What is the purpose of antiplatelet drugs?
To prevent thrombosis by inhibiting platelet aggregations or clumping
May decrease CVA/MI
Clopidogrel (Plavix) is what type of medication?
Antiplatelet (~grel)
What is the purpose of anticoagulants?
Reduce clotting by interfering with clotting factors. Fibrinogen to fibrin.
Inhibit further clot formation
What are some uses of Heparin? (7)
DVT - thrombosis clot
PE - blood clot
MI - heart attach
heart valve devices
Thrombotic stroke
Orthopedic surgeries
Post-op
What are the side effects/adverse reactions to heparin? (3)
Itching
Burning
Bleeding
What is the antidote of heparing?
Protamine Sulfate IV - not a sulfonamide
When is heparin given SQ?
Post-op
Knee/bone manipulation surgeries
When is heparin given IV?
Acute MI
Acute stroke (CVA)
What are you monitoring when your patient is on heparin?
PTT
What is the therapeutic range for PTT?
60-90
What is Enoxaparin (Lovenox)?
Low molecular weight heparin
~parin
What is the antidote for LMWH Enoxaparin (Lovenox)?
Protamine sulfate
What drug is typically sent home with patients in a pre-filled syringe given once per day?
Enoxaparin (Lovenox)
Leave air bubble in!
Based on body weight
What are you monitoring when giving warfarin?
PT
INR
What is the therapeutic range of INR for those on coumadin?
2.0-3.0
What is the antidote for warfarin?
Vitamin K
What are some side effects/adverse reactions of warfarin? (3)
Anorexia
N/V/D
Bleeding
How long can it take for warfarin to become therapeutic?
3-7 days
What teaching will you provide a patient on coumadin?
Keep intake of vitamin K consistent.
Soft toothbrush
Electric razor
How quickly must a thrombolytic be given to be effective on current clots and prevent side effects?
3-4 hours
How long does it take to see results of statins?
2-3 weeks
What are the three new anticoagulant drugs that have less diet changes?
Dabigatran (Pradaxa)
Xa inhibitors - rivaroxaban (Xarelto) - Apixaban (Eliquis)
What is the first test a patient should get if a thrombolytic is to be given?
CT
Determine if clots are caused by aneurism
What is the one drug that can dissolve current clots?
Thrombolytics (~plase, ~kinase)
What are some adverse reactions of thrombolytics? (3)
Anaphylaxis
Hemorrhage
Arrythmias
What are three nonpharmacological ways to lower cholesterol?
Diet - <=30% fats, <=300 mg cholesterol
Exercise
No smoking
What is the use of antilipemics?
Lower abnormal blood lipid levels (cholesterol)
What are side effects of taking niacin for high cholesterol? (5)
GI upset
Flush/cramping
Hyperglycemia
Hyperuricemia
Abnormal liver function
What medication is a powder that must be taken with fluids and mixed with water or juice?
Questran - bile acid sequestrants
What major adverse reaction are you looking out for when on statins?
Rhabdomyolysis - muscle tenderness or weakness. Attacks the kidneys, hyperhydrate, dialysis.
What are the 3 most important teachings for a patient on statins?
Do not abruptly stop! Sever hypercholestemia leading to heart attack.
Monitor liver enzymes
Annual eye exam (cataract formation)
What is the most prescribed antilipidemic?
Vastatins or Statins
~statin
What are side effects of statins? (4)
GI upset
Headache
Muscle cramps
Tiredness
What is the biggest intervention for patients on peripheral vasodilators?
Safety! Low blood pressure, fall risk.
What is the blood force that stretches the LV?
Preload
What is the resistance to LV ejection of blood?
Afterload