Exam 4 Flashcards

1
Q

Estrogen warning and adverse reactions

A

Category x
Black box warning:
-Endometrial & Breast CA
-Cardiovascular Disorders
-Dementia
-blood clots
Adverse:
Weight gain
Cholasma (melasma) dark skin

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2
Q

Conjugated estrogen

A

aka Premarin
-topical & oral
For atrophic vaginitis and epastaxis 👃🏽🩸

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3
Q

Ethinyl estradiol

A

aka Estrace
Topical and oral
Commonly in BC 💊

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4
Q

Estradiol transdermal

A

aka Duavee, FemPatch
Patch
Lower abd by ovaries
Vasomotor for menopause

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5
Q

Progestin warnings and adverse reactions

A

Category X -spontaneous abortion
Black box warning: 🖤
Endometrial & Brease CA
Cardiovascular disorders
Dementia
Adverse effects:
Amenorrhea, spotting
Pyrexia (+body temp)
Depression

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6
Q

Medroxyprogesterone

A

aka Amen, Provera, Depo-Provera
Oral, IM,
Contraception
Loss of bone density +2yrs, especially for younger than 25yrs

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7
Q

Megestrol

A

aka Megace
Oral
+appetite for CA & AIDS

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8
Q

Contraception Black box warning

A

Cardiovascular Disease
Breast & Endometrial CA
Dementia
Cigarette smoking +🩸clots

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9
Q

When you miss a BC pill you..

A

Take asap
1 missed pill- back up BC for 1wk
2 missed pills- use back up 1 month

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10
Q

BC Forms

A

IM- q 3/m
TD patch- 3wks on 1wk off
NuvaRing- 3wks on 1wk off

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11
Q

What supplements should you take for Osteoperosis?

A

Calcium & Vitamin D

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12
Q

Bisphosphonates
(Osteoperosis)

A

Inhibit osteoclasts

alendronate (Fosamax) 1/2 life 10yrs
ibandronate (Boniva) PO & IV- back & joint pain
-drink with water
-take in morning
-upright for 30 min due to jaw osteonecrosis

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13
Q

Monoclonal Antibody (Osteoporosis)

A

denosumab (Prolia)
mab= + risk for infection/CA
Blocks osteoclasts
Can lead to Jaw ostoonecrosis

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14
Q

Parathyroid Hormone teriparatide (Osteoperosis)

A

aka Forteo
Can cause significant Tachycardia

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15
Q

Selective Estrogen Receptor Module
SERM (Osteoperosis)

A

raloxifene (Evista)
Gives hot flashes

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16
Q

Finasteride

A

aka Propecia
Proscar - BPH reduction
Category X- abortion
-decreased libido
-loss of erection
-gynecomastia

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17
Q

minoxidil

A

aka Rogaine
For women and men for alopecia

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18
Q

causes of erectile dysfunction

A

Stress
Hyperlipidemia (- 🩸 flow)
Obesity (low T)
DM
Depression
Sleep Apnea
Drug use

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19
Q

sildenafil

A

aka Viagra
Take 1hr prior
Interaction with Nitroglicerine
Adverse Reactions:
-Priapism (long boner)
-HA
-Flushing

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20
Q

Testosterone & Anabolic steroids

A

Black box warning:
DVT, PE, MI, peliosos Edema
Transdermal Patch
Androderm
Androgel
Axiron- underarm spray
IM

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21
Q

Isotonic Crystalloids

A

0.9% NaCl (NS)
Lactate Ringers
Use for dehydration

22
Q

Hypotonic Crystalloids

A

0.45% NaCl (Half NS)
used for dehydration with Nl BP

23
Q

Hypertoniv Crystalloid

A

D5NS
HIGH RISK
+BP & possible stroke
Mannitol (diuretic) for cerebral edema- doesn’t +BP

24
Q

Normal Potassium level

A

3.5 - 5 mEq/L

25
Q

Hypokalemia

A

Occurs with loop diuretics
Causes dysrhythmia

26
Q

Potassium replacement

A

Needs renal assessment first
(needs to pee before)

PO- eat with food
IV- cardiac monitor

27
Q

Hyperkalemia

A

❤️ reacts quick to + potassium
Dysrhythmia

28
Q

For potassium toxicity you give

A

Sodium bicarbonate and calcium gluconate

29
Q

Normal sodium level

A

135-145 meq

30
Q

Level of hyponatremia

A

Below 120 meq
Can cause seizures

31
Q

Sodium replacement

A

PO & IV
Can cause N/V so take with food

32
Q

Hypernatremia symptoms

A

Decreased urine output
Water retention
Increased thirst

33
Q

GFR level

A

90-140 mL

34
Q

Carbonic Anhydrase Inhibitors

A

For high altitude sickness
Related to sulfonamide (Bactrum)
Don’t use if renal failure
Can cause hypokalemia

acetazolamide (Diamox)
methazolamide

35
Q

Loop Diuretics

A

Don’t use if hypokalemia
Ok to use for renal failure
furosemide (Lasix)
bumetanide (Bumex)
torsemide (Demadex)

36
Q

mannitol

A

aka Osmitrol

Osmotic Diuretic (reduces intracranial pressure)
Shifts fluids
IV only
Crystallizes in cold

37
Q

Potassium sparing diuretics

A

Used in Peds with ❤️ failure
(So potassium doesn’t decrease)
Adverse reactions:
Boobs, no period, kidney stones

spironolactone (Aldactone)
amiloride (Midamor)
triamerene (Dyrenium)

38
Q

Thiazides (HCTZ)

A

1st line of defense for HTN
“Water pill”
-Family to sulfonamide
-Renal function decreases
-As dose +, hypokalemia & hyperglycemia

39
Q

Kidney function test

A

BUN 8-25mg (Buns a 10)
GFR >90mL/ min
Serum creatinine 0.6-1.5mg (1 Blood)
SG 1.001 - 1.030

40
Q

nitroglycerin
(Notrates/Nitrite Meds)

A

aka (Nitrostat)

Sublingual, patch (constant), IV
Lay down
Absorption of 2-3 min-take a 2nd tab w/no relief
No relief of 5 min take 3rd
Burning sensation is nl

41
Q

isosorbide dinitrate
(Nitrates)

A

aka Isordil
powerful explosive
Rapid sublingual
Hard drug to control

42
Q

isosorbide mononitrate

A

aka Imdur

Sustained release messier to control
Constant therapeutic results

43
Q

Beta blockers for Angina

A

atenolol (Tenormin)
metoprolol (Lopressor)
nadolol (Cogard)
propranolol (Inderal)

Decreases ♥️ rate and BP

44
Q

Calcium Chanel blockers for Angina

A

Prevents muscle contraction & causes arterial dilation

diltiazem (Cardizem)
amlodipine (Norvasc)
verapamil (Calan)

45
Q

What do Andre regicide Blocking drugs do?

A

Blocks epinephrine
(Alpha blockers & Beta blockers)

46
Q

tamsulosin
(Alpha Blocker)

A

aka Flomax
Relaxes vascular in ureters and prostate
Treatment of BPH & kidney stones

47
Q

Other Adrenergic blocking drugs

A

prazosin (pressure & prostate)
alfuzosin (BPH)
silodosin (BPH)

48
Q

propranolol (Beta Blocker)

A

Decreases ♥️ rate
Don’t give to asthmatic or DM (bronchoconstriction)
Treatment of HTN, Angina, Migraine, Anxiety

49
Q

metoprolol
(Beta blocker)

A

aka Lopressor
Decreases ♥️ rate
Drug of choice for asthma or DM

Treatment of HTN & MI

50
Q

atenolol (Beta blocker)

A

Decreases ♥️ rate

Treatment of HTN, Angina, prevents future MI

51
Q

esmolol (Beta Blocker)

A

aka Brevibloc
Decreases ♥️ rate
Treatment of superventricular tachycardia