Exam 4 Flashcards
Estrogen warning and adverse reactions
Category x
Black box warning:
-Endometrial & Breast CA
-Cardiovascular Disorders
-Dementia
-blood clots
Adverse:
Weight gain
Cholasma (melasma) dark skin
Conjugated estrogen
aka Premarin
-topical & oral
For atrophic vaginitis and epastaxis 👃🏽🩸
Ethinyl estradiol
aka Estrace
Topical and oral
Commonly in BC 💊
Estradiol transdermal
aka Duavee, FemPatch
Patch
Lower abd by ovaries
Vasomotor for menopause
Progestin warnings and adverse reactions
Category X -spontaneous abortion
Black box warning: 🖤
Endometrial & Brease CA
Cardiovascular disorders
Dementia
Adverse effects:
Amenorrhea, spotting
Pyrexia (+body temp)
Depression
Medroxyprogesterone
aka Amen, Provera, Depo-Provera
Oral, IM,
Contraception
Loss of bone density +2yrs, especially for younger than 25yrs
Megestrol
aka Megace
Oral
+appetite for CA & AIDS
Contraception Black box warning
Cardiovascular Disease
Breast & Endometrial CA
Dementia
Cigarette smoking +🩸clots
When you miss a BC pill you..
Take asap
1 missed pill- back up BC for 1wk
2 missed pills- use back up 1 month
BC Forms
IM- q 3/m
TD patch- 3wks on 1wk off
NuvaRing- 3wks on 1wk off
What supplements should you take for Osteoperosis?
Calcium & Vitamin D
Bisphosphonates
(Osteoperosis)
Inhibit osteoclasts
alendronate (Fosamax) 1/2 life 10yrs
ibandronate (Boniva) PO & IV- back & joint pain
-drink with water
-take in morning
-upright for 30 min due to jaw osteonecrosis
Monoclonal Antibody (Osteoporosis)
denosumab (Prolia)
mab= + risk for infection/CA
Blocks osteoclasts
Can lead to Jaw ostoonecrosis
Parathyroid Hormone teriparatide (Osteoperosis)
aka Forteo
Can cause significant Tachycardia
Selective Estrogen Receptor Module
SERM (Osteoperosis)
raloxifene (Evista)
Gives hot flashes
Finasteride
aka Propecia
Proscar - BPH reduction
Category X- abortion
-decreased libido
-loss of erection
-gynecomastia
minoxidil
aka Rogaine
For women and men for alopecia
causes of erectile dysfunction
Stress
Hyperlipidemia (- 🩸 flow)
Obesity (low T)
DM
Depression
Sleep Apnea
Drug use
sildenafil
aka Viagra
Take 1hr prior
Interaction with Nitroglicerine
Adverse Reactions:
-Priapism (long boner)
-HA
-Flushing
Testosterone & Anabolic steroids
Black box warning:
DVT, PE, MI, peliosos Edema
Transdermal Patch
Androderm
Androgel
Axiron- underarm spray
IM