Exam 3 shit Flashcards
Francisella tularensis
Causes Tularemia, transmitted by ticks (usually dermacentor) from wild rabbits, hasheat stable and heat labile toxin at 4 degrees Celsius
Characteristics of Tularemia
Ulcero-glandular most common, ulcero-glandular, glandular, pneumonic, typhoid are others. Treat with aminoglycosides like streptomycin. REPORTABLE. Can be confused with plague
Actinobacillus equuli
Causes Sleepy Foal disease, foals are lethargic because of infection that goes to the CNS and brain. Endotoxin is the virulence factor
Sleepy Foal disease is caused by
Actinobacillus equuli
RB51 vaccine
Live vaccine so it has an abortion risk, used for Brucella abortus (can cause Bang’s disease), vaccine is avirulent because there is no “O” side chain of the LPS, causes cell-mediated immunity
Sterne vaccine
For Bacillus anthracis, the disease caused is anthrax, avirulent because it lacks a capsule due to the loss of plasmid (no pXO2), leads to humoral immunity
Swine dysentery
Caused by Brachyspira hyodysenteriae. Leads to mucus and blood in the feces. Mostly affects the colon. Classic sign is the hemorrhagic necrotic intestinal mucosa. Use Carbadox to treat. Hemolysin is virulence factor
Brachyspira hyodystenteriae
Gram - spiral shaped, causes swine dysentery, affects the colon, causes mucohemorrhagic feces, has hemolysin as a virulence factor
Swine proliferative enteritis
Caused by Lawsonia intracellularis. Ileum is affected. Can see hypoproteinemia diarrhea. Enterocyte proliferation leads to a thickened mucosa with a cerebriform pattern. Use Tiamulin to treat. Lawsonia Surface Antigen A is a virulence factor.
Lawsonia intracellularis
Obligate intracellular pathogen. Gram - curved rod. Has lawsonia surface antigen A as a virulence factor. Causes swine proliferative enteritis.
Actinomyces suis
Causes UTIs in sows that has foul smelling urine. Older sows get it more frequently because they are in stalls that have an increased fecal contamination, decreased water consumption, infrequent urination. Passed venerally, has urease as a virulence factor. Usually in swine. Is a Gram + rod that is anaerobic.
UTI in sows
Caused by Actinomyces suis. Has foul smelling urine and usually found in older sows. Urease is the main virulence factor that raises the pH and allows for survival of the organism
Corynebacterium renale
Mostly in cattle, Gram + curved rod with a club shaped swelling on one or both ends, found in the soil. Has urease as a virulence factor. Causes pyelonephritis or hemorrhagic cystitis.
Pyelonephritis/hemorrhagic cystitis
Caused by Corynebacterium renale, has urease as a virulence factor. Found in the soil.
Helicobacter felis
Commonly found in both dogs and cats. Causes gastritis. Have flagella for motility to the mucous surface, urease to raise the pH to promote bacterial growth, and mucinase to break down the mucus lining of the cell surface. Signs include intermittent vomiting, anorexia, dehydration. Take a gastric biopsy and do a PCR or perform a urease test on the sample.
Gastritis in small animals
Caused most likely by Helicobacter felis. Signs are intermittent vomiting, anorexia, and dehydration. Take a gastric biopsy sample and do a urease test to confirm.
Corynebacterium pseudotuberculosis
Caseous lymphadenitis disease. In sheep or goats. Has phospholipase D as a virulence factor. Also called pigeon fever because of the abscesses in the pectoral region for horses
Pigeon fever
caused by Corynebacterium pseudotuberculosis. Characteristic signs include abscesses on the pectoral region.
Erysipelothrix rhusiopathiae
Causes erysipelas in pigs, erysipeloid in humans. Characteristic diamond skin lesions that are directly correlated to how far the disease has progressed. Virulence factors are the capsule and neuraminidase. Is gram + and produces hydrogen sulfide. Chronic form characterized by polyarthritis and endocarditis.
Erysipelas
Disease in pigs caused by E. rhusiopathiae. It is characterized by diamond skin lesions that directly determine outcome of disease, this is the acute form. Recovery using penicillin. Chronic form is characterized by polyarthritis and endocarditis