exam 3 - renal Flashcards
AKI occurs very quickly, occurs over…
hours-days = failure to maintain waste elimination, fluid/electrolyte balance, acid base balance
renal failure results when
the kidneys cannot remove metabolic waste/perform regular functions
AKI diagnostic definition?
increase in Cr by 0.3 in 48 hrs
or
increase in Cr 1.5x baseline 7 days prior
or
urine volume, <0.5ml/kg/hr for 6hrs
ARF and AKI is usually a ______ issue
secondary issues
risk factors for AKI?
shock, cardiac surgery, hypotension, prolonged mechanical ventilation and sepsis, old age and DM
AKI categories?
pre renal, intra renal and post renal
define pre renal AKI
what is it caused by?
most common, reduced blood flow to kidneys
caused by: hypo-perfusiom, hypovolemia, hypotension, burns and sepsis
define intra renal
what is it caused by?
issue within kidney affecting renal cortex/medulla
caused by: allergic disorders, embolism, thrombosis of renal vessels, nephrotoxic drugs (NSAIDs), gentamicin/vanc
define post renal
what causes it?
urine flow obstruction
caused by calculi, tumors, or urethral obstruction
what does body do during pre/post renal to try to fix issue? what does this lead to?
tries to compensate which improves perfusion but reduces urine output and builds up waste in the blood
what causes AKI? what is AKI? what happens if you dont try to tx underlying conditions?
usually caused by an underlying condition = reduced cardiac output or causes obstruction of kidney
blood flow reduced to kidneys, leading to impaired function
if underlying conditions are not tx = renal failure
what is phase 1 of AKI
initiation: begins w/initial result = oliguria
what is phase 2 of AKI
oliguria (small amount of urine produced), accompanied by increase in serum concentration of substance usually excreted by kidneys
what is phase 3 of AKI?
diuesis: gradual increase in UOA which = glomerular filtration is recovering
what is phase 4 of AKI?
recovery: signs of improvement, may take 3-12 m