Exam 2 Flashcards
Left sided heart failure
S/sx? S
S3 -when in overload
↑ hr, weak pulses, cyanosis, cool extremities
Nocturnal/exertional dyspnea
Orthopnea, ↑ rr
Elevated pulmonary capillary wedge pressure
Pulmonary congestion ( cough, crackles, wheezes, blood tinged sputum)
Restless, dizzy, confusion, AMS
Right side heart failure
What is the other name? Why?
What are the s/sx?
Cor pulmonale, due to being secondary to chronic pulmonary problems
JVD (RV cannot pump more venous blood into lungs)
Loud S2 pulmonic component (lubDUB)
RV heave on palpitation
RUQ pain, Fatigue, ascites, enlarged liver/spleen, polyuria/nocturia
-Weight gain, dependent edema, anorexia, gi distress
Where is heart attack pain located?
Upper chest, substeral, epigastic, neck, jaw, both arms and intrascapular
Heart attack s/sx
Men vs women
Men: n/v, jaw/neck/back pain, chest pressure, sob
Women: n/v, jaw, neck, upper back pain, chest pain but NOT always, pain/pressure in low chest or abdomen, sob, fainting, indigestion, extreme fatigue
What lab values do we look at for MI vs Heart failure?
Troponin, myoglobin, creative kinase, potassium, mag, cholesterol
BUN/Cr/BNP = heart failure
Semi vs non nstemi
Stemi: St elevation, increased troponin = infarction and necrosis
Nonstemi: ST depression, t wave inversion = myocardial ischemia. Troponin ↑ can occur, both happening = myocardial cell death/ necrosis
Stemi pathophysiology
Rupture of fibrous atherosclerotic plaque = plt aggregation / thrombi form at site
Begins w/infarction of subendocardial layer of heart muscles which has greatest 02 demand and ↓ supply
Define
Zone of injury
Zone of ischemia
Zone of injury: Tissue injured not necrotic
Zone of ischemia: Tissue that is o2 deprived
What metabolic process occurs during mi?
K+, calcium, mag = changes in conduction and contraction
Catecholmines (epi/norepinephrine) released in response= ↑ hr, afterload and contraction
-increase 02. Requirements = ventricular rhythms
Ml risk factors?
Smoking, HTN, DM 2, obesity, alcohol, sedentary, stress, cholesterol ↑, metabolic syndrome, hyperlipemia
Race (black), age (65 yr), gender (male), family hx
What is MI?
What occurs in blood flow?
Myocardial infarction
Occlusion of blood flow = ischemia → injury → necrosis
What is Mona?,
What order do we give it in?
Morphine, oxygen, nitro, aspirin
O2 first
Nitro: 3x every 5 min
Morphine: ↓ pain, relax smooth muscle, & catecholmines
-2-4 mg IV push Q5-15 min
Asa - antiplatelet
What is a contraindication of nitro? What is a common side effect?
Viagra / pulmonary hypertension, “afil” drugs= fatal interaction;
Headache and orthostatic Hypotension
What medications do we give for mi?
What is one surgical intervention?
Vast dilator (nitro)
Analgesics ( morphine)
Beta blockers ( carvedilol, metoprolol )
Antiplatelets ( Asa, clopidogrel, varapraxor)
Thrombolytic therapy ( Alteplase)
Anticoags heparin, enoxaprin)
Glycoprotein inhibitors (eptifibatide)
Percutaneous coronary intervention (PCI)
What is the s/sx of cardiogenic shock?
, Cold, clammy skin
↓ pulses
Agitation
Pulmonary congestion
↑ RR, ↓ bp, ↑ hr, ↓ UOA
What is coronary artery disease?
What does it lead to?
What does it include?
Plaque buildsup in artery
Angina: hard for blood to go through artery
Heart attack: plaque cracks and a blood clot blocks artery
Includes: stable angina, ischemia, infarction
Define ischemia and infarction
Ischemia: Insufficient O2 for myocardium
Infarction: necrosis & cell death occurs when severe ischemia is prolonged and ↓ perfusion = irreversible damage
Types of angina?
Stable
Unstable
Variant (prinzmetals)
Describe stable angina
Occurs on exertion, exercise or emotional stress
Relieved by nitroglycerin
Last less than 15 min
Not associated w/n, epigastric pain, dyspnea, anxiety, diaphoresis
Describe unstable angina
Considered pre-infarction. Occurs w/wo exertion (even at rest)
Progressively gets worse
S/sx: diaphoresis, sob,
Describe variant (prinzmetal) angina
. Due to coronary artery spasm, occurs at rest
Describe EKG of pts w/angina
ST changes but no troponin/ ck levels
How does blood flow through heart? What is the acronym that helps?
Try
Performing
Better
Always
(Tricuspid, pulmonary, bicuspid, aortic valve)
What are the 2 subcategories of heart failure
Systolic (impaired contractility)
Diastolic (impaired filling)