Exam 3 - Obesity II Flashcards
What BMI is the cutoff for increased DM risk?
> 22 BMI increases risk for T2DM 25%
Describe the etiology of T2DM in obese individuals
• Excess fat elevates fasting and post-prandial FFA
• Increased FFA
- increases pancreatic b-cell secretion of insulin
- inhibits cellular insulin resistance
- causes peripheral IR
- reduces glycogen storage
- increases hepatic glucose production
**HYPERGLYCEMIA, HYPERINSULINEMIA, IMPAIRED GTT and eventually T2DM
Describe the etiology of why hypertension is an issue for obese individuals
Adipocyte-related factors containing angiotensinogen and metabolies of FFA - both stimulate aldosterone release
List some commodities of obesity
- T2DM
- Hypertension
- Hepatobiliary disorders
- Metabolic syndrome
- IR/pre-diabetes
- Sleep apnea
- Acanthosis nigricans
Describe the etiology of hepatobillary disorders in obese individuals
• Cholesterol gallstones form when cholesterol concentration in bile becomes supersaturated and crystals grow
Name the five factors of Metabolic Syndrome
- Elevated WC**
- Elevated TAGs
- Reduced HDL
- Elevated BP
- Elevated fasting glucose**
**Dominant underlying risk factors
Name the risk factors for sleep apnea
- Obesity - fatty cells infiltrate throat tissue
- Habitual snoring - changes in soft palate
- Family history
- Immune abnormalities - High TNF-a and IL-y
- GERD
Describe possible sleep apnea treatments
• LIFESTYLE CHANGES - sleep on side - nasal strips • WEIGHT LOSS • SUBSTANCE USE - quit smoking - no alcohol w/in 4 hrs of sleep - no sleeping pills and tranquilizers • CPAP
Describe acantrosis nigricans and its cause and treatement
• Velvety, light brown to black markings
- usually on neck, under arms or in groin
•Cause: insulin “spillover” into skin
• Treatment: reduce circulating insulin by weight reduction
What are the general guidelines for medical management of obesity?
- Diet
- Physical activity
- Behavioral therapy
*For some, medications and/or bariatric surgery
Describe the use of equations for estimating and measuring energy requirements of obese individuals
The best method is to do a “usual intake” recall and go from there in terms of cutting calories
•Mifflin-St Jeor can be helpful, bc used some obese people were included
What are the three factors in Nutrition Assessment?
- Anthropocentric measurements
- Client history and biochemical data
- Food/nutrition-related history
What might be included in a Nutrition Diagnosis for obesity?
- Excessive energy intake
- Food and nutrition related knowledge deficit
- Disordered eating pattern
- Undesirable food choices
- Overweight/obesity
- Involuntary weight gain
- Physical activity
Describe appropriate nutrition intervention weight loss goals
Initial goal of 5-10% baseline weight loss within 6 months (through caloric restriction, increased physical activity, or both)
Give some broad caloric deficit guidelines for BMI<35 to achieve energy defecit
500-750 kcal deficit/day to lose 1/2-1lb/week
OR
intake of 1200-1500 kcal/day for women; 1500-1800 for men