Exam 3 - Obesity I Flashcards

1
Q

Describe the term PREVALENCE in relation to obesity

A
  • The total number of existing cases of a disease/condition in a given population at a designated time
  • Eg: amount of people in a room having their period right now
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2
Q

Describe the term ODDS RATIO in relation to obesity

A
  • A way of comparing whether the probability of a certain even is the same for two groups
  • Odds ratio = 1 - implies the event is equally likely in both groups
  • Odds ratio > 1 - implies the event is more likely in the first group
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3
Q

Describe the rise of obesity rates in US

A
  • 1980 - no state had adult obesity rate > 15%
  • 1991 - no state had adult obesity rate > 20%
  • 2010 - no state had adult obesity rate < 20%
  • 2015 - 22 states have rates >30%; 4 states > 45%
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4
Q

Which age group has the most obesity in US?

A

40-59; more women than men

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5
Q

Who is the most likely to have extreme obesity (BMI>40) in US men?

A

Does not differ by age, race, smoking status or education

** Does differ by age and race in women; not by smoking or education
•• More women than men BMI>40

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6
Q

What percent of children are obese according to 2015-2016 NHANES data? How has this changed in recent years?

A

18.5% obese (BMI>95th %ile)

It hasn’t changed; BUT significant increase in extreme obesity (BMI>120%)

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7
Q

Describe body fat percent

A

The amount of adipose tissue in your body as a percentage of total body weight

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8
Q

Describe ESSENTIAL FAT. What is its purpose? Where is it? How much do men and women have?

A

Needed for normal physiologic functioning

  • Stored in small amounts in bone marrow, heart, lung, liver, spleen, etc
  • Men - 3% total body fat is essential
  • Women - 12% (bc includes fat in breasts, pelvis, and thighs that support repro process)
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9
Q

Give the body fat percentages for men and women in the RISKY (HIGH BODY FAT) body fat rating

A

Men: >30%
Women: >40%

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10
Q

Give the body fat percentages for men and women in the EXCESS FAT body fat rating

A

Men: 21-30%
Women: 31-40%

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11
Q

Give the body fat percentages for men and women in the MODERATELY LEAN body fat rating

A

Men: 13-20%
Women: 23-30%

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12
Q

Give the body fat percentages for men and women in the LEAN body fat rating

A

Men: 9-12%
Women: 19-22%

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13
Q

Give the body fat percentages for men and women in the ULTRA LEAN body fat rating

A

Men: 5-8%
Women: 15-18%

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14
Q

Give the body fat percentages for men and women in the RISKY (LOW BODY FAT) body fat rating

A

Men: <5%
Women: <15%

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15
Q

BMI for Underweight category

A

<18.5

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16
Q

BMI for Normal category

17
Q

BMI for OVERWEIGHT category. How does a normal vs large WC affect disease risk in this?

A

Overweight: 25.0-29.9
•Normal (Men <40”; Women<35”): Increased
• Large (Men >40”; Women>35”): High

18
Q

BMI for OBESE I category. How does a normal vs large WC affect disease risk in this?

A

Obese I: 30.0-34.9
• Normal (Men <40”; Women<35”): High
• Large (Men >40”; Women>35”): Very high

19
Q

BMI for OBESE II category. How does a normal vs large WC affect disease risk in this?

A

Obese II: 35.0-39.9
• Normal (Men <40”; Women<35”): Very high
• Large (Men >40”; Women>35”): Very high

20
Q

BMI for EXTREMELY OBESE category. How does a normal vs large WC affect disease risk in this?

A

Extremely obese: >40
• Normal (Men <40”; Women<35”): Extremely high
• Large (Men >40”; Women>35”): Extremely ery high

21
Q

Describe some limitations of BMI

A
  • Very muscular people may fall into “overweight” category
  • People who lost muscle mass (like elderly) may be in “healthy weight” category
  • May not detect edema
  • Assumes adipose tissue is distributed evenly over body (apple vs pear)

*Useful as general guideline, not as diagnostic of person’s health

22
Q

Describe CT imaging in measuring body fat distribution

A

Can be used to identify lean mass and visceral adipose tissue
•Shows cross-sectional slices distinguishing bone, muscle, and adipose tissue and calculate the cross-sectional areas

23
Q

Describe MRI imaging in measuring body fat distribution

A
  • No exposure to radiation
  • More $$, but give cleaner, 3D diagnosis
  • Can discern between visceral and subcutaneous fat
24
Q

Describe DXA imaging in measuring body fat distribution

A

• Does not discriminate well btwn visceral and subcutaneous fat, but can esimate

25
Describe Waist:Hip ratio. What are the cut points and what do they signify?
Increased abdominal WC related to hip girth shown to be predictive of >CHD and T2DM • Men: 0.90-0.95 • Women: 0.80-0.85 • Elevated WHR represent elevated risk for disease development
26
Give the pros and cons of using waist circumference. Give the cut points.
PRO - only one measurement (less error than WHR) CON • May avoid population specific trends in hip size, unrelated to visceral fat amount • More dependent on total adiposity than WHR * Central obesity: >35" women; >40" men * No J-shaped curve like in BMI
27
Which measurement identifies CVD risk best? T2DM? HTN? CVD?
* WC and WHR - CVD risks better than BMI | * WHR - T2DM, HTN, and CVD better than WC
28
Describe metabolically obese normal-weight (MONW)
Have normal BMI but suffer from complications assoc with obesity (often identified if someone gains weight but is still in "normal" BMI)
29
Describe metabolically healthy obese (MHO)
Have BMI>30 but no complications associated with obesity | • characterized by high generation of new adipocytes and low hypertrophy
30
What is a key factor in differing between MONW and MHO?
The amount of VAT •Most MONW with low BMI have significant excess VAT; most MHO with high BMI have less VAT
31
Describe Hypertrglyceridemic waist. What is the risks associated with it and cut-off points?
Simple clinical phenotype predictive of excess VAT • Men with low WC and Tg were at less risk of being VAT obese, while 80% of those with hypertriglyceridemic waist had high VAT • Cut-off: WC of 90cm in men; 85cm women; 1.5mM/L for TG in men
32
List some obesogenic factors
*  Healthy food availability * Screen time * Food choices * Doing other things while eating * Portion sizes * Less exercise