Exam 3 Lower Motor System Flashcards
General organization of the motor system—e.g., lower motor neurons, upper motor
neurons,
Lower motor neurons: innervate skeletal muscles of head and body
Local circuit neurons: major source of synaptic input to lower motor neurons
Upper Motor Neurons: Cell bodies in the cortex, projections to local circuit neurons and lower motor neurons
Basal Ganglia: Initiated movement and prevent unwanted movement
Cerebellum: Detects and corrects motor errors
What is meant by the “final common pathway”?
Motor neurons in the spinal cord are the final common pathway for all motor action
Alpha Motor Neurons
large motor neurons in the ventral horn; innervate striate muscle fibers
Motor Unit
Combination of muscle fiber & ⍺motor neuron
Combination of muscle fiber & ⍺motor neuron
Motor Neuron Pool
⍺motor neurons that innervate a particular muscle form a column in the spinal cord
End-Plate potential (EPP)
depolarization of the postsynaptic muscle fiber
Miniature EPP’s (MEPP)
occur spontaneously
Describe the somatotopic organization of lower motor neuron pools in the spinal cord:
Medial motor neurons project to more proximal muscles & Lateral motor neurons project to more distal muscles.
Describe the anatomy and function of medial local circuit neurons:
Medial: extend over several spinal cord segments, terminate bilaterally, synchronous bilateral coordination of muscles (posture, breathing, locomotion)
Describe the anatomy and function of lateral local circuit neurons
Lateral: extend over a few spinal cord segments, terminate ipsilaterally, fine control of distal extremities (independent movement of fingers)
What neurotransmitter is released at the neuromuscular junction?
Acetylcholine (Ach) released into the synaptic cleft at the neuromuscular junction
What are the 3 types of motor units and their properties? How are they recruited during
a movement?
Slow (S) motor units: Small, innervate weaker muscle fibers, sustained motor activity (posture)
Fast fatigable (FF) motor units: Large, innervate stronger fibers, brief exertions of large force (jumping).
Fast fatigue-resistant (FR) motor units: intermediate.
Recruited from weakest to strongest•Deactivation follows reversed order
What is the function and the components of muscle spindles?
Consist of intrafusal muscle fibers:
Are surrounded by parallel extrafusal fibers(force producing)
Detects stretch of the muscle
Intrafusal fibers controlled by gamma motor neurons
Group Ia afferent axon
Group Ia afferent axon: Rapidly adapting responses, velocity & direction of movement
Group II afferent axons:
Group II afferent axons: Sustained responses to constant muscle lengths, static position of limbs