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Oral Path 2 > Exam 3 longer > Flashcards

Exam 3 longer Flashcards

1
Q

Uncommon neoplasm that probably arise from PDL fibroblasts

A

Central Ossifying Fibroma

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2
Q

Central Ossifying Fibroma…

  • Most common in what area?
  • Most common in which people?
A
  • Lower premolar/molar region

- adult female

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3
Q

Central Ossifying Fibroma..

  • Radiographic Appearance?
  • Affect on teeth?
  • Tx?
A
  • Well circumscribed radiolucency with central opacity
  • root diveregence
  • Enucleation (separates from bone easily in one piece)
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4
Q

Benign osseous tumor that primarily affects paranasal sinuses (and other craniofacial bones)

A

Osteoma

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5
Q

Gardner Syndrome…

  • 1: ____-____ live births
  • One of the ___ syndromes
  • __gene, chromosome ___
A
  • 8000-16000
  • FAP (familial adenomatous polyposis)
  • APC, 5
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6
Q

What is characterized by osteomas of facial bones, epidermoid cysts, and desmoid tumors

A

Gardner Syndrome

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7
Q

Most significant aspect of Gardners Syndrome is the development of:
-__% of patients develop adenocarcinoma of the colon by 30 years of age

A

Precancerous polyps of the colon

-50

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8
Q

Central Giant Cell Granuloma…

  • Most pts are under what age?
  • Sex?
  • tx
  • prog
A
  • 30
  • female 2:1
  • curettage
  • good
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9
Q

What is most common in ANTERIOR MANDIBLE and CROSSES midline

A

Central Giant Cell Granuloma

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10
Q

Hyperplastic response to bone in patients with poorly controlled secondary hyperparathyroidism related to end-stage renal disease:

A

Renal Osteodystrophy

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11
Q

Osteosarcoma…

  • Shows production of ____ by ____ cells
  • ~____ new cases in US annually
  • Peak age: _____, but that’s normally long bones. osteosarcoma of the jaws is usually around __ years
A

-Osteoid by tumor cells
-1000
-teens
35

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12
Q

Which bone malignancy causes PAIN and a symmetrically widened PDL

A

Osteosarcoma

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13
Q

Most common primary bone malignancy:

-What is the most common form of cancer to involve bone?

A

Osteosarcoma

-Metastatic Disease

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14
Q

Osteosarcoma tx:

  • 5 yr survival:
  • Death is more often due to _______ than _____
A

Radical surgery, together with chemo in some cases

  • 60-70%
  • Uncontrolled local disease than metastasis
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15
Q

Which is twice as common as the other (osteo/chondrosarcoma)

A

OSTEOsarcome is twice as common

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16
Q

Chondrosarcoma group of people:

A

Adult MALES

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17
Q

What causes PAIN in femur/pelvis/ribs and rarely in head/neck (unless it’s LOW grade)

A

Chondrosarcoma

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18
Q

Chondrosarcoma tx:

  • 5yr survival:
  • Death is usually due to:
A

Radical surgery

  • 87%
  • Direct extension of tumor, involving vital structures
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19
Q

How can metastatic deposits from malignancies below the neck affect the jaws?

A

Through Batson’s paravertebral plexus of veins which lack valves

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20
Q

Socket in POSTERIOR MANDIBLE (tooth 30) is NOT healing, they might have:

A

Metastatic Disease

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21
Q

__% of jaw metastases represent initial manifestation of the malignant process of Metastatic Disease

A

22

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22
Q

Metastatic Disease…

  • tx:
  • prog
A
  • Palliation, usually with radiation therapy, anti-resorptves
  • VERY POOR (most die within 1 year)
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23
Q

Most common cyst of the jaws

A

Periapical Cyst

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24
Q

Periapical cyst develops due to inflammatory stimulation of:

-Inflammation through lateral canals may lead to:

A

epithelial rests of Malassez

-lateral radicular cyst

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25
Q

Most common DEVELOPMENTAL odontogenic cyst

A

Dentigerous Cyst

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26
Q

When fluid accumulates between crown and REE (reduced enamel epithelium) of an UNERUPTED tooth, it causes:

A

Dentigerous Cyst

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27
Q

When lucent space around crown of unerupted crown is greater than 3-4mm, it’s considered a:

A

Dentigerous Cyst

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28
Q

Most common site for DENTIGEROUS CYST:

-Most common age

A

Mandibular 3rd molar, followed by max canines

-2nd-3rd decade (3rd molars erupting)

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29
Q

Dentigerous cyst that forms in soft tissue

A

Eruption Cyst

30
Q

Rare lesion thought to be derived from degenerating tooth bud epithelium

A

Primoridal Cyst

31
Q

Which cyst develops in place of a tooth, before any mineralized material is deposited

A

Primordial Cyst

32
Q

Usually detected as a unilocular radiolucency in the area of a missing 3rd molar (that was NOT surgically removed…naturally missing)

A

Primordial Cyst

33
Q

Locally aggressive cyst associated with nevoid basal cell carcinoma syndrome is:
-This specific association is suspected in pts under __ yrs old

A

Odontogenic Keratocyst

-15

34
Q

Odontogenic Keratocyst peak age:

  • More common in mandible or maxilla?
  • At what age is anterior maxilla more favored?
A

3rd decade

  • Mandible twice as common
  • Over 60
35
Q

Odontogenic Keratocyst..

  • Present as __locular radio___
  • Tx depends on:
  • Prognosis:
A
  • UNIlocular radioLUCENCY
  • Size
  • guarded (3-62% recurrence)
36
Q

Complex mix of malformations and neoplams exhibiting over 100 different features related to skin, CNS, and skeleton:

A

Nevoid Basal Cell Carcinoma Syndroma

37
Q

What deals with PTCH gene, chromosome 9

A

Nevoid Basal Cell Carcinoma Syndrome

38
Q

__% of mutations are new from Nevoid Basal Cell Carcinoma Sydnrome

A

40%

39
Q

Nevoid Basal Cell Carcinoma Syndrome…

  • Craniofacial features:
  • Affect on skin
  • Radiographic findings
  • Which cysts develop in jaws
A
  • Enlarged cranial circumference, heavy brow ridges
  • 1-2mm shallow pits on palms and soles
  • Lamellar calcification of falx cerebri
  • Odontogenic Keratocysts
40
Q

Presents as 1-2mm yellow-white papules on maxillary ridge of newborn

A

Gingival Cyst of newborn

41
Q

Similar appearing lesions to gingival cyst of newborn..

  • Epstein pearls:
  • Bohn’s Nodules
A
  • occur along MEDIAN palatal raphe and arise from EPITHELIUM entrapped along the line of fusion
  • scattered over the HARD palate, often near the soft palate junction; believed to be derived from the MINOR SALIVARY GLANDS
42
Q

Gingival Cyst of Adult…

  • Related to ______ cyst
  • Arises from:
A
  • lateral periodontal cyst

- dental lamina rests in the gingival connective tissue (rests of Serres)

43
Q

Gingival Cyst of Adult…

  • Area
  • __ on Palpation
  • Predilection?
  • Tx
A
  • Attached gingiva of Canine/premolar
  • tense
  • None
  • Conservative excision
44
Q

What mimics mucocele (blue) but on ATTACHED gingiva

A

Gingival Cyst of Adult

45
Q

Lateral Periodontal Cyst..

  • Are adjacent teeth vital?
  • Area
  • Tx:
A
  • yes
  • mandibular premolar, maxillary lateral incisor
  • Curettage
46
Q

Calcifying Odontogenic Cyst…

  • Aka _____ cyst
  • Maxilla/mandible predilection?
  • Mean age
A
  • Gorlin
  • Nope
  • 33 yrs old
47
Q

Calcifying Odontogenic Cyst…

  • Scattered radiopacities in __% of cases
  • __% of COC’s are associated with impacted tooth, __% with odontoma
  • Resorption of adjacent roots happens in __% of cases
A
  • 50%
  • impacted 30%, odontoma 20%
  • resorption 80%
48
Q

Most common odontogenic neoplasm

A

Ameloblastoma

49
Q

Ameloblastoma..

  • Sex predilection?
  • Age range
A
  • No sex pred

- Very wide 3rd-7th

50
Q

Ameloblastoma…

  • __% occur in mandible (posterior)
  • __% are associated with impacted tooth
A
  • 80%

- 20%

51
Q

Ameloblastoma…

  • Growth rate?
  • Does it perforate bone?
  • Symptoms?
A
  • Slow
  • no, it expands
  • none except swelling
52
Q

Desmoplastic Variant of Ameloblastoma radiographic finding:

A

POORLY demarcated radiolucency with numerous radiopaque flecks

53
Q

Ameloblastoma…

  • Small lesion tx:
  • Large lesion tx:
  • prognosis:
  • Does maxilla or mandible require more aggressive surgical removal (due to anatomical location)
A
  • Small: aggressive curettage or small en bloc resection
  • Large: large n bloc resection or marginal segmental resection with reconstruction
  • Guarded (high recurrence)
  • Maxilla
54
Q

Peripheral Ameloblastoma presents as:

-Prognosis

A

asymptomatic gingival mass in middle-aged adult, usually mandible
-GOOD (this is an innocuous lesion that can easily be cured by local excision, low recurrence)

55
Q

Calcidying Epithelial Odontogenic Tumor (CEOT)..

  • aka
  • mean age
  • Sex predilection
  • area
A
  • Pindborg Tumor
  • 40
  • none
  • posterior mandible
56
Q

Calcidying Epithelial Odontogenic Tumor (CEOT)..

  • __% associated w impacted tooth
  • Radiographically
  • tx
  • __% recurrence rate
A
  • 50%
  • well-circumscribed radiolucency. Can have radiopaque flecks
  • Conservative excision with peripheral ostectomy
  • 15%
57
Q

Adenomatoid Odontogenic Tumor (AOT)…

  • Mean age:
  • Sex predilection?
  • Maxilla/mandible predilection?
  • Tx:
  • Prog
A
  • 18yrs
  • female 2:1
  • maxilla 2:1
  • Enucleation
  • Excellent
58
Q

Adenomatoid Odontogenic Tumor (AOT)..

  • 75% occur in anterior/posterior
  • __% are associated with impacted tooth
A
  • Anterior

- 75%

59
Q

Adenomatoid Odontogenic Tumor (AOT)..

  • Symptoms?
  • Radiographically
  • Affect on adjacent teeth?
A
  • Asymptomatic
  • Well-circumscribed radiolucency w radiopaque flecks
  • Separation of roots/teeth
60
Q

How can you tell the difference of an Adenomatoid Odontogenic Tumor (AOT) from dentigerous cyst

A

When AOT is associated with impacted tooth, the lesion often extends apically beyond the CEJ

61
Q

Ameloblastic Fibroma…

  • Usually in younger/older
  • 70% of cases in what area
  • tx:
  • Prog
  • Malignant transformation common?
A
  • Younger
  • Posterior mandible
  • aggressive curettage
  • good
  • NO, NOT common
62
Q

Odontogenic tumor with features of ameloblastic fibroma as well as odontoma

A

Ameloblastic Fibro-Odontoma

63
Q

Ameloblastic Fibro-Odontoma..

-mean age

A

-10

64
Q

Ameloblastic Fibro-Odontoma..

  • Radiographically it has varying amounts of calcified material having the density of:
  • often associated with:
  • tx:
  • prog
A
  • tooth structure
  • impacted tooth
  • Conservative curettage
  • excellent
65
Q

Odontoma…

  • What are the 2 different forms?
  • Mean age
  • Usually associated with:
A
  • compound or complex
  • 14
  • unerupted tooth
66
Q

Difference of compound and complex Odontomas?

-Where are each usually seen

A
  • Compound: COLLECTION of small malformed teeth often overlying an impacted tooth (ANTERIOR MAXILLA)
  • Complex: calcified MASS that has same density of tooth structure also overlying impacted tooth (POSTERIOR MAXILLA OR MANDIBLE)
67
Q

Odontogenic Myxoma ONLY affects which part of body:

A

Jaw bones

68
Q

Odontogenic Myxoma…

  • Average age:
  • Symptoms:
A
  • 25

- Asymptomatic expansion of the bone

69
Q

Odontogenic Myxoma…

  • Radiographically may have “____” appearance
  • Tx depends on
  • Recurrence rate:
A
  • “soap-bubble”
  • size (small=curettage…large=en bloc or segmental resection)
  • 25%
70
Q

Cementoblastoma…

  • Area
  • Age
A
  • Mandibular molar region

- Under 25

71
Q

Cementoblastoma…

  • Rate of growth
  • Tx
  • Prog
A
  • slow (can produce expansion or pain)
  • Surgical extraction of involved tooth
  • Excellent
72
Q

What is a well-circumscribed radiOPAQUE mass with a fine radiolucent border. Fused to the resorbed root of the mandibular first molar

A

Cementoblastoma

Oral Path 2 (7 decks)

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