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Oral Path 2 > Exam 3 > Flashcards

Exam 3 Flashcards

1
Q

Uncommon neoplasm that probably arises from PDL fibroblasts

A

Central Ossifying Fibroma

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2
Q

Central Ossifying Fibroma….

  • Most common in what area?
  • Most common in which people?
  • Radiographic appearance:
  • Pain?
  • What can it do to teeth?
  • Tx:
A
  • Lower premolar/molar region
  • Adult female
  • Well-circumscribed radiolucency with central opacity
  • No pain, asymptomatic swelling
  • Cause root divergence
  • Enuclueation (usually separates from bone easily in one piece)
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3
Q

Benign osseous tumor that primarily affects paranasal sinuses (and other craniofacial bones)?
-Painful?

A

Osteoma

-No

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4
Q

Gardner Syndrome…

  • Autosomal ______.
  • 1:___-___ live births
  • It is one of the ____________ syndromes
  • ___ gene, chromosome __
  • Characterized by:
A
  • Dominant
  • 8,000-16,000
  • FAP (Familial Adenomatous Polyposis)
  • APC, 5
  • multiple osteomas of the facial bones, epidermoid cysts, and desmoid tumors
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5
Q

Most significant aspect of Gardners Syndrome is the development of:
-__% of patients develop adenocarcinoma of the colon by 30 years of age

A

Precancerous polyps of the colon

-50

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6
Q

Central Giant Cell Granuloma…

  • 60% of pts are what age range
  • What group of people
  • Common area
  • Does it cross midline?
  • Tx
  • Prognosis
A
  • under 30
  • females (2:1)
  • anterior mandible
  • yes, crosses midline
  • Aggressive curettage
  • good
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7
Q

Hyperparathyroidism…

  • Causes inappropriate secretion of:
  • Primary is due to:
  • Secondary is due to:
  • Radiographically:
  • “______” tumors
A
  • parathormone
  • parathryoid hyperplasia, parathyroid adenoma, parathyroid carcinoma
  • renal failure (poor calcium retention and altered vitamin D metabolism)
  • Loss of lamina dura and “ground glass”
  • Brown
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8
Q

Hyperplastic response to bone in patients with poorly controlled secondary hyperparathyroidism related to end-stage renal disease:

A

Renal Osteodystrophy

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9
Q

Osteosarcoma…

  • Shows production of ____ by ____ cells
  • ~____ new cases in US annually
  • Peak age: _____, but that’s normally long bones. osteosarcoma of the jaws is usually around __ years
  • Pain?
  • Affect on PDL?
A

-Osteoid by tumor cells
-1000
-teens
35
-Yes pain
-Symmetrically widened PDL

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10
Q

Most common primary bone malignancy:

-What is the most common form of cancer to involve bone?

A

Osteosarcoma

-Metastatic Disease

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11
Q

Osteosarcoma tx:

  • 5 yr survival:
  • Death is more often due to _______ than _____
A

Radical surgery, together with chemo in some cases

  • 60-70%
  • Uncontrolled local disease than metastasis
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12
Q

Which is twice as common as the other (osteo/chondrosarcoma)

A

OSTEOsarcome is twice as common

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13
Q

Chondrosarcoma…

  • Group of people:
  • Area:
  • Common in head/neck?
  • Pain?
  • Are jaw lesions usually higher or lower grade?
A
  • Adult MALES
  • Femur, pelvis, ribs
  • NO (only 0.1%)
  • Yes
  • Low grade (I or II)
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14
Q

Chondrosarcoma tx:

  • 5yr survival:
  • Death is usually due to:
A

Radical surgery

  • 87%
  • Direct extension of tumor, involving vital structures
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15
Q

How can metastatic deposits from malignancies below the neck affect the jaws?

A

Through Batson’s paravertebral plexus of veins which lack valves

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16
Q

Metastatic Disease…

  • Area:
  • Affect on tooth socket?
  • __% of jaw metastases represent initial manifestation of the malignant process
  • Tx:
  • Prognosis
A
  • Posterior mandible
  • Doesn’t let it heal
  • 22%
  • Palliation, usually with radiation therapy, anti-resorptives
  • VERY POOR…most die within 1 year
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17
Q

Most common cyst of the jaws

A

Periapical cyst

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18
Q

Periapical cyst develops due to inflammatory stimulation of:

-Inflammation through lateral canals may lead to:

A

epithelial rests of Malassez

-lateral radicular cyst

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19
Q

Most common DEVELOPMENTAL odontogenic cyst:

A

Dentigerous Cyst

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20
Q

In a Dentigereous Cyst, fluid accumulates between:

  • It’s associated with the crown of an _____ tooth
  • When lucent space around crown is greater than __mm, it’s considered a dentigerous cyst
  • Most common site
  • Most common age
A

the crown and the REE (reduced enamel epithelium)

  • unerupted
  • 3-4mm
  • mand 3rd molar , followed by max canines
  • 2nd-3rd decades (3rd molars erupting)
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21
Q

Adentigerous cyst that forms in the soft tissue

A

Eruption cyst

22
Q

Eruption cyst color can be ___ because of ____

A

Blue b/c of bleeding

23
Q

Rare lesion thought to be derived from degenerating tooth bud epithelium

A

Primordial Cyst

24
Q

Which cyst develops in place of a tooth, before any mineralized material is deposited

A

Primordial Cyst

25
Q

Usually detected as a unilocular radiolucency in the area of a missing 3rd molar (NOT surgically removed…naturally missing)

A

Primordial Cyst

26
Q

Locally aggressive cyst associated with nevoid basal cell carcinoma syndrome:
-This specific association is suspected in pts under __yrs old

A

Odontogenic Keratocyst

-15

27
Q

Odontogenic Keratocyst peak age:

  • More common in mandible or maxilla?
  • At what age is anterior maxilla more favored?
  • Present as __locular radio___
  • Tx depends on:
  • Prognosis:
A

3rd decade

  • Mandible twice as common
  • Over 60
  • UNIlocular radioLUCENCY
  • Size
  • guarded (3-62% recurrence)
28
Q

Complex mix of malformations and neoplams exhibiting over 100 different features related to skin, CNS, and skeleton:

A

Nevoid Basal Cell Carcinoma Syndroma

29
Q

Nevoid Basal Cell Carcinoma Syndrome…

  • __ gene, chromosome __
  • 40% are __ mutations
  • Craniofacial features:
  • Affect on skin
  • Radiographic findings
  • Which cysts develop in jaws
A
  • PTCH gene, chromosome 9
  • new
  • Enlarged cranial circumference, heavy brow ridges
  • 1-2mm shallow pits on palms and soles
  • Lamellar calcification of falx cerebri
  • Odontogenic Keratocysts
30
Q

Presents as 1-2mm yellow-white papules on maxillary ridge of newborn

A

Gingival Cyst of newborn

31
Q

Similar appearing lesions to gingival cyst of newborn..

  • Epstein pearls:
  • Bohn’s Nodules
A
  • occur along median palatal raphe and arise from epithelium entrapped along the line of fusion
  • scattered over the hard palate, often near the soft palate junction; believed to be derived from the minor salivary glands
32
Q

Gingival Cyst of Adult…

  • Related to ______ cyst
  • Arises from:
  • Area
  • __ on Palpation
  • Predilection?
  • Tx
A
  • lateral periodontal cyst
  • dental lamina rests in the gingival connective tissue (rests of Serres)
  • Attached gingiva of Canine/premolar
  • tense
  • None
  • Conservative excision
33
Q

What mimics mucocele (blue) but on ATTACHED gingiva

A

Gingival Cyst of Adult

34
Q

Lateral Periodontal Cyst..

  • Are adjacent teeth vital?
  • Area
  • Tx:
A
  • yes
  • mandibular premolar, maxillary lateral incisor
  • Curettage
35
Q

Calcifying Odontogenic Cyst…

  • Aka _____ cyst
  • Maxilla/mandible predilection?
  • Mean age
  • Scattered radiopacities in __% of cases
  • __% of COC’s are associated with impacted tooth, __% with odontoma
  • Resorption of adjacent roots happens in __% of cases
A
  • Gorlin
  • Nope
  • 33 yrs old
  • 50%
  • impacted 30%, odontoma 20%
  • resorption 80%
36
Q

Most common odontogenic neoplasm

A

Ameloblastoma

37
Q

Ameloblastoma..

  • Sex predilection?
  • Age range
  • __% occur in mandible (posterior)
  • __% are associated with impacted tooth
  • Growth rate?
  • Does it perforate bone?
  • Symptoms?
A
  • No sex pred
  • Very wide 3rd-7th
  • 80%
  • 20%
  • Slow
  • no, it expands
  • none except swelling
38
Q

Radiograph shows poorly demarcated radiolucency with numerous radiopaque flecks

A

Desmoplastic Variant of Ameloblastoma

39
Q

Ameloblastoma…

  • Small lesion tx:
  • Large lesion tx:
  • prognosis:
  • Does maxilla or mandible require more aggressive surgical removal (due to anatomical location)
A
  • Small: aggressive curettage or small en bloc resection
  • Large: large n bloc resection or marginal segmental resection with reconstruction
  • Guarded (high recurrence)
  • Maxilla
40
Q

Peripheral Ameloblastoma presents as:

-Prognosis

A

asymptomatic gingival mass in middle-aged adult, usually mandible
-GOOD (this is an innocuous lesion that can easily be cured by local excision, low recurrence)

41
Q

Calcidying Epithelial Odontogenic Tumor (CEOT)..

  • aka
  • mean age
  • Sex predilection
  • area
  • __% associated w impacted tooth
  • Radiographically
  • tx
  • __% recurrence rate
A
  • Pindborg Tumor
  • 40
  • none
  • posterior mandible
  • 50%
  • well-circumscribed radiolucency. Can have radiopaque flecks
  • Conservative excision with peripheral ostectomy
  • 15%
42
Q

Adenomatoid Odontogenic Tumor (AOT)…

  • Mean age:
  • Sex predilection?
  • Maxilla/mandible predilection?
  • Tx:
  • Prog
A
  • 18yrs
  • female 2:1
  • maxilla 2:1
  • Enucleation
  • Excellent
43
Q

Adenomatoid Odontogenic Tumor (AOT)..

  • 75% occur in anterior/posterior
  • __% are associated with impacted tooth
  • Symptoms?
  • Radiographically
  • Affect on adjacent teeth?
A
  • Anterior
  • 75%
  • Asymptomatic
  • Well-circumscribed radiolucency w radiopaque flecks
  • Separation of roots/teeth
44
Q

How can you tell the difference of an Adenomatoid Odontogenic Tumor (AOT) from dentigerous cyst

A

When AOT is associated with impacted tooth, the lesion often extends apically beyond the CEJ

45
Q

Ameloblastic Fibroma…

  • Usually in younger/older
  • 70% of cases in what area
  • tx:
  • Prog
  • Malignant transformation common?
A
  • Younger
  • Posterior mandible
  • aggressive curettage
  • good
  • NO, NOT common
46
Q

Odontogenic tumor with features of ameloblastic fibroma as well as odontoma

A

Ameloblastic Fibro-Odontoma

47
Q

Ameloblastic Fibro-Odontoma..

  • mean age
  • Max/mand predilection
  • Radiographically it has varying amounts of calcified material having the density of:
  • often associated with:
  • tx:
  • prog
A
  • 10
  • nope
  • tooth structures
  • impacted tooth
  • Conservative curettage
  • excellent
48
Q

Odontoma…

  • What are the 2 different forms?
  • Mean age
  • Usually associated with:
A
  • compound or complex
  • 14
  • unerupted tooth
49
Q

Difference of compound and complex Odontomas?

-Where are each usually seen

A
  • Compound: collection of small malformed teeth often overlying an impacted tooth (ANTERIOR MAXILLA)
  • Complex: calcified mass that has same density of tooth structure also overlying impacted tooth (POSTERIOR MAXILLA OR MANDIBLE)
50
Q

Odontogenic Myxoma…

  • ONLY affects which part of body:
  • Average age:
  • Symptoms:
  • Radiographically may have “____” appearance
  • Tx depends on
  • Recurrence rate:
A
  • Jaw Bones
  • 25
  • Asymptomatic expansion of the bone
  • “soap-bubble”
  • size (small=curettage…large=en bloc or segmental resection)
  • 25%
51
Q

Cementoblastoma…

  • Area
  • Age
  • Sex predilection?
  • Rate of growth
  • Tx
  • Prog
A
  • Mandibular molar region
  • Under 25
  • none
  • slow (can produce expansion or pain)
  • Surgical extraction of involved tooth
  • Excellent
52
Q

What is a well-circumscribed radiOPAQUE mass with a fine radiolucent border. Fused to the resorbed root of the mandibular first molar

A

Cementoblastoma

Oral Path 2 (7 decks)

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