Exam 3 Endocrine Disorders Flashcards
Hypothyroidism =
Diagnosed via =
= low or no production of T4, involves the thyroid and anterior pituitary gland
= newborn screening (1/40,000)
S/S of Hypothyroidism
- Large Fontanels
- Protruding tongue
- Umbilical Hernia
- Lethargy, Fatigue
- Constipation
- Prolonged jaundice (in newborn period)
- dry skin, brittle hair/nails
Diagnosis/Prevention/Teaching for Hypothyroidism
- ____ diagnosis to prevent?
- N___ S____
- Screen ____/____ in childhood/teens
- Early, prevent cognitive deficits
- Newborn Screen
- T4 (low), TSH (high)
Tx for Hypothyroidism
- Daily ______*
- Serum ___ and ___ testing at each well visit
SYNTHROID*
- T4 (low), TSH (high)
Precocious Puberty =
Girls =
Boys =
= Early physical sexual development
= < 9 y
= < 9.5 y
Causes of Precocious Puberty (5)
Why is it important to check for precocious puberty?
1) Obesity
2) Heredity
3) Stress
4) Environmental exposure
5) Adrenal, CNS, Gonad tumors
Tumors are major factor
S/S of Precocious Puberty for Girls/Boys?
- Advanced ____ staging
Girls = breast development, pubic hair, axillary hair, growth spurt, early menarche Boys = voice changes, testicular enlargement, penile growth
Tx for Precocious Puberty = *
Teach parents how to?
Treat child how?*
Monthly IM injection of LUPRON*
- how to administer
- treat age appropriately**
Precocious Puberty, monitor what hormones (4)
FSH, LH, Testosterone, Estrogen
Type I Diabetes Mellitus =
Destruction of pancreatic beta cells ->
Almost always ___ mediated, __ known cause
= Autoimmune illness which is caused by insulin deficiency followed by destruction of insulin producing pancreatic beta cells
- > absolute insulin deficiency
- immune, no known cause (idiopathic)
Type II Diabetes Mellitus =
- Ability to -> _____ but inability to -> ____ causing ->
- Can result in beta cell _____ -> eventually leads to complete ____ _____
=combination of insulin resistance due to failure of insulin to act on tissues and relative insulin deficiency
- Ability to produce insulin but inability to use it correctly -> causing excessive production of insulin
- exhaustion -> insulin deficiency
Risk Factors for Type II DM
- Obesity BMI > ___%
- Family History of? Mother with?
- Physical ____
- Races (4)
- Greater in boys or girls?
- > 85%
- hx of Type II, Mother with gestational diabetes
- physical inactivity
- AA, American Indians, Hispanic, Asian Americans
- Girls
S/S of Type II DM
- ____ uria
- Recurrent _____
- Increase in ___, ____
- _____ ______** (early or late sign?)
- Ketonuria
- Recurrent infections
- Increase thirst, urination
- Acanthosis Nigricans (early sign) - velvety thickening and darkening of skin found on back of neck, axillae, medical aspect of thighs or any folds (80%)
Diagnosis of Type II DM
- Fasting Glucose >/- ____
- Random Glucose >/- _____, ____ symptoms
- Oral glucose tolerance test (OGTT) >/- _____
> /- 126
/- 200, with
/- 200
Tx of Type II DM * =
- D___ and E____
= Metformin* -> increases insulin sensitivity, suppresses appetite, improves lipid profile, and reduces hepatic glucose output
- Diet, Exercise