Exam 3 Cardiovascular and Lympatic Diseases Flashcards

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1
Q

Over ______% of plaque deposits in coronary arteries contain ______.

A

90%

Chlamydia pneumonia

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2
Q

What is the pericardium?

A

membrane layer around heart

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3
Q

What is pericarditis and myocarditis and each organismic cause?

A

Inflammation of pericardium
Inflammation of heart muscles
Staphylococcus aureus

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4
Q

What is the organismic cause of Anthrax?

A

Bacillus Anthracis

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5
Q

Describe 4 details of the bacillus antracis microbe.

A

Large
Gram POS
Faculative anaerobe- prefers oxygen but can live w/out
Endospores remain for 5o yrs.

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6
Q

Name the types of antrax diseases and their respective probability as well as fatality rate.

A

Cutaneous 90% (1% fatal)
Respiratory 5% (100% fatal)
Intestinal 5% (25%-50% deathly)

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7
Q

Describe 2 S&S of cutaneous Anthrax.

A

Develop 2-5 days after spore entry

Lesion center is black and necrotic leaving scars

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8
Q

Define necrotic.

A

dead cells/tissue

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9
Q

Describe S&S of intestinal Anthrax.

A

Similar to food poisoning

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10
Q

Describe 2 S&S of Respiratory Anthrax.

A

Clots formed in pulmonary capillaries & lymph nodes

Swelling obstructs airway

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11
Q

What is an AKA & cause for bubonic plague?

A

Pneumonic plague

Yersinia pestis

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12
Q

Describe 3 facts of the bubonic plague microbe?

A

Short
Gram NEG
Bacillus

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13
Q

What are common causes and method of spread of bubonic plague? (2)

A
Biological Vector(?)- spread by infected rodents with fleas carrying the organism
Poor sanitation
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14
Q

What system does the Yersinia pestis travel though and what are its 3 S&S?

A

Travels through lympatics
Buboes- lymph node inflammation in axilla or groin
Homorrhages- turns skin black
Septicemic plague- fatal

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15
Q

Describe 3 pneumonic plague facts.

A

It is the bubonic plague when involved with lungs
Martality rate- 100%
Spread- by droplet aerosols

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16
Q

Define zoonosis.

A

DZ that can be transmitted to humans from animals

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17
Q

What causes Tularemia and what is an aka for this disease?

A

Francisella tularensis

Rabbit fever

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18
Q

What disease are taxidermists susceptible to?

A

Tularemia

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19
Q

What are the 6 S&S of tularemia?

A
High Fever (104-106)
Severe headache
Chills
Shaking
Ulcer at site of entry 
Buboes
20
Q

What are the S&S, AKA’s, and cause of Brucellosis?

A

Brucella melitensis
Undulant fever
Malta fever
Fever cycle- high in afternoon/low at night after profuse sweating

21
Q

What causes relapsing fever?

A

Borrelia species

Gram negative spirochete

22
Q

How is relapsing fever transferred?

A

Tick

Louse

23
Q

What are the 4 steps of S&S of relapsing fever?

A

Develops after 3-5d incubation
Lasts 3-7d
None 7-10d
Returns 2-3d

24
Q

What other disease does the relapsing fever microbe cause?

A

Lymes Disease- Borrelia burgdorferi

25
Q

How is Lyme disease transmitted?

A

Tick

26
Q

What are the 4 S&S of Lyme disease?

A

Hallmark- bull’s eye rash at bite site
Arthritis
myocarditis
demyelination- causes dimentia

27
Q

What type of microbes are obligate (needs host to survive) intracellular parasites?

A

Ricketssial

28
Q

Name 5 Rickettsial diseases and their respective microbe.

A
Typhus fever
Epidemic typhus
Endemic (murine) typhus
Scrub typhus
Brill Zinsser disease
29
Q

What microbe causes epidemic typhus?

A

Rickettsia prowazekii

30
Q

What is a louse?

A

parasite that lives on skin

31
Q

Describe in detail 5 S&S of epidemic typhus.

A
Fever
Severe headache
6-7d of rash beginning on truck and spread to extremeties (rarely on sole or palm)
Liver and spleen enlargement
40% mortality rate
32
Q

Describe 3 facts of Brill Zinsser disease and its S&S.

A

Recurrence of typhus infection from latent organisms in Lymphs
Short duration
No Rash

33
Q

What causes endemic (murine) typhus?

A

Rickettsia tyhpi

34
Q

How is epidemic typhus transmitted?

A

body louse

35
Q

How is endemic typhus transmitted and what is its martality rate as well as state of higher incidence?

A

Fleas (not lice like in epidemic)
Low mortality
High in TX

36
Q

What causes Scrub typhus?

A

Rickettsia Tsutsugamushi

37
Q

How is scrub typhus transmitted?

A

Mite transmission

38
Q

What is an aka for rocky mountain spotted fever and what species is it apart of?

A

Rickettsia Rickettsii

Dermacentor spp

39
Q

What are the 4 S&S of rocky mountain spottted fever

A

Fever
Headache
Weakness
Rash- begins ankles and wrist, prominent on palms and soles, progress toward trunk

40
Q

What is the natural mortality rate of rocky mountain spotted fever and its mortality rate after antibiotic treatment?

A

80%

5%-10%

41
Q

What is shinbone fever an aka for?

A

Trench Fever

42
Q

What causes Trench fever?

A

Bartonella quintana

43
Q

Describe Trench fever’s microbe.

A

Gram NEG
Bacillus
intracellular parasite of RBC

44
Q

What are the S&S of Trench fever?

A

Vascular inflammation

Endocarditis

45
Q

What are the 3 hemorrhagic fevers, their respective virus, and country commonly seen in?

A

Ebola virus- Africa
Marbug virus- Germany
Lassa Fever- Africa