Exam 3

Question 1

Properdin

Answer 1

A protein that stabilized the C3 convertase generated in the alternative complement pathway

Question 2

Haptoglobin

Answer 2

An acute-phase reactant that binds irreversibly to free hemoglobin released by intravascular hemolysis

Question 3

Fibrinogen

Answer 3

An acute-phase reactant that changes to fibrin and forms clots in the bloodstream

Question 4

Ceruloplasm

Answer 4

An acute-phase reactant that acts as the principal copper-transporting protein in human plasma

Question 5

Acute-phase reactants

Answer 5

Normal serum proteins that increase rapidly as a result of infection, injury, or trauma to the tissues

Question 6

Chemotaxis

Answer 6

The migration of cells in the direction of a chemical messenger

Question 7

Alpha1-antitrypsin (AAT)

Answer 7

An acute-phase protein that acts as an inhibitor of proteases released from WBCs

Question 8

Alternative pathway

Answer 8

A means of activating complement proteins without an antigen-antibody combination. This pathway is triggered by constituents of microorganisms.

Question 9

Lectin pathway

Answer 9

A pathway for the activation of complement based on binding of mannose-binding protein to constituents on bacterial cell walls

Question 10

Classical pathway

Answer 10

A means of activating complement that begins with antigen-antibody combinations