Cells of the Immune System Flashcards
Learn the cells of the immune system
Where are neutrophils found?
50 - 75 % of ciculating WBCs, also in tissue
What are the functions of neutrophils?
First responder to infection, phagocytosis
Where are eosinophils found?
1 - 3 % of circulating white blood cells
What are the functions of eosinophils?
Kill parasites, neutralize basophil and mast cell products, regulate mast cells
Where are basophils found?
< 1 % of circulating white blood cells
What are the functions of basophils?
Induce and maintain allergic reactions, stimulate production of IgE
Where are mast cells located?
Found in skin, connective tissue, mucosal epithelium
What are the functions of mast cells?
Antigen presentation to T and B cells, enhancement and suppression of the adaptive immune response
Where are monocytes found?
4 - 10% of circulating WBCs
What are the functions of monocytes?
Phagocytosis; migrate to tissues to become macrophages
Where are macrophages found?
In lungs, liver, brain, bone, connective tissue, other tissue
What are the functions of macrophages?
Phagocytosis; kill intracellular parasites; tumoricidal activity; antigen presentation to T and B cells
Where are dendritic cells found?
In skin, mucous membranes, heart, lungs, liver, kidney, other tissue
What are the functions of dendritic cells?
Most potent phagocytic cell; most effective at antigen presentation
Where are lymphocytes found?
20 - 40% of circulating WBCs; also found in lymph nodes, spleen, other secondary lymphoid organs
