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Oral Pathology D2 > exam 3 > Flashcards

exam 3 Flashcards

1
Q

What is the most common inflam odontogenic cyst?

A

periapical cyst

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2
Q

compare periapical granuloma, cyst and abscess?

A
  • all from rests of malassez
  • all non-vital
  • only the abscess causes pain (with acute inflammatory cells)
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3
Q

What is a buccal bifurcation cyst?

What tooth is it common in?

A

This is a paradental cyst - this is an uncommon odontogenic cyst that develops on the buccal aspect of mandibular first molar
* 5-11 years, occlusal radiograph

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4
Q

lateral periodontal cyst

A

uncommon
80% MN canine-PM
gingival counterpart is gingival cyst
no inflam bc developmental

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5
Q

botryoid

A

multilocular

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6
Q

gingival cysts on adults

A

cause cupping of bone
facial aveolar mucosa
blue/grey… 60 yrs

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7
Q

bohn’s nodules

A

keratin cysts… gingival cyst of a new born
ON Alveolar MUCOSA
(Pearls on palate)

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8
Q

most common developmental odontogenic cyst ?

Details?

A

dentigerous cyst (follicular)

  • unilocular
  • root resorption
  • attaches AT CEJ
  • rarely but can undergo neoplastic transformation
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9
Q

eruption cysts common where?

A

MX 1 st molars and incisors

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10
Q

MULTIPLE OKC IS GOING TO BE ASSCOAITED WITH?

A

NEVOID BASLA CELL CARCINOMA or Gorlins Syndrome

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11
Q

MACHO

for multiocular radioloucency differencial diagnosis

A 
Myxoma
Ameloblastoma
Central Giant Cell Granuloma
Hemangioma
OKC
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12
Q

OKC

A 
cystic neoplasm
PTCH gene 9q22
developmental
recurs 30%, 60-80% in MN
satalite cysts and retes
10-40 yrs, bimodal... men
no root resorb
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13
Q

Gorlin syndrome
aka nevoid basal cell carcinoma

3 features?
overexoression of?

A

PTCH gene

  • overexpress: Cyclin D1 and p53
    1) intracranial calcification
  • -frontal bossing
    2) multiple jaw cysts (OKCs)
    • bifid ribs 75%
      3) palmar pitting 60%
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14
Q

why must you excise skin lesions in nevoid basal cell carcinoma?

A

aggressive basal cell carcinoma with metastasis have been reported

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15
Q

orthokeratinized odontogenic cyst (OOC)

A

NOT associated with basal cell carcinoma
not a clinical cyst but refers to a odontogenic cyst with orthokeratinization in lining
- 30% with impacted tooth
-80% resorption

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16
Q

COC (calcifying odontogenic cysts) associated with?

A

-maybe associated with hamartoma, ameloblastomas, AOT

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17
Q

ghost cells

A

CCOT or COC

And odontomas

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18
Q

what are the only two keratinized cysts?

A

keratinized: OOC and OKC

FU: COC and OKC

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19
Q

glandular odontogenic cyst

A

sialo-odontogenic cysts that shows aggressive behavior that has glandular or salivary features (aka mucous cells) indicating pluripotential nature of the odontogenic epithelium

GOD ONLY KNOWS

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20
Q

Do carcinomas arise from odontogenic cysts? What is the percent?

A

only 1-2% of oral carcinomas come from odontogenic cysts… 25% of which seem to arise from the dentigerous cyst s

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21
Q

What are the four non-odontogenic cyst to know?

What is the most common non-odntogenic cyst

A

Globulomaxillary cyst

Nasolabial cyst

Median MN mandibular

Nasoplanatine duct or canal cyst MOST COMMON

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22
Q

globularmaxillary cyst clinical or diagnosis term?

A

clinical

23
Q

nasolabial cyst

A

developmental soft tissue cyst located in 1) the cupsid-lateral incisor area or 2) on the upper lip to the midline

May arise due to remnants along the lines of fusion of maxillary, medial, nasal and lateral processes due to epithelial remenants of the naso-lacrimal duct

*asymptomatic unless 2nd infection
* elevate nose/lip
GOBLET CELLS

24
Q

nasopalatine cyst

A

1% most common non-odntogenic cyst (MUST BE GREATER than 6mm heart shapedbw centrals)

  • boney cyst, will have NERVES and VESSELS
  • Entrapped epithelial cells from the nasopalatine duct
  • males 40-60yrs
  • SWELLING anterior hard palate, salty taste
  • asymptomatic but may hurt while eating
25
Q

What is a pseudocyst - definition?

FAST (what are the 4 types)

A

A cyst with No epithelial lining

FAST

1) Focal osteoporotic bone defect (W, ill defined radiograph)
2) Aneurysmal bone cyst (Young)
3) Stafne bone cyst (M)
4) Traumatic bone cyst (scalloping bw roots)

26
Q

traumatic bone cyst

A

result from intraosseous hematoma
-no epithelial lining, and uninflammed fibrous connective tissue, RBC, giant cells
-10-20 asymptomatic painless swelling
MN

27
Q

aneurysmal bone cyst (ABC)

caused by?

A

caused by: Traumatic event, Vascular malformation, Neoplasm

  • in long bones, 2% of time in MN
  • swelling and pain
  • could be A in MACHO
28
Q

Stafne’s defect?

A

90% MEN
asymptomatic radiolucency below the mandibular canal but above the lower border of the mandible in the posterior mandible by 1st molar
*Salivary gland lobules that come from the submandibular gland

29
Q

What is an FOMD?

A

Focal Osteoporotic Marrow Defect
WOMEN in posterios
*unique bc ill defined

30
Q

What are the 3 soft tissue “true” cysts?

A

Dermoid cysts

Branchial cyst/lymphoepithelial

Thyroglossal tract cyst
**all true cyts

31
Q

Dermoid cysts

A

developmental TERATOMA cyst (all 3 germ layers)
*above mylohyoid= painless, doughy FOM
below= submental swelling

32
Q

branchail cyst aka lymphoepithelial cyst

A

occurs in lymphoid tissue such as Waldeyers ring including palantine tonsils, lingual tonsils, and pharyngeal adenoids

  • FOM
  • true cyst, small, well circumscribed swellings that are yellow when superifical or pink when deeper
33
Q

ameloblastoma

A

soap bubble and honeycomb
M=W, more in AA
-worry when it is solid
desmoblastic ameloblastoma occurs in ANERTERIOR MAXILLA whereas it typically in Post MN
**B/L expansion (remember OKC had antirior/posterior)

34
Q

lingual thyroid

A

uncommon nodule of the thyroid tissue that is found posterior to the foramen cecum in the posterior 1/3 of the tongue
WOMEN
70% etopic htyroid tissue

35
Q

branchial cleft cyst

A

cyst formed from the degenerative tissue of the second branchial arch

  • lateral aspect of anterior SCM
  • needs surgical removal, 50-90% recur
  • MX harder to heal
36
Q

demsoplastic ameloblastoma

A

in anterior MX when most ameloblastomas are in Post MN

  • also diff. from ameloblastoma bc diffuse and ill defined
  • **Mcune Albright syndrome
37
Q

ameloblastoma histology

A

1) Follicular - most common, likes like enamel organ
2) plexiform -cube/columnar
3) acanthomatous -keratin pearls present, SCC
4) granular cell pattern -young, agressive, turn into granular cells
5) desmoplastic -TGF-B, islands and cords
6) basal cell -LEAST common pattern

38
Q

unicystic ameloblastoma

A

ameloblastoma that is NOT as solid tumor like multi is

This is the called cystic bc its lesions are unilocular with cortical perforations

Dentigerous cyst either becoming ameloblastoma OR originates as a de novo neoplasm
*YOUNG (20s)

39
Q

If you see a large, radiolucent lesion, what should you do?

A

aspiration

40
Q

What are the three types of histopaths for unicystics?

A

1) Luminal type which is where the tumor is confined to the luminal surface with a lining that’s like a traditional ameloblastoma
2) Intraluminal or plexiform that is going to have nodules small or large - so like the islands or cords
3) Mural which is going to be a fibrous wall of a cyst has follicles

41
Q

peripheral ameloblastoma

A

arise from rests of dental lamina and basal cells of epi

  • basically a gingival bump
  • post MN ging or alveolar mucosa
42
Q

malignant vs ameloblastic carcinoma

A

Malignant ameloblastoma = younger, well differentiated

Ameloblast carcinoma = less differentiated - look likes dysplastic cells and epithelial cells, hard to control

43
Q

order of ameloblastoma recurance?

A

solid (50-90%) > peripheral (15%) > unicystic(10%)

44
Q

calcifying epithelial odontogenic tumor (CEOT)

A 
2-10 decade with average of 34
2x more common in MN
M=W
peripheral and central
uni or multi
D/D radiolucent=dentigerous and mixed=COC
45
Q

pindborg tumor aka?

A

calcifying epithelial odontogenic tumor (CEOT)

46
Q

Adenomatoid Odontogenic Tumor (AOT)

A

odontogenic tumor that is arranged in the form of glands and ducts

  • HAMARTOMA; mixed neoplasm
  • F>M, teenagers
  • gingival fibrous lesoin may be present
  • SNOWFLAKES due to foci calcification
47
Q

squamous odontogenic tumor (SOT)

A

benign odontogenic neoplasm-rare

  • arrise from dental lamina and malassez
  • M=W,MN=MX (MX more aggressive)
  • located in bone lateral to root surface of erupted bone
48
Q

odontogenic myxoma

A

benign, aggressive and reoccurring tumor

  • MN and 25yrs (no sex)
  • agrressive bc of massive cortical expansion
  • radiolucent honeycomb
  • stellate spindle cells

recur 25%

49
Q

Central odontogenic fibroma

A

Occurs in the jaw bone that is the counter part to the peripheral odontogenic fibroma

  • ant MX or post MN
  • looks like McFlurry
50
Q

recurrance rate of ameloblastic firoma?

A

43.5%

51
Q

complex vs compound odontoma

A

Complex odontomas = amorphous conglomerations of hard tissue with no idea which itssue is which post MN

Compound odontoma = numerous miniature rudimentary teeth (all 3 layers of tooth) ant MX

*HAMARTOMAS

52
Q

Liesegang rings and eosinophils

A

CEOT

53
Q

Dentigerous cyst

A 
3-4mm
PROPLASIA
attaches at CEJ
Most common devel odontogenous cyst
Blood becomes cholesterol
Marsupilization
54
Q

OKC regrows easy Bc?

A

1) flat, no Reten, attachment allowing lining to be left

2) daughter/satalite cells

Oral Pathology D2 (8 decks)

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