Exam 3 Flashcards
How many days does it take for hematopoesis?
5 days
What is the lifespan of an RBC After maturity?
120 days
Fe deficiency anemia equals what size cells?
Small
Folic acid deficient anemia equals what size cells?
Large cells. Can lead to Neuro tube defect.
Neutrophils
First to arrive. Short lived phagocytosis.
Monocytes
Long term phagocytosis. Macrophages in spleen eat up RBC’s.
Lymphocytes
T cells. B cells( plasma cells to make antibodies/immunoglobulins).
Eosinophils
Allergic reaction. Neutralizes histamine. Kill parasites.
Basophils
Make and store histamine.
Where are platelets formed?
Bone marrow.
They nurture and maintain lining of vessels.
What are the symptoms of ITP?
Petechia, bruises, gums, blood in void/stool, menstrual.
What are some causes of thrombocytopenia?
ETOH, CA, sepsis,decreased B12 and folic acid absorption, aplastic anemia, drugs.
Can be a decrease in production, increase in destruction, or an increased consumption(trapped).
What happens in ITP?
Is it the most common?
Platelets are coated with antibodies and the spleen recongnizes them as foreign.(macrophages)
Yes
TTP
Less common
No anticlotting enzymes which enhances agglutination.
What do you give to someone who has HITT
Protamine sulfate
Can you get a hemostasis disorder from HTN?
Yes the HTN causes turbulent blood flow
Over activation of clotting factors with enhanced fibrin.
DIC. Give heparin to reset the cascade.
What are some S/S of DIC
Epistaxis, broken vessel in eye, restless, shocky, joint bleeds(swelling), do UA. D-dimer will be increased.
What is pernicious anemia?
The intrinsic factor is worn out. Can’t process B12.